Spdr S&p 500 Etf Tr Tr Unit Put Option
(SPY)
|
9.1 |
$129M |
|
300k |
429.14 |
Spdr Ser Tr S&p Biotech Put Option
(XBI)
|
8.4 |
$119M |
|
950k |
125.71 |
Celldex Therapeutics Com New Put Option
(CLDX)
|
6.0 |
$85M |
|
1.6M |
53.99 |
Reata Pharmaceuticals Cl A Call Option
|
4.1 |
$59M |
|
581k |
100.61 |
Biogen Idec
(BIIB)
|
4.0 |
$57M |
|
200k |
282.95 |
Horizon Therapeutics Pub L SHS
|
3.5 |
$49M |
|
448k |
109.54 |
UnitedHealth Call Option
(UNH)
|
2.8 |
$39M |
|
100k |
390.74 |
Alnylam Pharmaceuticals
(ALNY)
|
2.4 |
$34M |
|
181k |
188.91 |
Sarepta Therapeutics
(SRPT)
|
2.4 |
$34M |
|
368k |
92.67 |
Compass Pathways Sponsored Ads
(CMPS)
|
2.3 |
$32M |
|
1.1M |
29.87 |
Rafael Hldgs Com Cl B Put Option
(RFL)
|
2.2 |
$31M |
|
994k |
30.73 |
Apellis Pharmaceuticals Put Option
(APLS)
|
2.1 |
$31M |
|
926k |
32.96 |
Krystal Biotech Call Option
(KRYS)
|
2.1 |
$30M |
|
575k |
52.21 |
Bicycle Therapeutics Sponsored Ads
(BCYC)
|
1.9 |
$27M |
|
657k |
41.59 |
Crispr Therapeutics Namen Akt Put Option
(CRSP)
|
1.8 |
$25M |
|
225k |
111.93 |
Allakos Put Option
(ALLK)
|
1.6 |
$23M |
|
220k |
105.88 |
Chemocentryx Call Option
|
1.4 |
$21M |
|
1.2M |
17.10 |
Zentalis Pharmaceuticals
(ZNTL)
|
1.4 |
$20M |
|
292k |
66.62 |
Gossamer Bio
(GOSS)
|
1.4 |
$19M |
|
1.5M |
12.57 |
Xenon Pharmaceuticals Call Option
(XENE)
|
1.2 |
$18M |
|
1.2M |
15.28 |
Kodiak Sciences Call Option
(KOD)
|
1.1 |
$16M |
|
168k |
95.98 |
Cortexyme Call Option
(QNCX)
|
1.0 |
$15M |
|
162k |
91.65 |
Novavax Com New Call Option
(NVAX)
|
1.0 |
$15M |
|
71k |
207.30 |
Cabaletta Bio
(CABA)
|
1.0 |
$14M |
|
1.2M |
12.16 |
X4 Pharmaceuticals
(XFOR)
|
0.9 |
$13M |
|
2.5M |
5.29 |
Macrogenics Call Option
(MGNX)
|
0.9 |
$13M |
|
635k |
20.94 |
Mirati Therapeutics Put Option
|
0.9 |
$13M |
|
71k |
177.69 |
Sierra Oncology Com New
|
0.9 |
$13M |
|
573k |
21.92 |
Editas Medicine Put Option
(EDIT)
|
0.9 |
$13M |
|
304k |
41.08 |
Immatics SHS
(IMTX)
|
0.8 |
$12M |
|
883k |
13.00 |
Merck & Co Call Option
(MRK)
|
0.8 |
$11M |
|
150k |
75.11 |
Amicus Therapeutics Call Option
(FOLD)
|
0.8 |
$11M |
|
1.1M |
9.55 |
Tracon Pharmaceuticals Com New
|
0.7 |
$10M |
|
2.7M |
3.87 |
Milestone Pharmaceuticals
(MIST)
|
0.7 |
$10M |
|
1.8M |
5.71 |
Igm Biosciences Call Option
(IGMS)
|
0.7 |
$10M |
|
152k |
65.76 |
Dicerna Pharmaceuticals Call Option
|
0.7 |
$10M |
|
494k |
20.16 |
Inhibrx
|
0.7 |
$9.7M |
|
290k |
33.31 |
Iovance Biotherapeutics Put Option
(IOVA)
|
0.6 |
$9.1M |
|
369k |
24.66 |
Incyte Corporation Call Option
(INCY)
|
0.6 |
$9.0M |
|
131k |
68.78 |
Zogenix Com New Call Option
|
0.6 |
$9.0M |
|
590k |
15.19 |
Arena Pharmaceuticals Com New Call Option
|
0.6 |
$8.9M |
|
149k |
59.54 |
Intra Cellular Therapies
(ITCI)
|
0.6 |
$7.9M |
|
212k |
37.27 |
Ocular Therapeutix Call Option
(OCUL)
|
0.5 |
$7.7M |
|
771k |
10.00 |
Vaxcyte
(PCVX)
|
0.5 |
$7.5M |
|
295k |
25.37 |
Iveric Bio
|
0.5 |
$6.8M |
|
417k |
16.24 |
Elanco Animal Health Call Option
(ELAN)
|
0.4 |
$6.4M |
|
200k |
31.89 |
Ayala Pharmaceuticals Incorporated
|
0.4 |
$6.1M |
|
539k |
11.34 |
Astrazeneca Sponsored Adr Call Option
(AZN)
|
0.4 |
$6.0M |
|
100k |
60.06 |
Scpharmaceuticals
(SCPH)
|
0.4 |
$6.0M |
|
901k |
6.65 |
Fate Therapeutics Put Option
(FATE)
|
0.4 |
$5.9M |
|
100k |
59.28 |
Bioatla
(BCAB)
|
0.4 |
$5.8M |
|
196k |
29.44 |
Odonate Therapeutics Ord
|
0.4 |
$5.4M |
|
1.8M |
2.91 |
Aldeyra Therapeutics Call Option
(ALDX)
|
0.4 |
$5.3M |
|
600k |
8.78 |
Atyr Pharma Com New
(ATYR)
|
0.4 |
$5.1M |
|
562k |
9.08 |
Relay Therapeutics Put Option
(RLAY)
|
0.4 |
$5.0M |
|
160k |
31.52 |
Clovis Oncology
|
0.3 |
$5.0M |
|
1.1M |
4.46 |
Chimerix
(CMRX)
|
0.3 |
$5.0M |
|
801k |
6.19 |
Atea Pharmaceuticals Call Option
(AVIR)
|
0.3 |
$4.9M |
|
139k |
35.06 |
Wave Life Sciences SHS
(WVE)
|
0.3 |
$4.9M |
|
994k |
4.90 |
ACADIA Pharmaceuticals
(ACAD)
|
0.3 |
$4.7M |
|
282k |
16.61 |
Bellus Health Com New
|
0.3 |
$4.6M |
|
745k |
6.14 |
Galapagos Nv Spon Adr
(GLPG)
|
0.3 |
$4.5M |
|
87k |
52.31 |
Aurinia Pharmaceuticals Call Option
(AUPH)
|
0.3 |
$4.4M |
|
200k |
22.13 |
Seres Therapeutics
(MCRB)
|
0.3 |
$4.2M |
|
607k |
6.96 |
Finch Therapeutics
|
0.3 |
$4.1M |
|
316k |
13.00 |
Renovacor
|
0.3 |
$4.0M |
|
443k |
9.05 |
Verastem
|
0.3 |
$3.8M |
|
1.2M |
3.08 |
Ovid Therapeutics
(OVID)
|
0.3 |
$3.7M |
|
1.1M |
3.36 |
Lyra Therapeutics
(LYRA)
|
0.3 |
$3.7M |
|
404k |
9.14 |
Corvus Pharmaceuticals
(CRVS)
|
0.3 |
$3.7M |
|
758k |
4.84 |
BioCryst Pharmaceuticals Call Option
(BCRX)
|
0.3 |
$3.6M |
|
250k |
14.37 |
Autolus Therapeutics Spon Ads
(AUTL)
|
0.3 |
$3.6M |
|
545k |
6.55 |
Trillium Therapeutics Com New Call Option
|
0.2 |
$3.5M |
|
198k |
17.56 |
Nextcure
(NXTC)
|
0.2 |
$3.4M |
|
509k |
6.74 |
Clene Common Stock
(CLNN)
|
0.2 |
$3.3M |
|
489k |
6.83 |
Protara Therapeutics Com Stk
(TARA)
|
0.2 |
$3.3M |
|
480k |
6.92 |
Tg Therapeutics Put Option
(TGTX)
|
0.2 |
$3.3M |
|
99k |
33.29 |
Vincerx Pharma Com New
(VINC)
|
0.2 |
$3.2M |
|
199k |
16.17 |
Phathom Pharmaceuticals
(PHAT)
|
0.2 |
$3.2M |
|
100k |
32.10 |
Chemomab Therapeutics Sponsored Ads
(CMMB)
|
0.2 |
$3.2M |
|
285k |
11.08 |
Viking Therapeutics
(VKTX)
|
0.2 |
$3.1M |
|
501k |
6.28 |
Tricida
|
0.2 |
$3.1M |
|
671k |
4.64 |
Dbv Technologies S A Sponsored Adr
|
0.2 |
$3.1M |
|
310k |
10.03 |
Adicet Bio
(ACET)
|
0.2 |
$3.1M |
|
392k |
7.84 |
Ark Etf Tr Genomic Rev Etf
(ARKG)
|
0.2 |
$3.1M |
|
41k |
74.73 |
Satsuma Pharmaceuticals Ord
|
0.2 |
$2.9M |
|
629k |
4.66 |
Aileron Therapeutics
|
0.2 |
$2.8M |
|
2.8M |
1.02 |
Sutro Biopharma
(STRO)
|
0.2 |
$2.5M |
|
135k |
18.88 |
Liquidia Corporation Com New
(LQDA)
|
0.2 |
$2.4M |
|
885k |
2.76 |
Synaptogenix Com New
|
0.2 |
$2.4M |
|
246k |
9.94 |
Synlogic
|
0.2 |
$2.4M |
|
789k |
3.05 |
Yumanity Therapeutics
|
0.2 |
$2.4M |
|
229k |
10.32 |
Eledon Pharmaceuticals
(ELDN)
|
0.1 |
$2.1M |
|
345k |
6.18 |
Savara
(SVRA)
|
0.1 |
$2.1M |
|
1.5M |
1.38 |
Nektar Therapeutics Call Option
(NKTR)
|
0.1 |
$2.1M |
|
115k |
17.96 |
Codiak Biosciences
|
0.1 |
$2.0M |
|
120k |
16.33 |
Health Sciences Acq Corp 2 Ord Shs
|
0.1 |
$2.0M |
|
197k |
9.89 |
Madrigal Pharmaceuticals
(MDGL)
|
0.1 |
$1.9M |
|
24k |
79.75 |
Catalyst Biosciences Com New
|
0.1 |
$1.9M |
|
454k |
4.11 |
Maxcyte
(MXCT)
|
0.1 |
$1.8M |
|
150k |
12.21 |
Gemini Therapeutics
|
0.1 |
$1.7M |
|
421k |
4.04 |
Kalvista Pharmaceuticals
(KALV)
|
0.1 |
$1.7M |
|
97k |
17.45 |
Vistagen Therapeutics Com New
|
0.1 |
$1.6M |
|
601k |
2.74 |
Inflarx Nv
(IFRX)
|
0.1 |
$1.6M |
|
631k |
2.59 |
Vascular Biogenics
|
0.1 |
$1.6M |
|
791k |
2.05 |
Cerevel Therapeutics Hldng I
(CERE)
|
0.1 |
$1.6M |
|
53k |
29.47 |
Avalo Therapeutics
|
0.1 |
$1.6M |
|
719k |
2.18 |
Cyclerion Therapeutics
|
0.1 |
$1.5M |
|
503k |
3.07 |
Pliant Therapeutics
(PLRX)
|
0.1 |
$1.5M |
|
87k |
16.88 |
Casi Pharmaceuticalsinc Com Stk
|
0.1 |
$1.5M |
|
1.2M |
1.19 |
Bellicum Pharmaceuticals Com New
|
0.1 |
$1.5M |
|
497k |
2.92 |
Vallon Pharmaceuticals
|
0.1 |
$1.4M |
|
198k |
7.27 |
Athira Pharma Call Option
(ATHA)
|
0.1 |
$1.4M |
|
150k |
9.38 |
Mustang Bio
|
0.1 |
$1.4M |
|
506k |
2.69 |
Ascendis Pharma A/s Sponsored Adr Call Option
(ASND)
|
0.1 |
$1.3M |
|
8.4k |
159.40 |
Reneo Pharmaceuticals
(RPHM)
|
0.1 |
$1.3M |
|
175k |
7.45 |
Black Diamond Therapeutics
(BDTX)
|
0.1 |
$1.3M |
|
151k |
8.45 |
Diamedica Therapeutics Com New
(DMAC)
|
0.1 |
$1.2M |
|
311k |
4.01 |
Solid Biosciences
|
0.1 |
$1.2M |
|
521k |
2.39 |
Quantum Si Com Cl A
(QSI)
|
0.1 |
$1.2M |
|
144k |
8.34 |
Applied Genetic Technol Corp C
|
0.1 |
$1.2M |
|
390k |
3.01 |
Anebulo Pharmaceuticals
(ANEB)
|
0.1 |
$1.2M |
|
172k |
6.73 |
Merus N V
(MRUS)
|
0.1 |
$1.1M |
|
51k |
22.00 |
Protagonist Therapeutics Call Option
(PTGX)
|
0.1 |
$1.1M |
|
61k |
17.73 |
Deciphera Pharmaceuticals Call Option
|
0.1 |
$1.0M |
|
30k |
33.96 |
Corbus Pharmaceuticals Hldgs
|
0.1 |
$968k |
|
949k |
1.02 |
Brainstorm Cell Therapeutics Com New
(BCLI)
|
0.1 |
$955k |
|
290k |
3.30 |
Harpoon Therapeutics
|
0.1 |
$879k |
|
111k |
7.90 |
Tempest Therapeutics
(TPST)
|
0.1 |
$851k |
|
59k |
14.47 |
Regulus Therapeutics Com New
|
0.1 |
$849k |
|
1.2M |
0.69 |
Hepion Pharmaceuticals
|
0.1 |
$847k |
|
553k |
1.53 |
Oncternal Therapeutics
|
0.1 |
$830k |
|
199k |
4.17 |
Tenax Therapeutics Com New
|
0.1 |
$826k |
|
466k |
1.77 |
Altamira Therapeutics SHS
|
0.1 |
$803k |
|
399k |
2.01 |
Astria Therapeutics
(ATXS)
|
0.1 |
$775k |
|
88k |
8.85 |
Aclaris Therapeutics
(ACRS)
|
0.1 |
$770k |
|
43k |
18.03 |
Assembly Biosciences
|
0.1 |
$747k |
|
215k |
3.48 |
Shattuck Labs
(STTK)
|
0.1 |
$739k |
|
36k |
20.39 |
Bcls Acquisition Corp Com Cl A
|
0.1 |
$739k |
|
74k |
10.02 |
Panbela Therapeutics
|
0.1 |
$734k |
|
338k |
2.17 |
Frazier Lifesciences Acqu Unit 12/09/2025
|
0.1 |
$725k |
|
73k |
9.92 |
Immunovant
(IMVT)
|
0.1 |
$722k |
|
83k |
8.69 |
Kiniksa Pharmaceuticals Com Cl A
|
0.0 |
$677k |
|
59k |
11.39 |
Passage Bio
(PASG)
|
0.0 |
$677k |
|
68k |
9.98 |
Stealth Biotherapeutics Corp Sponsored Ads
|
0.0 |
$651k |
|
479k |
1.36 |
Ocuphire Pharma
(OCUP)
|
0.0 |
$608k |
|
118k |
5.15 |
Apricus Biosciences
|
0.0 |
$589k |
|
244k |
2.41 |
Kaleido Biosciences Ord
(KLDO)
|
0.0 |
$546k |
|
100k |
5.46 |
Larimar Therapeutics
(LRMR)
|
0.0 |
$545k |
|
47k |
11.55 |
Relmada Therapeutics
(RLMD)
|
0.0 |
$544k |
|
21k |
26.23 |
Agenus Com New
|
0.0 |
$542k |
|
103k |
5.25 |
Cyclacel Pharmaceuticals
|
0.0 |
$524k |
|
99k |
5.27 |
Inmune Bio Ord
(INMB)
|
0.0 |
$517k |
|
27k |
19.41 |
Intercept Pharmaceuticals In
|
0.0 |
$513k |
|
35k |
14.84 |
Delcath Sys Com New
(DCTH)
|
0.0 |
$468k |
|
45k |
10.43 |
Immunoprecise Antibodies Com New
(IPA)
|
0.0 |
$459k |
|
74k |
6.21 |
Otonomy
|
0.0 |
$399k |
|
208k |
1.92 |
Eyepoint Pharmaceuticals Com New
(EYPT)
|
0.0 |
$380k |
|
36k |
10.43 |
Genocea Biosciences Com New
(GNCAQ)
|
0.0 |
$377k |
|
197k |
1.92 |
Puma Biotechnology
(PBYI)
|
0.0 |
$349k |
|
50k |
7.00 |
Orchard Therapeutics Ads
|
0.0 |
$341k |
|
148k |
2.30 |
Aadi Bioscience
(AADI)
|
0.0 |
$335k |
|
11k |
29.37 |
Mereo Biopharma Group Ads
(MREO)
|
0.0 |
$322k |
|
904k |
0.36 |
Aslan Pharmaceuticals Ads
|
0.0 |
$288k |
|
1.4M |
0.20 |
Cogent Biosciences
(COGT)
|
0.0 |
$258k |
|
31k |
8.40 |
Athenex
|
0.0 |
$228k |
|
76k |
2.99 |
Aptose Biosciences Com New
|
0.0 |
$224k |
|
102k |
2.19 |
Inventiva Sa Ads
(IVA)
|
0.0 |
$202k |
|
15k |
13.70 |
Gamida Cell SHS
|
0.0 |
$122k |
|
31k |
3.93 |
Soleno Therapeutics Com New
|
0.0 |
$112k |
|
122k |
0.92 |
Amryt Pharma Sponsored Ads
|
0.0 |
$81k |
|
34k |
2.37 |
Onconova Therapeutics Com New
(TRAW)
|
0.0 |
$57k |
|
15k |
3.78 |
Baudax Bio
|
0.0 |
$53k |
|
95k |
0.56 |