OrbiMed Advisors

Orbimed Advisors as of June 30, 2026

Portfolio Holdings for Orbimed Advisors

Orbimed Advisors holds 123 positions in its portfolio as reported in the June 2026 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Edgewise Therapeutics (EWTX) 11.7 $631M 16M 40.63
Enliven Therapeutics (ELVN) 6.4 $344M 6.8M 50.75
Eli Lilly & Co. (LLY) 5.7 $309M 258k 1199.43
Mbx Biosciences (MBX) 3.5 $189M 3.4M 55.20
Sinovac Biotech SHS 3.4 $185M 2.7M 67.85
Astrazeneca Ord (AZN) 3.2 $171M 916k 186.83
Structure Therapeutics Sponsored Ads (GPCR) 2.2 $119M 2.2M 53.67
Sionna Therapeutics (SION) 2.1 $112M 2.6M 43.99
Corvus Pharmaceuticals (CRVS) 2.0 $107M 7.2M 14.94
Arrivent Biopharma (AVBP) 1.9 $105M 3.0M 34.74
Abivax Sa Sponsored Ads Call Option (ABVX) 1.8 $100M 747k 133.26
Guardant Health (GH) 1.6 $88M 584k 150.03
Argenx Se Sponsored Adr (ARGX) 1.6 $86M 93k 927.77
Merck & Co (MRK) 1.6 $85M 663k 128.50
Uniqure Nv SHS (QURE) 1.5 $83M 1.8M 46.06
Praxis Precision Medicines I Com New (PRAX) 1.4 $77M 230k 334.79
Edwards Lifesciences (EW) 1.4 $76M 835k 90.46
Prelude Therapeutics (PRLD) 1.4 $73M 14M 5.33
Dyne Therapeutics (DYN) 1.3 $72M 3.2M 22.21
Natera (NTRA) 1.3 $71M 262k 271.45
UnitedHealth (UNH) 1.3 $71M 171k 415.63
Cg Oncology (CGON) 1.3 $69M 973k 71.05
Silverback Therapeutics (SPRY) 1.2 $66M 8.3M 8.01
Ascendis Pharma A/s Ord Shs (ASND) 1.2 $65M 245k 266.72
Humana (HUM) 1.2 $65M 164k 397.22
Cogent Biosciences (COGT) 1.2 $65M 1.7M 38.70
Boston Scientific Corporation (BSX) 1.2 $63M 1.5M 42.68
Intuitive Surgical Com New (ISRG) 1.2 $63M 158k 397.68
Mineralys Therapeutics (MLYS) 1.1 $57M 2.1M 26.98
Odyssey Therapeutics Common Stock 1.0 $56M 3.0M 18.71
Xenon Pharmaceuticals (XENE) 1.0 $54M 893k 60.36
Arcutis Biotherapeutics (ARQT) 1.0 $54M 2.0M 26.22
Bristol Myers Squibb (BMY) 1.0 $53M 925k 57.62
Q32 Bio (QTTB) 1.0 $53M 4.1M 12.74
Palvella Therapeutics Inc Ne Call Option (PVLA) 0.9 $51M 332k 152.82
Stryker Corporation (SYK) 0.9 $50M 159k 314.84
Caris Life Sciences (CAI) 0.9 $50M 2.8M 17.82
Anthem Call Option (ELV) 0.9 $48M 125k 386.73
Spdr Series Trust St Str Sp Biot Put Option (XBI) 0.9 $48M 300k 158.25
Thermo Fisher Scientific (TMO) 0.8 $46M 91k 501.36
Shattuck Labs (STTK) 0.8 $44M 6.3M 6.94
Upstream Bio (UPB) 0.7 $39M 5.7M 6.92
Crinetics Pharmaceuticals In (CRNX) 0.7 $37M 999k 37.42
Rhythm Pharmaceuticals (RYTM) 0.7 $36M 323k 111.03
Syndax Pharmaceuticals (SNDX) 0.6 $34M 1.5M 21.86
Forte Biosciences Com New (FBRX) 0.6 $34M 1.6M 21.25
Compass Therapeutics (CMPX) 0.6 $33M 15M 2.19
Nektar Therapeutics Com New (NKTR) 0.6 $33M 465k 69.81
Krystal Biotech (KRYS) 0.6 $31M 83k 371.67
Prelude Therapeutics Non Voting 0.6 $30M 5.7M 5.33
Axsome Therapeutics (AXSM) 0.5 $29M 118k 244.77
Kiniksa Pharmaceuticals Intl Ord Shs Cl A (KNSA) 0.5 $27M 421k 63.95
Trevi Therapeutics (TRVI) 0.5 $27M 1.4M 18.65
Disc Medicine (IRON) 0.5 $26M 358k 73.14
West Pharmaceutical Services (WST) 0.5 $25M 71k 359.00
Relmada Therapeutics (RLMD) 0.5 $25M 3.6M 6.92
Urogen Pharma (URGN) 0.5 $25M 676k 36.80
Sutro Biopharma Com Shs (STRO) 0.5 $25M 744k 33.20
Savara (SVRA) 0.5 $24M 4.0M 6.16
Neuropace (NPCE) 0.4 $24M 1.5M 15.89
Aura Biosciences (AURA) 0.4 $24M 3.3M 7.10
Protagonist Therapeutics (PTGX) 0.4 $24M 192k 122.58
Revolution Medicines Call Option (RVMD) 0.4 $23M 121k 187.28
Oric Pharmaceuticals (ORIC) 0.4 $22M 2.0M 10.83
Cybin Com New (HELP) 0.4 $22M 3.3M 6.61
BioCryst Pharmaceuticals (BCRX) 0.3 $19M 1.9M 10.00
Bioage Labs (BIOA) 0.3 $18M 752k 24.51
Lexeo Therapeutics (LXEO) 0.3 $18M 3.9M 4.66
Aadi Bioscience (WHWK) 0.3 $18M 3.9M 4.58
Definium Therapeutics Com Shs (DFTX) 0.3 $17M 365k 47.04
Spyre Therapeutics Com New (SYRE) 0.3 $17M 186k 88.78
Corbus Pharmaceuticals Hldgs Com New (CRBP) 0.3 $16M 1.7M 9.38
Vera Therapeutics Cl A (VERA) 0.3 $16M 370k 42.91
Alumis (ALMS) 0.3 $15M 548k 28.14
Eyepoint Com New (EYPT) 0.3 $15M 1.1M 14.30
Waters Corporation (WAT) 0.3 $15M 40k 375.04
Monopar Therapeutics Com New (MNPR) 0.3 $15M 157k 92.59
Travere Therapeutics (TVTX) 0.3 $14M 253k 56.81
Taysha Gene Therapies Com Shs (TSHA) 0.3 $14M 2.0M 6.81
Biogen Idec (BIIB) 0.2 $13M 62k 216.06
Dianthus Therapeutics (DNTH) 0.2 $11M 115k 97.48
Spruce Biosciences Com New (SPRB) 0.2 $11M 200k 54.00
Lifestance Health Group (LFST) 0.2 $10M 947k 10.71
Erasca (ERAS) 0.2 $9.1M 496k 18.32
Protara Therapeutics Com Stk (TARA) 0.2 $8.5M 2.2M 3.82
Keros Therapeutics (KROS) 0.2 $8.1M 759k 10.70
Janux Therapeutics (JANX) 0.1 $8.1M 525k 15.36
Tectonic Therapeutic (TECX) 0.1 $7.8M 227k 34.38
Adicet Bio Com New (ACET) 0.1 $7.3M 845k 8.64
Pharvaris N V (PHVS) 0.1 $7.1M 205k 34.58
Alto Neuroscience Com Shs (ANRO) 0.1 $6.8M 258k 26.39
Zentalis Pharmaceuticals (ZNTL) 0.1 $6.7M 1.4M 4.85
Bright Minds Biosciences Com New (DRUG) 0.1 $6.5M 93k 70.20
Alx Oncology Hldgs (ALXO) 0.1 $5.9M 2.9M 2.07
Travere Therapeutics Note 0.500% 5/1 (Principal) 0.1 $5.9M 5.0M 1.18
Xilio Therapeutics (XLO) 0.1 $5.7M 592k 9.58
Bicara Therapeutics (BCAX) 0.1 $5.7M 191k 29.69
Imagenebio (IMA) 0.1 $5.4M 909k 5.90
Alnylam Pharmaceuticals (ALNY) 0.1 $5.1M 17k 301.03
Palisade Bio (PALI) 0.1 $4.9M 2.3M 2.09
Revolution Medicines Note 0.500% 5/0 (Principal) 0.1 $4.4M 3.5M 1.25
Ataibeckley Com Shs (ATAI) 0.1 $4.2M 798k 5.27
Ptc Therapeutics I (PTCT) 0.1 $4.0M 49k 81.57
CryoLife (AORT) 0.1 $3.9M 175k 22.47
Neumora Therapeutics (NMRA) 0.1 $3.6M 2.1M 1.70
ACADIA Pharmaceuticals (ACAD) 0.1 $3.5M 137k 25.30
Amylyx Pharmaceuticals (AMLX) 0.1 $3.3M 183k 17.96
Tyra Biosciences (TYRA) 0.1 $3.3M 102k 31.94
Rapport Therapeutics (RAPP) 0.1 $3.2M 77k 41.67
Agomab Therapeutics Nv Sponsored Ads (AGMB) 0.0 $2.5M 193k 12.98
Tarsus Pharmaceuticals (TARS) 0.0 $2.2M 36k 62.94
Aclaris Therapeutics (ACRS) 0.0 $2.2M 422k 5.29
Cytokinetics Com New (CYTK) 0.0 $2.2M 26k 85.19
Inspiremd (NSPR) 0.0 $2.2M 3.1M 0.70
Ocular Therapeutix (OCUL) 0.0 $2.2M 220k 9.82
Evommune Com Shs (EVMN) 0.0 $2.1M 161k 13.29
Belite Bio Sponsored Ads (BLTE) 0.0 $2.0M 13k 153.99
Ovid Therapeutics (OVID) 0.0 $2.0M 747k 2.69
Eupraxia Pharmaceuticals (EPRX) 0.0 $1.8M 269k 6.61
Sellas Life Sciences Group I Com New Put Option (SLS) 0.0 $1.4M 93k 14.76
Cogent Biosciences Note 1.625%11/1 (Principal) 0.0 $1.2M 1.0M 1.23
Viridian Therapeutics Note 1.750% 5/1 (Principal) 0.0 $1.1M 1.0M 1.07
Traws Pharma Com New (TRAW) 0.0 $1.0M 1.2M 0.84