Baker Bros. Advisors

Baker Bros. Advisors as of Sept. 30, 2021

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 122 positions in its portfolio as reported in the September 2021 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seagen 35.3 $8.0B 47M 169.80
BeiGene Sponsored Adr (BGNE) 18.6 $4.2B 12M 363.00
Incyte Corporation (INCY) 9.7 $2.2B 32M 68.78
Kodiak Sciences (KOD) 6.2 $1.4B 15M 95.98
Ascendis Pharma A/S Sponsored Adr (ASND) 3.2 $724M 4.5M 159.39
ACADIA Pharmaceuticals (ACAD) 3.1 $696M 42M 16.61
BioMarin Pharmaceutical (BMRN) 2.6 $589M 7.6M 77.29
argenx SE Sponsored Adr (ARGX) 1.5 $338M 1.1M 302.00
Prelude Therapeutics (PRLD) 1.4 $316M 10M 31.25
Invitae (NVTAQ) 1.2 $281M 9.9M 28.43
Mirati Therapeutics 1.1 $249M 1.4M 176.91
Abcellera Biologics (ABCL) 0.9 $209M 11M 20.04
Igm Biosciences (IGMS) 0.9 $208M 3.2M 65.76
BioCryst Pharmaceuticals (BCRX) 0.8 $183M 13M 14.37
Kymera Therapeutics (KYMR) 0.6 $140M 2.4M 58.74
Pacific Biosciences of California (PACB) 0.6 $139M 5.4M 25.55
Madrigal Pharmaceuticals (MDGL) 0.5 $120M 1.5M 79.79
Legend Biotech Corporation Sponsored Ads (LEGN) 0.5 $120M 2.4M 50.56
Amarin Corporation Sponsored Adr (AMRN) 0.5 $112M 22M 5.10
Immunocore Holdings Ads (IMCR) 0.4 $93M 2.5M 37.07
Heron Therapeutics (HRTX) 0.4 $87M 8.1M 10.69
Cerus Corporation (CERS) 0.4 $84M 14M 6.09
Global Blood Therapeutics In 0.4 $82M 3.2M 25.48
Allakos (ALLK) 0.3 $74M 703k 105.87
Nurix Therapeutics (NRIX) 0.3 $74M 2.5M 29.96
DBV Technologies Sponsored Adr 0.3 $72M 15M 4.90
Instil Bio 0.3 $70M 3.9M 17.88
Verve Therapeutics (VERV) 0.3 $67M 1.4M 47.00
Verastem 0.3 $66M 22M 3.08
Horizon Therapeutics Public SHS 0.3 $66M 599k 109.54
Neurocrine Biosciences (NBIX) 0.3 $65M 677k 95.91
Insmed Incorporated Com Par $.01 (INSM) 0.3 $59M 2.2M 27.54
Immatics SHS (IMTX) 0.3 $58M 4.4M 13.00
Apellis Pharmaceuticals Note 3.5% 9/15/2026 (Principal) 0.3 $57M 47M 1.22
Adaptimmune Therapeutics Sponsored Adr (ADAP) 0.2 $51M 9.8M 5.17
Rhythm Pharmaceuticals (RYTM) 0.2 $51M 3.9M 13.06
Zymeworks 0.2 $50M 1.7M 29.04
Travere Therapeutics (TVTX) 0.2 $50M 2.0M 24.25
Bluebird Bio (BLUE) 0.2 $48M 2.5M 19.11
Talis Biomedical Corp 0.2 $47M 7.6M 6.25
Forma Therapeutics Holdings SHS 0.2 $47M 2.0M 23.19
Merus N V (MRUS) 0.2 $45M 2.0M 22.00
Insmed Incorporated Note 0.75% 6/1/2028 (Principal) 0.2 $44M 40M 1.10
Sarepta Therapeutics DBCV 1.5% 11/15/2024 (Principal) 0.2 $43M 29M 1.48
Ultragenyx Pharmaceutical (RARE) 0.2 $40M 444k 90.19
Alkermes SHS (ALKS) 0.2 $38M 1.2M 30.84
Fulgent Genetics (FLGT) 0.2 $36M 401k 89.95
Aerovate Therapeutics (AVTE) 0.2 $35M 1.7M 20.98
Aligos Therapeutics (ALGS) 0.1 $32M 2.1M 15.51
Kiniksa Pharmaceuticals Com Cl A 0.1 $32M 2.8M 11.39
Krystal Biotech (KRYS) 0.1 $32M 608k 52.21
Tricida Note 3.5% 5/15/2027 (Principal) 0.1 $31M 75M 0.42
Neoleukin Therapeutics 0.1 $28M 3.8M 7.23
Aeglea Biotherapeutics 0.1 $27M 3.4M 7.95
Opthea Sponsored Ads (OPT) 0.1 $27M 3.4M 8.00
Bioatla (BCAB) 0.1 $24M 825k 29.44
Chinook Therapeutics 0.1 $24M 1.9M 12.76
Novavax (NVAX) 0.1 $23M 109k 207.31
Reata Pharmaceuticals Cl A 0.1 $23M 224k 100.61
Atreca Cl A Com (BCEL) 0.1 $22M 3.5M 6.23
Design Therapeutics (DSGN) 0.1 $21M 1.4M 14.69
Achilles Therapeutics Sponsored Ads (ACHL) 0.1 $20M 2.6M 7.79
Crinetics Pharmaceuticals In (CRNX) 0.1 $19M 921k 21.05
Dice Therapeutics 0.1 $19M 588k 32.75
Centessa Pharmaceuticals Sponsored Ads (CNTA) 0.1 $19M 1.1M 16.70
Axsome Therapeutics (AXSM) 0.1 $18M 539k 32.96
Surrozen 0.1 $18M 2.5M 7.08
Otonomy 0.1 $15M 7.7M 1.92
Cyteir Therapeutics 0.1 $14M 813k 17.55
Mirum Pharmaceuticals (MIRM) 0.1 $13M 647k 19.92
Albireo Pharma 0.1 $13M 413k 31.20
Invitae Corporation Note 2.0% 9/1/2024 (Principal) 0.1 $13M 10M 1.22
Altimmune (ALT) 0.1 $12M 1.1M 11.31
Tscan Therapeutics (TCRX) 0.1 $12M 1.4M 8.34
Anaptysbio Inc Common (ANAB) 0.1 $12M 427k 27.12
Aurinia Pharmaceuticals (AUPH) 0.1 $12M 521k 22.13
Xenon Pharmaceuticals (XENE) 0.1 $12M 752k 15.28
Tango Therapeutics (TNGX) 0.0 $9.7M 750k 12.93
Macrogenics (MGNX) 0.0 $9.3M 443k 20.94
Karuna Therapeutics Ord 0.0 $8.6M 70k 122.33
Edgewise Therapeutics (EWTX) 0.0 $8.3M 500k 16.60
Cabaletta Bio (CABA) 0.0 $8.1M 662k 12.16
Cymabay Therapeutics 0.0 $7.9M 2.2M 3.65
Athira Pharma (ATHA) 0.0 $7.6M 806k 9.38
Genetron Holdings Ads 0.0 $6.3M 455k 13.85
Biomea Fusion (BMEA) 0.0 $6.3M 525k 11.97
Amryt Pharma Sponsored Adr 0.0 $6.2M 518k 12.05
Ngm Biopharmaceuticals 0.0 $6.1M 292k 21.02
Revolution Medicines (RVMD) 0.0 $6.1M 222k 27.51
Kura Oncology (KURA) 0.0 $5.7M 304k 18.73
Atyr Pharma (ATYR) 0.0 $5.7M 625k 9.08
Alector (ALEC) 0.0 $5.5M 239k 22.82
Relmada Therapeutics (RLMD) 0.0 $5.3M 201k 26.21
Chemocentryx 0.0 $5.2M 301k 17.10
Tricida 0.0 $4.8M 1.0M 4.64
Harmony Biosciences Hldgs In (HRMY) 0.0 $4.7M 124k 38.33
BioMarin Pharmaceutical Note 0.599% 8/1/2024 (Principal) 0.0 $4.6M 4.5M 1.02
Replimune Group (REPL) 0.0 $4.6M 154k 29.64
Denali Therapeutics (DNLI) 0.0 $4.5M 89k 50.45
Neximmune 0.0 $4.5M 294k 15.14
Hookipa Pharma Inc equity 0.0 $4.1M 701k 5.89
Iteos Therapeutics (ITOS) 0.0 $4.1M 150k 27.00
Vincera Pharma (VINC) 0.0 $3.9M 241k 16.17
Acceleron Pharma 0.0 $3.9M 22k 172.09
Burning Rock Biotech Sponsored Ads 0.0 $3.7M 209k 17.88
Akero Therapeutics (AKRO) 0.0 $2.6M 118k 22.35
Gamida Cell SHS 0.0 $2.4M 611k 3.92
Leap Therapeutics 0.0 $2.2M 560k 4.01
Sera Prognostics Class A Com (SERA) 0.0 $2.2M 202k 11.11
Syndax Pharmaceuticals (SNDX) 0.0 $2.1M 111k 19.11
Logicbio Therapeutics 0.0 $2.1M 452k 4.58
Evofem Biosciences 0.0 $2.0M 2.7M 0.74
Tcr2 Therapeutics Inc cs 0.0 $1.5M 177k 8.51
Protara Therapeutics Com Stk (TARA) 0.0 $1.4M 200k 6.92
Inozyme Pharma (INZY) 0.0 $1.2M 107k 11.59
Kezar Life Sciences (KZR) 0.0 $1.2M 140k 8.64
Passage Bio (PASG) 0.0 $1.2M 117k 9.96
Affimed Therapeutics B V 0.0 $1.0M 165k 6.18
Surrozen W Exp 8/11/2026 (SRZNW) 0.0 $950k 833k 1.14
Oyster Point Pharma 0.0 $728k 61k 11.85
Bellicum Pharmaceuticals 0.0 $727k 249k 2.92
Mereo BioPharma Group Ads (MREO) 0.0 $708k 293k 2.42