Sphera Funds Management

Latest statistics and disclosures from Sphera Funds Management's latest quarterly 13F-HR filing:

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Positions held by Sphera Funds Management consolidated in one spreadsheet with up to 7 years of data

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Portfolio Holdings for Sphera Funds Management

Sphera Funds Management holds 98 positions in its portfolio as reported in the December 2025 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Teva Pharmaceutical Inds Sponsored Ads (TEVA) 6.8 $35M -25% 1.1M 31.21
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Biogen Idec (BIIB) 3.2 $17M +14% 95k 175.99
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Mineralys Therapeutics (MLYS) 3.1 $16M +104% 449k 36.29
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Syndax Pharmaceuticals (SNDX) 3.1 $16M +96% 763k 21.01
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NOVA MEASURING Instruments L (NVMI) 3.0 $16M +8% 48k 328.39
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Ultragenyx Pharmaceutical (RARE) 2.9 $15M +84% 651k 23.00
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Tower Semiconductor Shs New (TSEM) 2.8 $14M -60% 123k 117.42
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Cogent Biosciences (COGT) 2.6 $13M +284% 379k 35.52
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Astrazeneca Sponsored Adr 2.4 $12M 135k 91.93
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Praxis Precision Medicines I Com New Call Option (PRAX) 2.3 $12M -62% 40k 294.74
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Sanofi Sa Sponsored Adr (SNY) 2.2 $12M +9% 240k 48.46
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Eli Lilly & Co. (LLY) 1.9 $9.7M -9% 9.0k 1074.68
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Amicus Therapeutics (FOLD) 1.8 $9.4M -33% 658k 14.24
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Immatics SHS (IMTX) 1.7 $9.0M +47% 861k 10.50
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BioMarin Pharmaceutical (BMRN) 1.7 $8.7M NEW 147k 59.43
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Spdr Series Trust State Street Spd Put Option (XBI) 1.6 $8.5M NEW 70k 121.93
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Bridgebio Pharma (BBIO) 1.6 $8.2M -36% 108k 76.49
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Oric Pharmaceuticals (ORIC) 1.6 $8.2M +132% 1.0M 8.18
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Dyne Therapeutics (DYN) 1.5 $7.7M -7% 393k 19.56
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Trevi Therapeutics (TRVI) 1.4 $7.5M -22% 599k 12.52
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Johnson & Johnson (JNJ) 1.4 $7.4M -12% 36k 206.95
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Savara (SVRA) 1.4 $7.1M -12% 1.2M 6.03
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Scholar Rock Hldg Corp (SRRK) 1.3 $7.0M NEW 158k 44.05
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Wave Life Sciences SHS (WVE) 1.3 $6.9M +716% 408k 17.00
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Cybin Com New (HELP) 1.3 $6.8M +122% 826k 8.18
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Annexon (ANNX) 1.3 $6.6M -26% 1.3M 5.02
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BioCryst Pharmaceuticals (BCRX) 1.3 $6.5M NEW 838k 7.80
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Celldex Therapeutics Com New (CLDX) 1.3 $6.5M +15% 240k 27.16
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Soleno Therapeutics (SLNO) 1.2 $6.3M +227% 136k 46.30
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Apellis Pharmaceuticals (APLS) 1.2 $6.3M +294% 251k 25.12
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Nice Sponsored Adr Call Option (NICE) 1.2 $6.3M -64% 56k 113.04
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GSK Sponsored Adr (GSK) 1.2 $6.0M 122k 49.04
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4068594 Enphase Energy (ENPH) 1.2 $6.0M +598% 187k 32.05
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Novo-nordisk A S Adr (NVO) 1.1 $5.9M +9% 116k 50.88
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Cytokinetics Com New (CYTK) 1.1 $5.8M -43% 92k 63.54
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Abbvie (ABBV) 1.1 $5.8M 25k 228.49
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Solaredge Technologies (SEDG) 1.1 $5.7M +39% 197k 28.85
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ACADIA Pharmaceuticals (ACAD) 1.1 $5.7M +42% 212k 26.71
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Vor Biopharma Com New (VOR) 1.0 $5.4M NEW 410k 13.08
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Merck & Co (MRK) 1.0 $5.1M 49k 105.26
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Novartis Sponsored Adr (NVS) 1.0 $5.1M 37k 137.87
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Forte Biosciences Com New (FBRX) 1.0 $5.1M -60% 186k 27.27
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Kodiak Sciences (KOD) 0.9 $4.9M NEW 176k 27.96
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Tango Therapeutics (TNGX) 0.9 $4.8M NEW 545k 8.86
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Solaredge Technologies Note 2.250% 7/0 0.9 $4.7M 4.0M 1.17
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Astria Therapeutics 0.9 $4.7M +41% 356k 13.09
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Mediwound Shs New (MDWD) 0.8 $4.3M +24% 230k 18.46
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Camtek Ord (CAMT) 0.8 $4.2M +35% 40k 106.34
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Revolution Medicines (RVMD) 0.8 $4.2M -12% 53k 79.65
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Ishares Tr 20 Yr Tr Bd Etf Call Option (TLT) 0.8 $4.1M 47k 87.16
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Advanced Micro Devices (AMD) 0.7 $3.9M +16% 18k 214.16
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Eliem Therapeutics (CLYM) 0.7 $3.7M +114% 932k 4.00
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Alpha Cognition Com New (ACOG) 0.7 $3.7M +67% 568k 6.50
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Enliven Therapeutics (ELVN) 0.7 $3.5M +35% 227k 15.40
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Protara Therapeutics Com Stk (TARA) 0.7 $3.5M NEW 650k 5.33
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Broadcom (AVGO) 0.7 $3.4M +48% 9.8k 346.10
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Eledon Pharmaceuticals (ELDN) 0.6 $3.2M +44% 2.1M 1.51
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Bioage Labs (BIOA) 0.6 $3.2M NEW 243k 13.23
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Corvus Pharmaceuticals (CRVS) 0.6 $3.1M 408k 7.70
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Elbit Sys Ord (ESLT) 0.6 $3.1M -20% 5.3k 577.71
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Kura Oncology (KURA) 0.6 $3.1M +20% 296k 10.39
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Maze Therapeatics (MAZE) 0.6 $3.0M -53% 72k 41.43
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Zim Integrated Shipping Serv SHS (ZIM) 0.6 $2.9M NEW 136k 21.23
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Structure Therapeutics Sponsored Ads (GPCR) 0.6 $2.9M -81% 41k 69.55
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Evommune Com Shs (EVMN) 0.5 $2.8M NEW 166k 17.12
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Verastem Com New (VSTM) 0.5 $2.7M +338% 344k 7.72
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Amgen (AMGN) 0.5 $2.5M -21% 7.5k 327.31
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Nurix Therapeutics (NRIX) 0.5 $2.4M NEW 124k 18.97
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Ascendis Pharma A/s Sponsored Adr (ASND) 0.5 $2.3M NEW 11k 213.24
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Tenax Therapeutics Com New (TENX) 0.4 $2.3M NEW 190k 12.19
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Janux Therapeutics (JANX) 0.4 $2.2M +83% 158k 13.80
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Pfizer (PFE) 0.4 $2.1M 86k 24.90
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Taysha Gene Therapies Com Shs (TSHA) 0.4 $2.0M -9% 368k 5.50
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Contineum Therapeutics Cl A (CTNM) 0.4 $2.0M NEW 174k 11.43
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Madrigal Pharmaceuticals (MDGL) 0.4 $1.9M NEW 3.3k 582.34
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Pharvaris N V (PHVS) 0.3 $1.8M -46% 64k 27.75
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Varonis Sys (VRNS) 0.3 $1.7M -28% 53k 32.80
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Precision Biosciences Com New (DTIL) 0.3 $1.6M NEW 396k 4.16
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Ventyx Biosciences (VTYX) 0.3 $1.6M -59% 180k 9.03
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Ishares Bitcoin Trust Etf Shs Ben Int (IBIT) 0.3 $1.5M +40% 30k 49.65
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Day One Biopharmaceuticals I (DAWN) 0.3 $1.4M -17% 145k 9.32
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Voyager Therapeutics (VYGR) 0.3 $1.3M +70% 340k 3.93
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Entrada Therapeutics (TRDA) 0.2 $1.1M NEW 111k 10.28
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Tenaya Therapeutics (TNYA) 0.2 $1.1M NEW 1.5M 0.71
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Perspective Therapeutics Com New (CATX) 0.2 $962k -31% 350k 2.75
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Bristol Myers Squibb (BMY) 0.2 $944k 18k 53.94
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Jasper Therapeutics Com New (JSPR) 0.2 $888k -22% 485k 1.83
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Pepgen (PEPG) 0.2 $791k -29% 122k 6.51
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Shattuck Labs (STTK) 0.1 $713k NEW 195k 3.65
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Palisade Bio (PALI) 0.1 $433k NEW 184k 2.35
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Werewolf Therapeutics (HOWL) 0.1 $397k 627k 0.63
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Skye Bioscience Com New (SKYE) 0.1 $359k 479k 0.75
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Prelude Therapeutics (PRLD) 0.1 $356k NEW 123k 2.90
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Aprea Therapeutics Com New (APRE) 0.0 $230k 270k 0.85
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Onkure Therapeutics Com Cl A (OKUR) 0.0 $175k 61k 2.90
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Mereo Biopharma Group Spon Ads (MREO) 0.0 $106k NEW 255k 0.42
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Promis Neurosciences Com Shs (PMN) 0.0 $81k NEW 12k 6.83
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Applied Therapeutics 0.0 $5.0k 50k 0.10
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Past Filings by Sphera Funds Management

SEC 13F filings are viewable for Sphera Funds Management going back to 2013

View all past filings