Sr One Capital Management
Latest statistics and disclosures from Sr One Capital Management's latest quarterly 13F-HR filing:
- Top 5 stock holdings are ZBIO, ACLX, CRSP, DSGN, MLYS, and represent 79.39% of Sr One Capital Management's stock portfolio.
- Added to shares of these 3 stocks: OCS (+$6.4M), ZBIO, RARE.
- Started 1 new stock position in RARE.
- Reduced shares in these 1 stock: MLYS (-$20M).
- Sr One Capital Management was a net seller of stock by $-5.8M.
- Sr One Capital Management has $706M in assets under management (AUM), dropping by 2.16%.
- Central Index Key (CIK): 0001910264
Tip: Access up to 7 years of quarterly data
Positions held by Sr One Capital Management consolidated in one spreadsheet with up to 7 years of data
Download as csv
Download as Excel
Portfolio Holdings for Sr One Capital Management
Sr One Capital Management holds 13 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Zenas BioPharma Common Stock (ZBIO) | 25.9 | $183M | +2% | 5.0M | 36.31 |
|
| Arcellx Common Stock (ACLX) | 21.7 | $153M | 2.3M | 65.20 |
|
|
| CRISPR Therapeutics Common Shares (CRSP) | 15.1 | $107M | 2.0M | 52.44 |
|
|
| Design Therapeutics Common Stock (DSGN) | 8.7 | $61M | 6.5M | 9.38 |
|
|
| Mineralys Therapeutics Common Stock (MLYS) | 8.0 | $57M | -26% | 1.6M | 36.29 |
|
| ARS Pharmaceuticals Common Stock (SPRY) | 6.6 | $47M | 4.0M | 11.65 |
|
|
| ORIC Pharmaceuticals Common Stock (ORIC) | 5.3 | $38M | 4.5M | 8.36 |
|
|
| Alumis Common Stock (ALMS) | 2.7 | $19M | 2.0M | 9.76 |
|
|
| Oruka Therapeutics Common Stock (ORKA) | 1.8 | $13M | 430k | 30.31 |
|
|
| Oculis Holding Ordinary Shares (OCS) | 1.8 | $13M | +98% | 641k | 19.97 |
|
| enGene Holdings Common Shares (ENGN) | 1.0 | $6.8M | 748k | 9.03 |
|
|
| Nkarta Common Stock (NKTX) | 0.9 | $6.2M | 3.3M | 1.85 |
|
|
| Ultragenyx Pharmaceutical Common Stock (RARE) | 0.4 | $3.2M | NEW | 138k | 23.00 |
|
Past Filings by Sr One Capital Management
SEC 13F filings are viewable for Sr One Capital Management going back to 2021
- Sr One Capital Management 2025 Q4 filed Feb. 12, 2026
- Sr One Capital Management 2025 Q3 filed Nov. 12, 2025
- Sr One Capital Management 2025 Q2 filed Aug. 14, 2025
- Sr One Capital Management 2025 Q1 filed May 13, 2025
- Sr One Capital Management 2024 Q4 filed Feb. 13, 2025
- Sr One Capital Management 2024 Q3 filed Nov. 13, 2024
- Sr One Capital Management 2024 Q2 filed Aug. 13, 2024
- Sr One Capital Management 2024 Q1 filed May 13, 2024
- Sr One Capital Management 2023 Q4 filed Feb. 12, 2024
- Sr One Capital Management 2023 Q3 filed Nov. 13, 2023
- Sr One Capital Management 2023 Q2 filed Aug. 10, 2023
- Sr One Capital Management 2023 Q1 restated filed May 19, 2023
- Sr One Capital Management 2023 Q1 filed May 9, 2023
- Sr One Capital Management 2022 Q4 filed Feb. 8, 2023
- Sr One Capital Management 2022 Q3 filed Nov. 8, 2022
- Sr One Capital Management 2022 Q2 filed Aug. 2, 2022