Sr One Capital Management as of Dec. 31, 2025
Portfolio Holdings for Sr One Capital Management
Sr One Capital Management holds 13 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Zenas BioPharma Common Stock (ZBIO) | 25.9 | $183M | 5.0M | 36.31 | |
| Arcellx Common Stock (ACLX) | 21.7 | $153M | 2.3M | 65.20 | |
| CRISPR Therapeutics Common Shares (CRSP) | 15.1 | $107M | 2.0M | 52.44 | |
| Design Therapeutics Common Stock (DSGN) | 8.7 | $61M | 6.5M | 9.38 | |
| Mineralys Therapeutics Common Stock (MLYS) | 8.0 | $57M | 1.6M | 36.29 | |
| ARS Pharmaceuticals Common Stock (SPRY) | 6.6 | $47M | 4.0M | 11.65 | |
| ORIC Pharmaceuticals Common Stock (ORIC) | 5.3 | $38M | 4.5M | 8.36 | |
| Alumis Common Stock (ALMS) | 2.7 | $19M | 2.0M | 9.76 | |
| Oruka Therapeutics Common Stock (ORKA) | 1.8 | $13M | 430k | 30.31 | |
| Oculis Holding Ordinary Shares (OCS) | 1.8 | $13M | 641k | 19.97 | |
| enGene Holdings Common Shares (ENGN) | 1.0 | $6.8M | 748k | 9.03 | |
| Nkarta Common Stock (NKTX) | 0.9 | $6.2M | 3.3M | 1.85 | |
| Ultragenyx Pharmaceutical Common Stock (RARE) | 0.4 | $3.2M | 138k | 23.00 |
