Sr One Capital Management
Latest statistics and disclosures from Sr One Capital Management's latest quarterly 13F-HR filing:
- Top 5 stock holdings are ACLX, CRSP, ZBIO, MLYS, ORIC, and represent 82.17% of Sr One Capital Management's stock portfolio.
- Added to shares of these 1 stock: CRSP (+$64M).
- Reduced shares in these 2 stocks: MLYS (-$39M), KALA.
- Sold out of its position in KALA.
- Sr One Capital Management was a net buyer of stock by $23M.
- Sr One Capital Management has $691M in assets under management (AUM), dropping by 49.86%.
- Central Index Key (CIK): 0001910264
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Portfolio Holdings for Sr One Capital Management
Sr One Capital Management holds 12 positions in its portfolio as reported in the September 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Arcellx Common Stock (ACLX) | 27.9 | $193M | 2.3M | 82.10 |
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| CRISPR Therapeutics Common Shares (CRSP) | 19.1 | $132M | +94% | 2.0M | 64.81 |
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| Zenas BioPharma Common Stock (ZBIO) | 15.8 | $109M | 4.9M | 22.20 |
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| Mineralys Therapeutics Common Stock (MLYS) | 11.6 | $80M | -32% | 2.1M | 37.92 |
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| ORIC Pharmaceuticals Common Stock (ORIC) | 7.8 | $54M | 4.5M | 12.00 |
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| Design Therapeutics Common Stock (DSGN) | 7.1 | $49M | 6.5M | 7.53 |
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| ARS Pharmaceuticals Common Stock (SPRY) | 5.8 | $40M | 4.0M | 10.05 |
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| Oruka Therapeutics Common Stock (ORKA) | 1.2 | $8.3M | 430k | 19.23 |
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| Alumis Common Stock (ALMS) | 1.1 | $7.8M | 2.0M | 3.99 |
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| Nkarta Common Stock (NKTX) | 1.0 | $6.9M | 3.3M | 2.07 |
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| Oculis Holding Ordinary Shares (OCS) | 0.8 | $5.7M | 323k | 17.58 |
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| enGene Holdings Common Shares (ENGN) | 0.7 | $5.1M | 748k | 6.83 |
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Past Filings by Sr One Capital Management
SEC 13F filings are viewable for Sr One Capital Management going back to 2021
- Sr One Capital Management 2025 Q3 filed Nov. 12, 2025
- Sr One Capital Management 2025 Q2 filed Aug. 14, 2025
- Sr One Capital Management 2025 Q1 filed May 13, 2025
- Sr One Capital Management 2024 Q4 filed Feb. 13, 2025
- Sr One Capital Management 2024 Q3 filed Nov. 13, 2024
- Sr One Capital Management 2024 Q2 filed Aug. 13, 2024
- Sr One Capital Management 2024 Q1 filed May 13, 2024
- Sr One Capital Management 2023 Q4 filed Feb. 12, 2024
- Sr One Capital Management 2023 Q3 filed Nov. 13, 2023
- Sr One Capital Management 2023 Q2 filed Aug. 10, 2023
- Sr One Capital Management 2023 Q1 restated filed May 19, 2023
- Sr One Capital Management 2023 Q1 filed May 9, 2023
- Sr One Capital Management 2022 Q4 filed Feb. 8, 2023
- Sr One Capital Management 2022 Q3 filed Nov. 8, 2022
- Sr One Capital Management 2022 Q2 filed Aug. 2, 2022
- Sr One Capital Management 2022 Q1 filed May 10, 2022