Baker Bros. Advisors

Baker Bros. Advisors as of March 31, 2019

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 96 positions in its portfolio as reported in the March 2019 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seattle Genetics 23.9 $3.7B 51M 73.24
Incyte Corporation (INCY) 18.9 $2.9B 34M 86.01
Beigene (BGNE) 10.1 $1.6B 12M 132.00
Alexion Pharmaceuticals 7.4 $1.2B 8.6M 135.18
ACADIA Pharmaceuticals (ACAD) 6.8 $1.1B 40M 26.85
Amarin Corporation (AMRN) 5.7 $897M 43M 20.76
Genomic Health 4.6 $714M 10M 70.05
BioMarin Pharmaceutical (BMRN) 4.3 $674M 7.6M 88.83
Ascendis Pharma A S (ASND) 2.5 $399M 3.4M 117.70
Mirati Therapeutics (MRTX) 1.2 $184M 2.5M 73.30
Madrigal Pharmaceuticals (MDGL) 0.9 $147M 1.2M 125.26
Argenx Se (ARGX) 0.8 $127M 1.0M 124.84
BioCryst Pharmaceuticals (BCRX) 0.8 $123M 15M 8.14
Heron Therapeutics (HRTX) 0.8 $123M 5.0M 24.44
Neurocrine Biosciences (NBIX) 0.6 $97M 1.1M 88.10
Clementia 0.6 $97M 3.7M 26.10
Array BioPharma 0.6 $94M 3.8M 24.38
Invitae (NVTA) 0.6 $91M 3.9M 23.42
Spark Therapeutics 0.6 $86M 752k 113.88
Cymabay Therapeutics (CBAY) 0.5 $76M 5.7M 13.28
Rhythm Pharmaceuticals (RYTM) 0.5 $74M 2.7M 27.41
Gw Pharmaceuticals Plc ads 0.5 $72M 428k 168.57
Neurocrine Biosciences Inc Note 2.250 5/1 0.5 $72M 53M 1.35
Tricida 0.5 $70M 1.8M 38.62
Cerus Corporation (CERS) 0.4 $67M 11M 6.23
Audentes Therapeutics 0.4 $67M 1.7M 39.02
Insmed (INSM) 0.4 $60M 2.1M 29.07
Principia Biopharma 0.4 $61M 1.8M 34.00
Kodiak Sciences (KOD) 0.4 $60M 9.1M 6.53
Kiniksa Pharmaceuticals (KNSA) 0.3 $54M 3.0M 18.06
Myokardia 0.3 $53M 1.0M 51.99
Dbv Technologies S A (DBVT) 0.3 $43M 5.5M 7.71
Uniqure Nv (QURE) 0.2 $36M 605k 59.65
Aquinox Pharmaceuticals 0.2 $30M 11M 2.70
Zymeworks 0.2 $28M 1.7M 16.18
Krystal Biotech (KRYS) 0.2 $26M 785k 32.90
Ra Pharmaceuticals 0.1 $18M 823k 22.40
Axsome Therapeutics (AXSM) 0.1 $17M 1.2M 14.23
Merus N V (MRUS) 0.1 $17M 1.2M 14.77
Aimmune Therapeutics 0.1 $15M 674k 22.35
Biomarin Pharma Inc convertible/ 0.1 $16M 15M 1.03
Catalyst Pharmaceutical Partners (CPRX) 0.1 $15M 2.9M 5.10
Xencor (XNCR) 0.1 $13M 428k 31.06
Aeglea Biotherapeutics 0.1 $14M 1.7M 8.05
Dermira 0.1 $12M 907k 13.55
Idera Pharmaceuticals 0.1 $12M 4.8M 2.55
Sangamo Biosciences (SGMO) 0.1 $9.5M 1000k 9.54
Bellicum Pharma 0.1 $9.0M 2.7M 3.37
Abeona Therapeutics 0.1 $9.5M 1.3M 7.36
Marker Therapeutics Ord 0.1 $9.9M 1.5M 6.60
Albireo Pharma 0.1 $8.1M 250k 32.21
Anaptysbio Inc Common (ANAB) 0.1 $8.3M 113k 73.05
Bluebird Bio (BLUE) 0.0 $6.3M 40k 157.32
Spring Bk Pharmaceuticals In 0.0 $6.4M 613k 10.49
Apellis Pharmaceuticals (APLS) 0.0 $6.1M 314k 19.50
Inflarx Nv (IFRX) 0.0 $6.8M 179k 37.79
Menlo Therapeutics 0.0 $5.5M 700k 7.85
Halozyme Therapeutics (HALO) 0.0 $4.8M 300k 16.10
Acceleron Pharma 0.0 $3.9M 84k 46.57
Macrogenics (MGNX) 0.0 $5.4M 303k 17.98
Viking Therapeutics (VKTX) 0.0 $4.2M 425k 9.94
Syros Pharmaceuticals 0.0 $5.3M 575k 9.14
Protagonist Therapeutics (PTGX) 0.0 $5.1M 404k 12.57
Autolus Therapeutics Plc spon ads (AUTL) 0.0 $4.9M 157k 31.47
Forty Seven 0.0 $4.0M 250k 16.16
Acorda Therapeutics 0.0 $3.9M 292k 13.29
Achillion Pharmaceuticals 0.0 $3.2M 1.1M 2.96
Alkermes (ALKS) 0.0 $2.4M 67k 36.49
Chemocentryx 0.0 $2.9M 207k 13.89
La Jolla Pharmaceuticl Com Par 0.0 $3.2M 505k 6.43
Assembly Biosciences (ASMB) 0.0 $2.9M 149k 19.69
Galapagos Nv- (GLPG) 0.0 $3.0M 25k 117.78
Sierra Oncology 0.0 $3.4M 2.0M 1.71
Crinetics Pharmaceuticals In (CRNX) 0.0 $3.0M 131k 22.76
Y Mabs Therapeutics (YMAB) 0.0 $2.7M 103k 26.21
Aravive (ARAV) 0.0 $3.0M 431k 7.04
Infinity Pharmaceuticals (INFIQ) 0.0 $1.1M 580k 1.88
Galmed Pharmaceuticals 0.0 $1.8M 216k 8.17
Adamas Pharmaceuticals 0.0 $1.2M 173k 7.11
Foamix Pharmaceuticals 0.0 $1.9M 498k 3.75
Affimed Therapeutics B V (AFMD) 0.0 $840k 200k 4.20
Contrafect 0.0 $1.2M 2.9M 0.40
Cytomx Therapeutics (CTMX) 0.0 $2.1M 194k 10.75
Intellia Therapeutics (NTLA) 0.0 $2.2M 129k 17.08
G1 Therapeutics (GTHX) 0.0 $2.1M 127k 16.60
Molecular Templates 0.0 $1.5M 254k 5.81
Arcus Biosciences Incorporated (RCUS) 0.0 $1.5M 122k 12.49
Constellation Pharmceticls I 0.0 $1.8M 133k 13.55
Orchard Therapeutics Plc ads 0.0 $2.2M 125k 17.88
Harpoon Therapeutics 0.0 $2.0M 214k 9.47
Dynavax Technologies (DVAX) 0.0 $548k 75k 7.31
Trillium Therapeutics, Inc. Cmn 0.0 $334k 505k 0.66
Sunesis Pharmaceuticals Inc Ne 0.0 $674k 557k 1.21
Fulgent Genetics (FLGT) 0.0 $744k 125k 5.95
Ritter Pharmaceuticals 0.0 $244k 280k 0.87
Aquestive Therapeutics (AQST) 0.0 $688k 100k 6.91