Baker Bros. Advisors as of Dec. 31, 2018
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 93 positions in its portfolio as reported in the December 2018 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seattle Genetics | 23.7 | $2.9B | 51M | 56.66 | |
| Incyte Corporation (INCY) | 17.8 | $2.2B | 34M | 63.59 | |
| Beigene (BGNE) | 13.7 | $1.7B | 12M | 140.26 | |
| Alexion Pharmaceuticals | 6.8 | $833M | 8.6M | 97.36 | |
| Genomic Health | 6.2 | $756M | 12M | 64.41 | |
| BioMarin Pharmaceutical (BMRN) | 5.3 | $646M | 7.6M | 85.15 | |
| ACADIA Pharmaceuticals (ACAD) | 5.3 | $642M | 40M | 16.17 | |
| Amarin Corporation (AMRN) | 4.8 | $580M | 43M | 13.61 | |
| Ascendis Pharma A S (ASND) | 1.5 | $178M | 2.8M | 62.65 | |
| Madrigal Pharmaceuticals (MDGL) | 1.1 | $132M | 1.2M | 112.72 | |
| Heron Therapeutics (HRTX) | 1.1 | $130M | 5.0M | 25.94 | |
| BioCryst Pharmaceuticals (BCRX) | 1.0 | $122M | 15M | 8.07 | |
| Mirati Therapeutics | 0.9 | $107M | 2.5M | 42.42 | |
| Argenx Se (ARGX) | 0.8 | $98M | 1.0M | 96.07 | |
| Kiniksa Pharmaceuticals | 0.7 | $84M | 3.0M | 28.09 | |
| Rhythm Pharmaceuticals (RYTM) | 0.6 | $73M | 2.7M | 26.88 | |
| Array BioPharma | 0.6 | $72M | 5.0M | 14.25 | |
| Kodiak Sciences (KOD) | 0.5 | $65M | 9.1M | 7.10 | |
| Neurocrine Biosciences Inc Note 2.250 5/1 | 0.5 | $63M | 53M | 1.19 | |
| Cerus Corporation (CERS) | 0.5 | $55M | 11M | 5.07 | |
| Spark Therapeutics | 0.4 | $54M | 1.4M | 39.14 | |
| Neurocrine Biosciences (NBIX) | 0.4 | $52M | 730k | 71.41 | |
| Principia Biopharma | 0.4 | $49M | 1.8M | 27.39 | |
| Clementia | 0.4 | $44M | 3.7M | 11.76 | |
| Invitae (NVTAQ) | 0.3 | $43M | 3.9M | 11.06 | |
| Gw Pharmaceuticals Plc ads | 0.3 | $42M | 428k | 97.39 | |
| Cymabay Therapeutics | 0.3 | $39M | 4.9M | 7.87 | |
| Tricida | 0.3 | $38M | 1.6M | 23.58 | |
| Dbv Technologies S A | 0.3 | $35M | 5.5M | 6.42 | |
| Zymeworks | 0.2 | $25M | 1.7M | 14.68 | |
| Insmed (INSM) | 0.2 | $24M | 1.9M | 13.12 | |
| Aquinox Pharmaceuticals | 0.2 | $24M | 11M | 2.16 | |
| Audentes Therapeutics | 0.2 | $19M | 911k | 21.32 | |
| Uniqure Nv (QURE) | 0.1 | $17M | 605k | 28.82 | |
| Xencor (XNCR) | 0.1 | $16M | 440k | 36.16 | |
| Aimmune Therapeutics | 0.1 | $16M | 674k | 23.92 | |
| Myokardia | 0.1 | $15M | 315k | 48.86 | |
| Merus N V (MRUS) | 0.1 | $16M | 1.2M | 14.00 | |
| Krystal Biotech (KRYS) | 0.1 | $16M | 785k | 20.78 | |
| Solid Biosciences | 0.1 | $16M | 588k | 26.80 | |
| Abeona Therapeutics | 0.1 | $15M | 2.1M | 7.14 | |
| Ra Pharmaceuticals | 0.1 | $15M | 823k | 18.20 | |
| Biomarin Pharma Inc convertible/ | 0.1 | $15M | 15M | 0.99 | |
| Aeglea Biotherapeutics | 0.1 | $13M | 1.7M | 7.49 | |
| Idera Pharmaceuticals | 0.1 | $13M | 4.8M | 2.77 | |
| Sangamo Biosciences (SGMO) | 0.1 | $12M | 1000k | 11.48 | |
| Contrafect | 0.1 | $11M | 7.2M | 1.53 | |
| Novavax | 0.1 | $8.7M | 4.7M | 1.84 | |
| Marker Therapeutics Ord | 0.1 | $8.3M | 1.5M | 5.55 | |
| Bellicum Pharma | 0.1 | $7.8M | 2.7M | 2.92 | |
| Anaptysbio Inc Common (ANAB) | 0.1 | $7.2M | 113k | 63.79 | |
| Catalyst Pharmaceutical Partners (CPRX) | 0.1 | $5.6M | 2.9M | 1.92 | |
| Spring Bk Pharmaceuticals In | 0.1 | $6.4M | 613k | 10.39 | |
| Albireo Pharma | 0.1 | $6.1M | 250k | 24.53 | |
| Inflarx Nv (IFRX) | 0.1 | $6.5M | 179k | 36.37 | |
| Halozyme Therapeutics (HALO) | 0.0 | $4.4M | 300k | 14.63 | |
| Autolus Therapeutics Plc spon ads (AUTL) | 0.0 | $5.1M | 157k | 32.84 | |
| Bluebird Bio (BLUE) | 0.0 | $4.0M | 40k | 99.20 | |
| Acceleron Pharma | 0.0 | $3.7M | 84k | 43.55 | |
| Assembly Biosciences | 0.0 | $3.4M | 149k | 22.62 | |
| Viking Therapeutics (VKTX) | 0.0 | $3.3M | 425k | 7.65 | |
| Syros Pharmaceuticals | 0.0 | $3.2M | 575k | 5.57 | |
| Forty Seven | 0.0 | $3.9M | 250k | 15.72 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.0 | $3.9M | 131k | 29.99 | |
| Alkermes (ALKS) | 0.0 | $2.0M | 67k | 29.51 | |
| Chemocentryx | 0.0 | $2.3M | 207k | 10.91 | |
| Galapagos Nv- (GLPG) | 0.0 | $2.3M | 25k | 91.74 | |
| Aevi Genomic | 0.0 | $2.8M | 4.0M | 0.70 | |
| Sierra Oncology | 0.0 | $2.6M | 2.0M | 1.32 | |
| G1 Therapeutics | 0.0 | $2.4M | 127k | 19.15 | |
| Apellis Pharmaceuticals (APLS) | 0.0 | $2.6M | 196k | 13.19 | |
| Menlo Therapeutics | 0.0 | $2.9M | 700k | 4.12 | |
| Y Mabs Therapeutics (YMAB) | 0.0 | $2.1M | 103k | 20.34 | |
| Orchard Therapeutics Plc ads | 0.0 | $2.0M | 125k | 15.73 | |
| Infinity Pharmaceuticals (INFIQ) | 0.0 | $685k | 580k | 1.18 | |
| Achillion Pharmaceuticals | 0.0 | $1.7M | 1.1M | 1.59 | |
| La Jolla Pharmaceuticl Com Par | 0.0 | $1.5M | 155k | 9.43 | |
| Galmed Pharmaceuticals | 0.0 | $1.5M | 216k | 6.83 | |
| Adamas Pharmaceuticals | 0.0 | $1.5M | 173k | 8.54 | |
| Foamix Pharmaceuticals | 0.0 | $1.8M | 498k | 3.59 | |
| Affimed Therapeutics B V | 0.0 | $622k | 200k | 3.11 | |
| Dynavax Technologies (DVAX) | 0.0 | $686k | 75k | 9.15 | |
| Proteon Therapeutics | 0.0 | $678k | 299k | 2.27 | |
| Trillium Therapeutics, Inc. Cmn | 0.0 | $864k | 505k | 1.71 | |
| Intellia Therapeutics (NTLA) | 0.0 | $1.8M | 129k | 13.65 | |
| Molecular Templates | 0.0 | $1.0M | 254k | 4.04 | |
| Arcus Biosciences Incorporated (RCUS) | 0.0 | $1.3M | 122k | 10.77 | |
| Aquestive Therapeutics (AQST) | 0.0 | $628k | 100k | 6.30 | |
| Aravive | 0.0 | $1.4M | 404k | 3.52 | |
| Sunesis Pharmaceuticals Inc Ne | 0.0 | $228k | 557k | 0.41 | |
| Fulgent Genetics (FLGT) | 0.0 | $396k | 125k | 3.17 | |
| Ritter Pharmaceuticals | 0.0 | $168k | 280k | 0.60 | |
| Constellation Pharmceticls I | 0.0 | $535k | 133k | 4.01 |
