Baker Bros. Advisors

Baker Bros. Advisors as of June 30, 2021

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 120 positions in its portfolio as reported in the June 2021 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seagen 32.8 $7.5B 47M 157.88
BeiGene Sponsored Adr (ONC) 17.6 $4.0B 12M 343.19
Incyte Corporation (INCY) 11.8 $2.7B 32M 84.13
Kodiak Sciences (KOD) 5.8 $1.3B 14M 93.00
ACADIA Pharmaceuticals (ACAD) 4.5 $1.0B 42M 24.39
BioMarin Pharmaceutical (BMRN) 2.8 $633M 7.6M 83.44
Ascendis Pharma A/S Sponsored Adr 2.0 $466M 3.5M 131.55
Invitae (NVTAQ) 1.5 $346M 10M 33.73
argenx SE Sponsored Adr (ARGX) 1.5 $337M 1.1M 301.07
Prelude Therapeutics (PRLD) 1.3 $290M 10M 28.63
Igm Biosciences (IGMS) 1.2 $263M 3.2M 83.20
Abcellera Biologics (ABCL) 1.0 $230M 11M 22.00
Mirati Therapeutics 1.0 $228M 1.4M 161.53
BioCryst Pharmaceuticals (BCRX) 0.9 $201M 13M 15.81
Madrigal Pharmaceuticals (MDGL) 0.6 $146M 1.5M 97.41
Apellis Pharmaceuticals 0.6 $144M 2.3M 63.20
Heron Therapeutics (HRTX) 0.6 $126M 8.1M 15.52
Amarin Corporation Sponsored Adr 0.5 $116M 27M 4.38
Global Blood Therapeutics In 0.5 $113M 3.2M 35.02
Pacific Biosciences of California (PACB) 0.5 $112M 3.2M 34.97
Immunocore Holdings Ads (IMCR) 0.4 $98M 2.5M 39.05
Kymera Therapeutics (KYMR) 0.4 $95M 2.0M 48.50
Verastem 0.4 $88M 22M 4.07
Verve Therapeutics (VERV) 0.4 $85M 1.4M 60.25
Talis Biomedical Corp 0.4 $84M 7.6M 11.03
Cerus Corporation (CERS) 0.4 $81M 14M 5.91
DBV Technologies Sponsored Adr 0.4 $80M 15M 5.46
Rhythm Pharmaceuticals (RYTM) 0.3 $76M 3.9M 19.58
Instil Bio 0.3 $75M 3.9M 19.32
Legend Biotech Corporation Sponsored Ads (LEGN) 0.3 $68M 1.7M 41.05
Neurocrine Biosciences (NBIX) 0.3 $66M 677k 97.32
Nurix Therapeutics (NRIX) 0.3 $65M 2.5M 26.53
Insmed Incorporated Com Par $.01 (INSM) 0.3 $61M 2.2M 28.46
Allakos 0.3 $60M 703k 85.37
Zymeworks 0.3 $59M 1.7M 34.69
Horizon Therapeutics Public SHS 0.2 $56M 599k 93.64
Forma Therapeutics Holdings SHS 0.2 $50M 2.0M 24.89
Immatics SHS (IMTX) 0.2 $50M 4.3M 11.61
Insmed Incorporated Note 0.75% 6/1/2028 (Principal) 0.2 $44M 40M 1.10
Merus N V (MRUS) 0.2 $43M 2.0M 21.07
Ultragenyx Pharmaceutical (RARE) 0.2 $42M 444k 95.35
Adaptimmune Therapeutics Sponsored Adr (ADAPY) 0.2 $42M 9.8M 4.26
Krystal Biotech (KRYS) 0.2 $41M 608k 68.00
Kiniksa Pharmaceuticals Com Cl A 0.2 $39M 2.8M 13.93
Sarepta Therapeutics DBCV 1.5% 11/15/2024 (Principal) 0.2 $39M 29M 1.32
Fulgent Genetics (FLGT) 0.2 $37M 401k 92.23
Axsome Therapeutics (AXSM) 0.2 $36M 539k 67.46
Neoleukin Therapeutics 0.2 $35M 3.8M 9.23
Bioatla 0.2 $35M 825k 42.38
ADC Therapeutics SA SHS (ADCT) 0.2 $35M 1.4M 24.35
Aligos Therapeutics 0.1 $33M 1.6M 20.39
Aerovate Therapeutics (AVTE) 0.1 $33M 1.4M 22.83
Reata Pharmaceuticals Cl A 0.1 $32M 224k 141.53
Novavax (NVAX) 0.1 $31M 144k 212.31
Alkermes SHS (ALKS) 0.1 $30M 1.2M 24.52
Atreca Cl A Com (BCEL) 0.1 $30M 3.5M 8.52
Design Therapeutics (DSGN) 0.1 $29M 1.4M 19.89
Apellis Pharmaceuticals Note 3.5% 9/15/2026 (Principal) 0.1 $28M 15M 1.85
Tricida Note 3.5% 5/15/2027 (Principal) 0.1 $27M 75M 0.36
Opthea Sponsored Ads (OPTEY) 0.1 $27M 3.4M 7.94
Achilles Therapeutics Sponsored Ads (ACHL) 0.1 $25M 2.6M 9.79
Aeglea Biotherapeutics 0.1 $24M 3.4M 6.96
Protagonist Therapeutics (PTGX) 0.1 $20M 455k 44.88
Cyteir Therapeutics 0.1 $17M 813k 21.40
Crinetics Pharmaceuticals In (CRNX) 0.1 $17M 921k 18.85
Otonomy 0.1 $16M 7.2M 2.23
BioMarin Pharmaceutical Note 0.599% 8/1/2024 (Principal) 0.1 $16M 15M 1.04
Chinook Therapeutics 0.1 $15M 1.1M 14.12
Aurinia Pharmaceuticals (AUPH) 0.1 $15M 1.1M 12.96
Albireo Pharma 0.1 $15M 413k 35.18
Xenon Pharmaceuticals (XENE) 0.1 $14M 752k 18.62
Invitae Corporation Note 2.0% 9/1/2024 (Principal) 0.1 $14M 10M 1.35
Mirum Pharmaceuticals (MIRM) 0.0 $11M 647k 17.29
Anaptysbio Inc Common (ANAB) 0.0 $11M 427k 25.93
Edgewise Therapeutics (EWTX) 0.0 $11M 500k 21.33
Altimmune (ALT) 0.0 $11M 1.1M 9.85
Cymabay Therapeutics 0.0 $9.5M 2.2M 4.36
Genetron Holdings Ads 0.0 $9.2M 455k 20.14
Centessa Pharmaceuticals Sponsored Ads 0.0 $8.9M 400k 22.21
Iveric Bio 0.0 $8.9M 1.4M 6.31
Athira Pharma (ATHA) 0.0 $8.3M 806k 10.24
Assembly Biosciences 0.0 $8.2M 2.1M 3.88
Karuna Therapeutics Ord 0.0 $8.0M 70k 113.98
Mereo BioPharma Group Ads (MREO) 0.0 $7.8M 2.5M 3.17
Silverback Therapeutics (SPRY) 0.0 $7.4M 238k 30.89
Bluebird Bio 0.0 $7.3M 227k 31.98
Revolution Medicines (RVMD) 0.0 $7.1M 222k 31.74
Denali Therapeutics (DNLI) 0.0 $7.0M 89k 78.44
Chiasma 0.0 $6.7M 1.4M 4.73
Hookipa Pharma Inc equity 0.0 $6.4M 701k 9.16
Burning Rock Biotech Sponsored Ads 0.0 $6.2M 209k 29.46
Replimune Group (REPL) 0.0 $5.9M 154k 38.42
Ngm Biopharmaceuticals 0.0 $5.8M 292k 19.72
Cabaletta Bio (CABA) 0.0 $5.5M 636k 8.60
Macrogenics (MGNX) 0.0 $5.4M 201k 26.86
Orchard Therapeutics Ads 0.0 $5.2M 1.2M 4.39
Alector (ALEC) 0.0 $5.0M 239k 20.83
Neximmune 0.0 $4.8M 294k 16.32
Biomea Fusion (BMEA) 0.0 $4.6M 294k 15.61
Gamida Cell SHS 0.0 $3.9M 611k 6.41
Iteos Therapeutics 0.0 $3.9M 150k 25.65
Harmony Biosciences Hldgs In (HRMY) 0.0 $3.5M 124k 28.23
Tricida 0.0 $3.2M 729k 4.32
Evofem Biosciences 0.0 $3.0M 2.7M 1.13
Akero Therapeutics (AKRO) 0.0 $2.9M 118k 24.81
Tcr2 Therapeutics Inc cs 0.0 $2.9M 177k 16.41
Acceleron Pharma 0.0 $2.8M 22k 125.50
Travere Therapeutics (TVTX) 0.0 $2.7M 187k 14.59
Relmada Therapeutics (RLMD) 0.0 $2.5M 77k 32.01
Logicbio Therapeutics 0.0 $2.0M 452k 4.44
Protara Therapeutics Com Stk (TARA) 0.0 $1.9M 200k 9.74
Inozyme Pharma (INZY) 0.0 $1.8M 107k 17.04
Passage Bio 0.0 $1.6M 117k 13.24
Affimed Therapeutics B V 0.0 $1.4M 165k 8.50
Oyster Point Pharma 0.0 $1.1M 61k 17.19
Leap Therapeutics 0.0 $918k 560k 1.64
Bellicum Pharmaceuticals 0.0 $822k 249k 3.30
Kezar Life Sciences 0.0 $758k 140k 5.43
Frequency Therapeutics 0.0 $553k 56k 9.95
Syros Pharmaceuticals 0.0 $357k 66k 5.45