Sphera Funds Management as of Dec. 31, 2025
Portfolio Holdings for Sphera Funds Management
Sphera Funds Management holds 98 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Teva Pharmaceutical Inds Sponsored Ads (TEVA) | 6.8 | $35M | 1.1M | 31.21 | |
| Biogen Idec (BIIB) | 3.2 | $17M | 95k | 175.99 | |
| Mineralys Therapeutics (MLYS) | 3.1 | $16M | 449k | 36.29 | |
| Syndax Pharmaceuticals (SNDX) | 3.1 | $16M | 763k | 21.01 | |
| NOVA MEASURING Instruments L (NVMI) | 3.0 | $16M | 48k | 328.39 | |
| Ultragenyx Pharmaceutical (RARE) | 2.9 | $15M | 651k | 23.00 | |
| Tower Semiconductor Shs New (TSEM) | 2.8 | $14M | 123k | 117.42 | |
| Cogent Biosciences (COGT) | 2.6 | $13M | 379k | 35.52 | |
| Astrazeneca Sponsored Adr | 2.4 | $12M | 135k | 91.93 | |
| Praxis Precision Medicines I Com New Call Option (PRAX) | 2.3 | $12M | 40k | 294.74 | |
| Sanofi Sa Sponsored Adr (SNY) | 2.2 | $12M | 240k | 48.46 | |
| Eli Lilly & Co. (LLY) | 1.9 | $9.7M | 9.0k | 1074.68 | |
| Amicus Therapeutics (FOLD) | 1.8 | $9.4M | 658k | 14.24 | |
| Immatics SHS (IMTX) | 1.7 | $9.0M | 861k | 10.50 | |
| BioMarin Pharmaceutical (BMRN) | 1.7 | $8.7M | 147k | 59.43 | |
| Spdr Series Trust State Street Spd Put Option (XBI) | 1.6 | $8.5M | 70k | 121.93 | |
| Bridgebio Pharma (BBIO) | 1.6 | $8.2M | 108k | 76.49 | |
| Oric Pharmaceuticals (ORIC) | 1.6 | $8.2M | 1.0M | 8.18 | |
| Dyne Therapeutics (DYN) | 1.5 | $7.7M | 393k | 19.56 | |
| Trevi Therapeutics (TRVI) | 1.4 | $7.5M | 599k | 12.52 | |
| Johnson & Johnson (JNJ) | 1.4 | $7.4M | 36k | 206.95 | |
| Savara (SVRA) | 1.4 | $7.1M | 1.2M | 6.03 | |
| Scholar Rock Hldg Corp (SRRK) | 1.3 | $7.0M | 158k | 44.05 | |
| Wave Life Sciences SHS (WVE) | 1.3 | $6.9M | 408k | 17.00 | |
| Cybin Com New (HELP) | 1.3 | $6.8M | 826k | 8.18 | |
| Annexon (ANNX) | 1.3 | $6.6M | 1.3M | 5.02 | |
| BioCryst Pharmaceuticals (BCRX) | 1.3 | $6.5M | 838k | 7.80 | |
| Celldex Therapeutics Com New (CLDX) | 1.3 | $6.5M | 240k | 27.16 | |
| Soleno Therapeutics (SLNO) | 1.2 | $6.3M | 136k | 46.30 | |
| Apellis Pharmaceuticals (APLS) | 1.2 | $6.3M | 251k | 25.12 | |
| Nice Sponsored Adr Call Option (NICE) | 1.2 | $6.3M | 56k | 113.04 | |
| GSK Sponsored Adr (GSK) | 1.2 | $6.0M | 122k | 49.04 | |
| 4068594 Enphase Energy (ENPH) | 1.2 | $6.0M | 187k | 32.05 | |
| Novo-nordisk A S Adr (NVO) | 1.1 | $5.9M | 116k | 50.88 | |
| Cytokinetics Com New (CYTK) | 1.1 | $5.8M | 92k | 63.54 | |
| Abbvie (ABBV) | 1.1 | $5.8M | 25k | 228.49 | |
| Solaredge Technologies (SEDG) | 1.1 | $5.7M | 197k | 28.85 | |
| ACADIA Pharmaceuticals (ACAD) | 1.1 | $5.7M | 212k | 26.71 | |
| Vor Biopharma Com New (VOR) | 1.0 | $5.4M | 410k | 13.08 | |
| Merck & Co (MRK) | 1.0 | $5.1M | 49k | 105.26 | |
| Novartis Sponsored Adr (NVS) | 1.0 | $5.1M | 37k | 137.87 | |
| Forte Biosciences Com New (FBRX) | 1.0 | $5.1M | 186k | 27.27 | |
| Kodiak Sciences (KOD) | 0.9 | $4.9M | 176k | 27.96 | |
| Tango Therapeutics (TNGX) | 0.9 | $4.8M | 545k | 8.86 | |
| Solaredge Technologies Note 2.250% 7/0 | 0.9 | $4.7M | 4.0M | 1.17 | |
| Astria Therapeutics | 0.9 | $4.7M | 356k | 13.09 | |
| Mediwound Shs New (MDWD) | 0.8 | $4.3M | 230k | 18.46 | |
| Camtek Ord (CAMT) | 0.8 | $4.2M | 40k | 106.34 | |
| Revolution Medicines (RVMD) | 0.8 | $4.2M | 53k | 79.65 | |
| Ishares Tr 20 Yr Tr Bd Etf Call Option (TLT) | 0.8 | $4.1M | 47k | 87.16 | |
| Advanced Micro Devices (AMD) | 0.7 | $3.9M | 18k | 214.16 | |
| Eliem Therapeutics (CLYM) | 0.7 | $3.7M | 932k | 4.00 | |
| Alpha Cognition Com New (ACOG) | 0.7 | $3.7M | 568k | 6.50 | |
| Enliven Therapeutics (ELVN) | 0.7 | $3.5M | 227k | 15.40 | |
| Protara Therapeutics Com Stk (TARA) | 0.7 | $3.5M | 650k | 5.33 | |
| Broadcom (AVGO) | 0.7 | $3.4M | 9.8k | 346.10 | |
| Eledon Pharmaceuticals (ELDN) | 0.6 | $3.2M | 2.1M | 1.51 | |
| Bioage Labs (BIOA) | 0.6 | $3.2M | 243k | 13.23 | |
| Corvus Pharmaceuticals (CRVS) | 0.6 | $3.1M | 408k | 7.70 | |
| Elbit Sys Ord (ESLT) | 0.6 | $3.1M | 5.3k | 577.71 | |
| Kura Oncology (KURA) | 0.6 | $3.1M | 296k | 10.39 | |
| Maze Therapeatics (MAZE) | 0.6 | $3.0M | 72k | 41.43 | |
| Zim Integrated Shipping Serv SHS (ZIM) | 0.6 | $2.9M | 136k | 21.23 | |
| Structure Therapeutics Sponsored Ads (GPCR) | 0.6 | $2.9M | 41k | 69.55 | |
| Evommune Com Shs (EVMN) | 0.5 | $2.8M | 166k | 17.12 | |
| Verastem Com New (VSTM) | 0.5 | $2.7M | 344k | 7.72 | |
| Amgen (AMGN) | 0.5 | $2.5M | 7.5k | 327.31 | |
| Nurix Therapeutics (NRIX) | 0.5 | $2.4M | 124k | 18.97 | |
| Ascendis Pharma A/s Sponsored Adr (ASND) | 0.5 | $2.3M | 11k | 213.24 | |
| Tenax Therapeutics Com New (TENX) | 0.4 | $2.3M | 190k | 12.19 | |
| Janux Therapeutics (JANX) | 0.4 | $2.2M | 158k | 13.80 | |
| Pfizer (PFE) | 0.4 | $2.1M | 86k | 24.90 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.4 | $2.0M | 368k | 5.50 | |
| Contineum Therapeutics Cl A (CTNM) | 0.4 | $2.0M | 174k | 11.43 | |
| Madrigal Pharmaceuticals (MDGL) | 0.4 | $1.9M | 3.3k | 582.34 | |
| Pharvaris N V (PHVS) | 0.3 | $1.8M | 64k | 27.75 | |
| Varonis Sys (VRNS) | 0.3 | $1.7M | 53k | 32.80 | |
| Precision Biosciences Com New (DTIL) | 0.3 | $1.6M | 396k | 4.16 | |
| Ventyx Biosciences (VTYX) | 0.3 | $1.6M | 180k | 9.03 | |
| Ishares Bitcoin Trust Etf Shs Ben Int (IBIT) | 0.3 | $1.5M | 30k | 49.65 | |
| Day One Biopharmaceuticals I (DAWN) | 0.3 | $1.4M | 145k | 9.32 | |
| Voyager Therapeutics (VYGR) | 0.3 | $1.3M | 340k | 3.93 | |
| Entrada Therapeutics (TRDA) | 0.2 | $1.1M | 111k | 10.28 | |
| Tenaya Therapeutics (TNYA) | 0.2 | $1.1M | 1.5M | 0.71 | |
| Perspective Therapeutics Com New (CATX) | 0.2 | $962k | 350k | 2.75 | |
| Bristol Myers Squibb (BMY) | 0.2 | $944k | 18k | 53.94 | |
| Jasper Therapeutics Com New (JSPR) | 0.2 | $888k | 485k | 1.83 | |
| Pepgen (PEPG) | 0.2 | $791k | 122k | 6.51 | |
| Shattuck Labs (STTK) | 0.1 | $713k | 195k | 3.65 | |
| Palisade Bio (PALI) | 0.1 | $433k | 184k | 2.35 | |
| Werewolf Therapeutics (HOWL) | 0.1 | $397k | 627k | 0.63 | |
| Skye Bioscience Com New (SKYE) | 0.1 | $359k | 479k | 0.75 | |
| Prelude Therapeutics (PRLD) | 0.1 | $356k | 123k | 2.90 | |
| Aprea Therapeutics Com New (APRE) | 0.0 | $230k | 270k | 0.85 | |
| Onkure Therapeutics Com Cl A (OKUR) | 0.0 | $175k | 61k | 2.90 | |
| Mereo Biopharma Group Spon Ads (MREO) | 0.0 | $106k | 255k | 0.42 | |
| Promis Neurosciences Com Shs (PMN) | 0.0 | $81k | 12k | 6.83 | |
| Applied Therapeutics | 0.0 | $5.0k | 50k | 0.10 |
