Baker Bros. Advisors as of March 31, 2021
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 126 positions in its portfolio as reported in the March 2021 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seagen | 28.5 | $6.6B | 47M | 138.86 | |
| BeiGene Sponsored Adr (BGNE) | 17.6 | $4.1B | 12M | 348.08 | |
| Incyte Corporation (INCY) | 11.3 | $2.6B | 32M | 81.27 | |
| Kodiak Sciences (KOD) | 6.8 | $1.6B | 14M | 113.39 | |
| ACADIA Pharmaceuticals (ACAD) | 4.7 | $1.1B | 42M | 25.80 | |
| Alexion Pharmaceuticals | 2.6 | $611M | 4.0M | 152.91 | |
| Invitae (NVTAQ) | 2.6 | $602M | 16M | 38.21 | |
| BioMarin Pharmaceutical (BMRN) | 2.5 | $573M | 7.6M | 75.51 | |
| Ascendis Pharma A/S Sponsored Adr (ASND) | 2.0 | $456M | 3.5M | 128.88 | |
| Prelude Therapeutics (PRLD) | 1.9 | $439M | 10M | 43.33 | |
| Abcellera Biologics (ABCL) | 1.5 | $355M | 11M | 33.96 | |
| argenx SE Sponsored Adr (ARGX) | 1.3 | $308M | 1.1M | 275.39 | |
| Igm Biosciences (IGMS) | 1.0 | $242M | 3.2M | 76.69 | |
| Mirati Therapeutics | 1.0 | $242M | 1.4M | 171.30 | |
| Madrigal Pharmaceuticals (MDGL) | 0.8 | $175M | 1.5M | 116.97 | |
| Amarin Corporation Sponsored Adr (AMRN) | 0.7 | $164M | 27M | 6.21 | |
| Global Blood Therapeutics In | 0.6 | $131M | 3.2M | 40.75 | |
| BioCryst Pharmaceuticals (BCRX) | 0.6 | $129M | 13M | 10.17 | |
| Immunocore Holdings Ads (IMCR) | 0.5 | $107M | 2.5M | 42.57 | |
| Pacific Biosciences of California (PACB) | 0.5 | $107M | 3.2M | 33.31 | |
| Instil Bio | 0.4 | $98M | 3.9M | 25.08 | |
| Talis Biomedical Corp | 0.4 | $97M | 7.6M | 12.85 | |
| Heron Therapeutics (HRTX) | 0.4 | $97M | 6.0M | 16.21 | |
| Cerus Corporation (CERS) | 0.4 | $82M | 14M | 6.01 | |
| Allakos (ALLK) | 0.3 | $81M | 703k | 114.78 | |
| DBV Technologies Sponsored Adr | 0.3 | $78M | 15M | 5.33 | |
| Nurix Therapeutics (NRIX) | 0.3 | $76M | 2.5M | 31.09 | |
| Kymera Therapeutics (KYMR) | 0.3 | $76M | 2.0M | 38.86 | |
| Rhythm Pharmaceuticals (RYTM) | 0.3 | $74M | 3.5M | 21.27 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.3 | $73M | 2.2M | 34.06 | |
| Apellis Pharmaceuticals (APLS) | 0.3 | $72M | 1.7M | 42.91 | |
| Neurocrine Biosciences (NBIX) | 0.3 | $66M | 677k | 97.25 | |
| Krystal Biotech (KRYS) | 0.3 | $59M | 760k | 77.04 | |
| Forma Therapeutics Holdings SHS | 0.2 | $57M | 2.0M | 28.02 | |
| Horizon Therapeutics Public SHS | 0.2 | $55M | 599k | 92.04 | |
| Atreca Cl A Com (BCEL) | 0.2 | $54M | 3.5M | 15.33 | |
| Zymeworks | 0.2 | $54M | 1.7M | 31.58 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.2 | $52M | 9.8M | 5.31 | |
| Kiniksa Pharmaceuticals Com Cl A | 0.2 | $52M | 2.8M | 18.51 | |
| Ultragenyx Pharmaceutical (RARE) | 0.2 | $51M | 444k | 113.86 | |
| Neoleukin Therapeutics | 0.2 | $47M | 3.8M | 12.31 | |
| Immatics SHS (IMTX) | 0.2 | $45M | 4.0M | 11.21 | |
| Design Therapeutics (DSGN) | 0.2 | $43M | 1.4M | 29.90 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.2 | $43M | 2.6M | 16.55 | |
| Merus N V (MRUS) | 0.2 | $43M | 2.0M | 20.89 | |
| Verastem | 0.2 | $42M | 17M | 2.47 | |
| Bioatla (BCAB) | 0.2 | $42M | 825k | 50.84 | |
| Altimmune (ALT) | 0.2 | $39M | 2.8M | 14.13 | |
| Fulgent Genetics (FLGT) | 0.2 | $39M | 401k | 96.62 | |
| Protagonist Therapeutics (PTGX) | 0.2 | $37M | 1.4M | 25.90 | |
| Aligos Therapeutics (ALGS) | 0.2 | $37M | 1.6M | 22.74 | |
| Axsome Therapeutics (AXSM) | 0.2 | $36M | 628k | 56.62 | |
| ADC Therapeutics SA SHS (ADCT) | 0.2 | $35M | 1.4M | 24.41 | |
| Chemocentryx | 0.1 | $34M | 657k | 51.24 | |
| Opthea Sponsored Ads (OPT) | 0.1 | $32M | 3.3M | 9.57 | |
| Aeglea Biotherapeutics | 0.1 | $27M | 3.4M | 7.92 | |
| Novavax (NVAX) | 0.1 | $26M | 144k | 181.31 | |
| Alkermes SHS (ALKS) | 0.1 | $23M | 1.2M | 18.68 | |
| Mereo BioPharma Group Ads (MREO) | 0.1 | $23M | 6.7M | 3.37 | |
| Reata Pharmaceuticals Cl A | 0.1 | $22M | 224k | 99.70 | |
| Otonomy | 0.1 | $18M | 7.2M | 2.55 | |
| Aurinia Pharmaceuticals (AUPH) | 0.1 | $18M | 1.4M | 12.99 | |
| Edgewise Therapeutics (EWTX) | 0.1 | $16M | 500k | 32.50 | |
| Xencor (XNCR) | 0.1 | $16M | 369k | 43.06 | |
| Invitae Corporation Note 2.0% 9/1/2024 (Principal) | 0.1 | $16M | 10M | 1.51 | |
| BioMarin Pharmaceutical Note 0.599% 8/1/2024 (Principal) | 0.1 | $15M | 15M | 1.02 | |
| Athira Pharma (ATHA) | 0.1 | $15M | 806k | 18.40 | |
| Albireo Pharma | 0.1 | $15M | 413k | 35.25 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $14M | 752k | 17.90 | |
| Mirum Pharmaceuticals (MIRM) | 0.1 | $13M | 647k | 19.82 | |
| Sarepta Therapeutics DBCV 1.5% 11/15/2024 (Principal) | 0.1 | $12M | 9.2M | 1.30 | |
| Chinook Therapeutics | 0.1 | $12M | 749k | 15.54 | |
| Silverback Therapeutics (SPRY) | 0.0 | $10M | 238k | 43.63 | |
| Revolution Medicines (RVMD) | 0.0 | $10M | 222k | 45.88 | |
| Cymabay Therapeutics | 0.0 | $9.9M | 2.2M | 4.54 | |
| Genetron Holdings Ads | 0.0 | $9.8M | 455k | 21.46 | |
| Hookipa Pharma Inc equity | 0.0 | $9.4M | 701k | 13.45 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.0 | $9.4M | 617k | 15.28 | |
| Anaptysbio Inc Common (ANAB) | 0.0 | $9.2M | 427k | 21.55 | |
| Iveric Bio | 0.0 | $8.7M | 1.4M | 6.18 | |
| Ngm Biopharmaceuticals | 0.0 | $8.5M | 292k | 29.07 | |
| Karuna Therapeutics Ord | 0.0 | $8.4M | 70k | 120.23 | |
| Gamida Cell SHS | 0.0 | $8.4M | 1.0M | 8.09 | |
| Assembly Biosciences | 0.0 | $7.1M | 1.5M | 4.60 | |
| Cabaletta Bio (CABA) | 0.0 | $7.1M | 636k | 11.10 | |
| Bluebird Bio (BLUE) | 0.0 | $6.8M | 227k | 30.15 | |
| Macrogenics (MGNX) | 0.0 | $6.4M | 201k | 31.85 | |
| Burning Rock Biotech Sponsored Ads | 0.0 | $5.6M | 209k | 26.92 | |
| Neximmune | 0.0 | $5.6M | 294k | 19.08 | |
| Sangamo Biosciences (SGMO) | 0.0 | $5.4M | 429k | 12.53 | |
| Orchard Therapeutics Ads | 0.0 | $5.3M | 734k | 7.26 | |
| Syros Pharmaceuticals | 0.0 | $5.2M | 690k | 7.48 | |
| Iteos Therapeutics (ITOS) | 0.0 | $5.1M | 150k | 34.18 | |
| Denali Therapeutics (DNLI) | 0.0 | $5.1M | 89k | 57.10 | |
| Alector (ALEC) | 0.0 | $4.8M | 239k | 20.14 | |
| Evofem Biosciences | 0.0 | $4.7M | 2.7M | 1.75 | |
| Replimune Group (REPL) | 0.0 | $4.7M | 154k | 30.51 | |
| Travere Therapeutics (TVTX) | 0.0 | $4.7M | 187k | 24.97 | |
| Sarepta Therapeutics (SRPT) | 0.0 | $4.4M | 59k | 74.53 | |
| Passage Bio (PASG) | 0.0 | $4.1M | 235k | 17.48 | |
| Harmony Biosciences Hldgs In (HRMY) | 0.0 | $4.1M | 124k | 33.04 | |
| Tcr2 Therapeutics Inc cs | 0.0 | $3.9M | 177k | 22.08 | |
| Tricida | 0.0 | $3.9M | 729k | 5.29 | |
| Akero Therapeutics (AKRO) | 0.0 | $3.4M | 118k | 29.01 | |
| Legend Biotech Corporation Sponsored Ads (LEGN) | 0.0 | $3.4M | 116k | 29.02 | |
| Logicbio Therapeutics | 0.0 | $3.3M | 452k | 7.28 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $3.1M | 200k | 15.74 | |
| Acceleron Pharma | 0.0 | $3.0M | 22k | 135.62 | |
| Constellation Pharmceticls I | 0.0 | $2.7M | 115k | 23.39 | |
| Idera Pharmaceuticals Com Par | 0.0 | $2.7M | 2.0M | 1.30 | |
| Autolus Therapeutics Sponsored Ads (AUTL) | 0.0 | $2.6M | 462k | 5.73 | |
| Chiasma | 0.0 | $2.3M | 742k | 3.13 | |
| Viking Therapeutics (VKTX) | 0.0 | $2.3M | 364k | 6.32 | |
| Inozyme Pharma (INZY) | 0.0 | $2.1M | 107k | 19.80 | |
| Molecular Templates | 0.0 | $1.7M | 134k | 12.62 | |
| Affimed Therapeutics B V | 0.0 | $1.3M | 165k | 7.91 | |
| Oyster Point Pharma | 0.0 | $1.1M | 61k | 18.28 | |
| Leap Therapeutics | 0.0 | $1.1M | 560k | 1.90 | |
| Bellicum Pharmaceuticals | 0.0 | $937k | 249k | 3.76 | |
| Galapagos NV Sponsored Adr (GLPG) | 0.0 | $862k | 11k | 77.10 | |
| Kezar Life Sciences (KZR) | 0.0 | $832k | 140k | 5.96 | |
| Adamas Pharmaceuticals | 0.0 | $710k | 148k | 4.80 | |
| Galmed Pharmaceuticals SHS | 0.0 | $634k | 185k | 3.43 | |
| Inflarx Nv (IFRX) | 0.0 | $538k | 138k | 3.90 | |
| Frequency Therapeutics | 0.0 | $528k | 56k | 9.50 | |
| Genfit SA Ads (GNFT) | 0.0 | $68k | 15k | 4.62 |
