Baker Bros. Advisors as of Dec. 31, 2014
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 121 positions in its portfolio as reported in the December 2014 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Pharmacyclics | 11.4 | $1.1B | 9.1M | 122.26 | |
| Incyte Corporation (INCY) | 11.1 | $1.1B | 15M | 73.11 | |
| Synageva Biopharma | 10.1 | $989M | 11M | 92.79 | |
| Seattle Genetics | 9.1 | $895M | 28M | 32.13 | |
| AVANIR Pharmaceuticals | 6.7 | $653M | 39M | 16.95 | |
| ACADIA Pharmaceuticals (ACAD) | 6.6 | $650M | 21M | 31.75 | |
| Salix Pharmaceuticals Inc note 2.750% 5/1 | 5.5 | $542M | 219M | 2.47 | |
| Genomic Health | 4.5 | $437M | 14M | 31.97 | |
| Incyte Corp Ltd conv | 4.3 | $423M | 275M | 1.54 | |
| Incyte Corp Incy Cvt 144a 0.37 convert | 4.0 | $389M | 259M | 1.50 | |
| BioMarin Pharmaceutical (BMRN) | 3.4 | $336M | 3.7M | 90.40 | |
| Incyte Corp note 4.750%10/0 | 3.4 | $336M | 40M | 8.31 | |
| Anacor Pharmaceuticals In | 1.4 | $136M | 4.2M | 32.25 | |
| BioCryst Pharmaceuticals (BCRX) | 1.3 | $130M | 11M | 12.16 | |
| Biomarin Pharmaceutical Inc note 1.875% 4/2 | 1.0 | $102M | 23M | 4.46 | |
| Bellicum Pharma | 1.0 | $99M | 4.3M | 23.04 | |
| Gilead Sciences conv | 0.9 | $89M | 22M | 4.14 | |
| Dyax | 0.9 | $87M | 6.2M | 14.06 | |
| Salix Pharmaceuticals | 0.8 | $73M | 635k | 114.94 | |
| Cerus Corporation (CERS) | 0.8 | $73M | 12M | 6.24 | |
| Acorda Therap note 1.75% 6/15 | 0.7 | $70M | 61M | 1.15 | |
| Medivation Inc note 2.625% 4/0 | 0.7 | $67M | 35M | 1.94 | |
| Vanda Pharmaceuticals (VNDA) | 0.7 | $64M | 4.5M | 14.32 | |
| XenoPort | 0.6 | $61M | 6.9M | 8.77 | |
| XOMA CORP Common equity shares | 0.6 | $61M | 17M | 3.59 | |
| Versartis | 0.5 | $51M | 2.3M | 22.45 | |
| Mirati Therapeutics | 0.5 | $44M | 2.4M | 18.52 | |
| Dbv Technologies S A (DBVT) | 0.4 | $41M | 1.5M | 27.12 | |
| Progenics Pharmaceuticals | 0.3 | $34M | 4.4M | 7.56 | |
| Derma Sciences | 0.3 | $33M | 3.5M | 9.31 | |
| Tg Therapeutics (TGTX) | 0.3 | $33M | 2.1M | 15.84 | |
| Acorda Therapeutics | 0.3 | $31M | 756k | 40.87 | |
| Slxp 1 1/2 03/15/19 | 0.3 | $27M | 15M | 1.82 | |
| Halozyme Therapeutics (HALO) | 0.3 | $27M | 2.8M | 9.65 | |
| Heron Therapeutics (HRTX) | 0.3 | $26M | 2.6M | 10.06 | |
| Gilead Sciences (GILD) | 0.2 | $24M | 256k | 94.26 | |
| Repros Therapeutics | 0.2 | $20M | 2.0M | 9.97 | |
| Catalyst Pharmaceutical Partners (CPRX) | 0.2 | $20M | 6.7M | 2.97 | |
| Agios Pharmaceuticals (AGIO) | 0.2 | $18M | 163k | 112.04 | |
| Insmed (INSM) | 0.2 | $17M | 1.1M | 15.47 | |
| Omeros Corporation (OMER) | 0.2 | $16M | 648k | 24.78 | |
| Sangamo Biosciences (SGMO) | 0.1 | $15M | 955k | 15.21 | |
| Biomarin Pharmaceutical Inc note 0.750%10/1 | 0.1 | $15M | 13M | 1.18 | |
| Bluebird Bio (BLUE) | 0.1 | $14M | 150k | 91.72 | |
| Neurocrine Biosciences (NBIX) | 0.1 | $12M | 555k | 22.34 | |
| Clovis Oncology | 0.1 | $11M | 203k | 56.00 | |
| Macrogenics (MGNX) | 0.1 | $11M | 312k | 35.07 | |
| Kythera Biopharmaceuticals I | 0.1 | $9.9M | 286k | 34.68 | |
| Xencor (XNCR) | 0.1 | $9.5M | 591k | 16.04 | |
| Arrowhead Research | 0.1 | $9.1M | 1.2M | 7.38 | |
| Aerie Pharmaceuticals | 0.1 | $8.7M | 299k | 29.19 | |
| Aquinox Pharmaceuticals | 0.1 | $9.1M | 1.2M | 7.50 | |
| Proqr Thrapeutics N V shs euro (PRQR) | 0.1 | $8.7M | 400k | 21.67 | |
| Osiris Therapeutics | 0.1 | $8.2M | 511k | 15.99 | |
| Sunesis Pharmaceuticals | 0.1 | $8.2M | 3.2M | 2.55 | |
| La Jolla Pharmaceuticl Com Par | 0.1 | $7.8M | 422k | 18.45 | |
| Array BioPharma | 0.1 | $6.8M | 1.4M | 4.73 | |
| Novavax | 0.1 | $7.3M | 1.2M | 5.93 | |
| Idera Pharmaceuticals | 0.1 | $7.2M | 1.6M | 4.41 | |
| Threshold Pharmaceuticals | 0.1 | $6.9M | 2.2M | 3.18 | |
| Tekmira Pharmaceuticals Corporation | 0.1 | $7.3M | 484k | 15.15 | |
| Chimerix (CMRX) | 0.1 | $6.9M | 172k | 40.26 | |
| Ultragenyx Pharmaceutical (RARE) | 0.1 | $6.6M | 150k | 43.88 | |
| Celladon | 0.1 | $7.3M | 375k | 19.53 | |
| Concert Pharmaceuticals I equity | 0.1 | $6.7M | 505k | 13.32 | |
| Foamix Pharmaceuticals | 0.1 | $7.2M | 1.0M | 7.01 | |
| ISIS Pharmaceuticals | 0.1 | $5.9M | 96k | 61.74 | |
| Qlt | 0.1 | $6.2M | 1.5M | 4.01 | |
| D Stemline Therapeutics | 0.1 | $5.8M | 339k | 17.06 | |
| Infinity Pharmaceuticals (INFIQ) | 0.1 | $5.3M | 312k | 16.89 | |
| Ironwood Pharmaceuticals (IRWD) | 0.1 | $5.3M | 346k | 15.32 | |
| Achillion Pharmaceuticals | 0.1 | $5.4M | 438k | 12.25 | |
| Mallinckrodt Pub | 0.1 | $4.6M | 47k | 99.02 | |
| Alder Biopharmaceuticals | 0.1 | $4.5M | 153k | 29.09 | |
| Juno Therapeutics | 0.1 | $5.2M | 100k | 52.22 | |
| Amicus Therapeutics (FOLD) | 0.0 | $4.0M | 482k | 8.32 | |
| Ligand Pharmaceuticals In (LGND) | 0.0 | $3.9M | 73k | 53.22 | |
| Discovery Laboratories | 0.0 | $4.2M | 3.7M | 1.16 | |
| Cytrx | 0.0 | $3.7M | 1.4M | 2.74 | |
| Enanta Pharmaceuticals (ENTA) | 0.0 | $3.8M | 75k | 50.85 | |
| Epizyme | 0.0 | $3.8M | 202k | 18.87 | |
| Karyopharm Therapeutics (KPTI) | 0.0 | $3.5M | 94k | 37.43 | |
| Ignyta | 0.0 | $3.9M | 571k | 6.85 | |
| Neuroderm Ltd F | 0.0 | $3.5M | 250k | 14.04 | |
| BioDelivery Sciences International | 0.0 | $2.5M | 210k | 12.02 | |
| Zogenix | 0.0 | $3.2M | 2.4M | 1.37 | |
| Synergy Pharmaceuticals | 0.0 | $3.0M | 973k | 3.05 | |
| Biota Pharmaceuticals | 0.0 | $2.5M | 1.1M | 2.24 | |
| Mast Therapeutics | 0.0 | $2.7M | 4.8M | 0.56 | |
| Receptos | 0.0 | $2.9M | 24k | 122.51 | |
| Foundation Medicine | 0.0 | $2.8M | 126k | 22.22 | |
| Celsus Therapeutics Plc sponsored adr ne | 0.0 | $3.2M | 674k | 4.80 | |
| Lipocine | 0.0 | $2.6M | 500k | 5.26 | |
| Sage Therapeutics (SAGE) | 0.0 | $2.7M | 75k | 36.60 | |
| Aurinia Pharmaceuticals (AUPH) | 0.0 | $2.6M | 728k | 3.57 | |
| Affimed Therapeutics B V | 0.0 | $2.5M | 400k | 6.20 | |
| Protalix Biotherapeutics Inc note 4.500% 9/1 | 0.0 | $2.7M | 3.5M | 0.76 | |
| Aptose Biosciences | 0.0 | $2.8M | 479k | 5.91 | |
| OraSure Technologies (OSUR) | 0.0 | $2.4M | 235k | 10.14 | |
| Palatin Technologies | 0.0 | $1.5M | 2.1M | 0.73 | |
| Ophthotech | 0.0 | $1.7M | 37k | 44.87 | |
| Mediwound Ltd cmn | 0.0 | $1.5M | 225k | 6.66 | |
| Marinus Pharmaceuticals | 0.0 | $2.2M | 205k | 10.57 | |
| Proteon Therapeutics | 0.0 | $1.8M | 173k | 10.40 | |
| Dermira | 0.0 | $1.8M | 100k | 18.11 | |
| Synta Pharmaceuticals | 0.0 | $1.3M | 500k | 2.65 | |
| Geron Corporation (GERN) | 0.0 | $1.3M | 403k | 3.25 | |
| Rigel Pharmaceuticals (RIGL) | 0.0 | $1.1M | 482k | 2.27 | |
| Alnylam Pharmaceuticals (ALNY) | 0.0 | $1.1M | 12k | 96.98 | |
| ZIOPHARM Oncology | 0.0 | $982k | 194k | 5.07 | |
| Tesaro | 0.0 | $1.2M | 31k | 37.19 | |
| Alcobra | 0.0 | $1.1M | 290k | 3.73 | |
| Acceleron Pharma | 0.0 | $1.1M | 29k | 38.97 | |
| Five Prime Therapeutics | 0.0 | $535k | 20k | 26.99 | |
| Achaogen | 0.0 | $1.3M | 100k | 13.05 | |
| Loxo Oncology | 0.0 | $1.2M | 100k | 11.75 | |
| Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) | 0.0 | $82k | 13k | 6.19 | |
| Chemocentryx | 0.0 | $342k | 50k | 6.84 | |
| Uniqure Nv (QURE) | 0.0 | $454k | 31k | 14.80 | |
| Asterias Biotherapeutics | 0.0 | $54k | 17k | 3.22 | |
| Biotime Inc wts oct 1 18 | 0.0 | $22k | 21k | 1.07 |
