Perceptive Advisors as of Sept. 30, 2025
Portfolio Holdings for Perceptive Advisors
Perceptive Advisors holds 92 positions in its portfolio as reported in the September 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Rhythm Pharmaceuticals (RYTM) | 93.0 | $42B | 419M | 100.99 | |
| Ascendis Pharma A/s Sponsored Adr (ASND) | 0.5 | $216M | 1.1M | 198.81 | |
| Arcellx Common Stock (ACLX) | 0.4 | $203M | 2.5M | 82.10 | |
| Celcuity (CELC) | 0.3 | $146M | 3.0M | 49.40 | |
| Nuvalent Inc-a (NUVL) | 0.3 | $135M | 1.6M | 86.48 | |
| Merus N V (MRUS) | 0.3 | $127M | 1.4M | 94.15 | |
| Amylyx Pharmaceuticals (AMLX) | 0.3 | $122M | 9.0M | 13.59 | |
| Roivant Sciences SHS (ROIV) | 0.2 | $112M | 7.4M | 15.13 | |
| Meiragtx Holdings (MGTX) | 0.2 | $104M | 13M | 8.22 | |
| Insmed Com Par $.01 (INSM) | 0.2 | $101M | 702k | 144.01 | |
| Travere Therapeutics (TVTX) | 0.2 | $91M | 3.8M | 23.90 | |
| CryoLife (AORT) | 0.2 | $86M | 2.0M | 42.34 | |
| Praxis Precision Medicines I Com New (PRAX) | 0.2 | $83M | 1.6M | 53.00 | |
| Immatics SHS (IMTX) | 0.2 | $80M | 9.4M | 8.52 | |
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 0.2 | $75M | 3.1M | 24.25 | |
| Solid Biosciences Com New (SLDB) | 0.2 | $73M | 12M | 6.17 | |
| Protagonist Therapeutics (PTGX) | 0.2 | $68M | 1.0M | 66.43 | |
| Neurocrine Biosciences (NBIX) | 0.1 | $63M | 450k | 140.38 | |
| Edgewise Therapeutics (EWTX) | 0.1 | $62M | 3.8M | 16.22 | |
| Verona Pharma Sponsored Ads (VRNA) | 0.1 | $56M | 524k | 106.71 | |
| Penumbra (PEN) | 0.1 | $56M | 221k | 253.32 | |
| Akero Therapeutics (AKRO) | 0.1 | $54M | 1.1M | 47.48 | |
| Apogee Therapeutics (APGE) | 0.1 | $54M | 1.4M | 39.73 | |
| Omada Health (OMDA) | 0.1 | $53M | 2.4M | 22.11 | |
| Amicus Therapeutics (FOLD) | 0.1 | $50M | 6.4M | 7.88 | |
| Astria Therapeutics (ATXS) | 0.1 | $47M | 6.5M | 7.28 | |
| Inhibrx Biosciences (INBX) | 0.1 | $45M | 1.3M | 33.68 | |
| Repligen Corporation (RGEN) | 0.1 | $36M | 270k | 133.67 | |
| Zymeworks Del (ZYME) | 0.1 | $36M | 2.1M | 17.08 | |
| Sionna Therapeutics (SION) | 0.1 | $35M | 1.2M | 29.41 | |
| Caris Life Sciences (CAI) | 0.1 | $33M | 1.1M | 30.25 | |
| Abivax Sa Sponsored Ads (ABVX) | 0.1 | $33M | 389k | 84.90 | |
| Miragen Therapeutics (VRDN) | 0.1 | $32M | 1.5M | 21.58 | |
| Cytomx Therapeutics (CTMX) | 0.1 | $31M | 9.7M | 3.19 | |
| Boston Scientific Corporation (BSX) | 0.1 | $30M | 310k | 97.63 | |
| Aldeyra Therapeutics (ALDX) | 0.1 | $27M | 5.2M | 5.22 | |
| Bright Minds Biosciences Com New (DRUG) | 0.1 | $27M | 449k | 60.66 | |
| Immunovant (IMVT) | 0.1 | $26M | 1.6M | 16.12 | |
| EXACT Sciences Corporation (EXAS) | 0.1 | $26M | 466k | 54.71 | |
| Palvella Therapeutics Inc Ne (PVLA) | 0.1 | $25M | 395k | 62.69 | |
| Oruka Therapeutics (ORKA) | 0.1 | $24M | 1.3M | 19.23 | |
| Intuitive Surgical Com New (ISRG) | 0.1 | $23M | 52k | 447.23 | |
| Irhythm Technologies (IRTC) | 0.0 | $21M | 123k | 171.99 | |
| Aquestive Therapeutics (AQST) | 0.0 | $21M | 3.8M | 5.59 | |
| Spyre Therapeutics Com New (SYRE) | 0.0 | $21M | 1.2M | 16.76 | |
| Adagio Med Hldgs (ADGM) | 0.0 | $19M | 9.9M | 1.94 | |
| Axsome Therapeutics (AXSM) | 0.0 | $18M | 149k | 121.45 | |
| Adma Biologics (ADMA) | 0.0 | $17M | 1.2M | 14.66 | |
| Engene Holdings (ENGN) | 0.0 | $14M | 2.1M | 6.83 | |
| Health Sciences Acq Corp 2 (OBIO) | 0.0 | $13M | 5.3M | 2.48 | |
| Nurix Therapeutics (NRIX) | 0.0 | $13M | 1.4M | 9.24 | |
| Rapport Therapeutics (RAPP) | 0.0 | $12M | 404k | 29.70 | |
| Outset Med Com New (OM) | 0.0 | $12M | 833k | 14.12 | |
| Nautilus Biotechnology (NAUT) | 0.0 | $11M | 13M | 0.84 | |
| Corvus Pharmaceuticals (CRVS) | 0.0 | $11M | 1.4M | 7.37 | |
| Kodiak Sciences (KOD) | 0.0 | $10M | 635k | 16.37 | |
| Septerna (SEPN) | 0.0 | $10M | 542k | 18.81 | |
| Gossamer Bio (GOSS) | 0.0 | $10M | 3.8M | 2.63 | |
| Kymera Therapeutics (KYMR) | 0.0 | $9.6M | 170k | 56.60 | |
| Inhibikase Therapeutics Com New (IKT) | 0.0 | $8.8M | 5.4M | 1.62 | |
| Celcuity Note 2.750% 8/0 (Principal) | 0.0 | $8.7M | 6.5M | 1.34 | |
| Contineum Therapeutics Cl A (CTNM) | 0.0 | $8.4M | 715k | 11.75 | |
| Xenon Pharmaceuticals (XENE) | 0.0 | $8.1M | 201k | 40.15 | |
| Anteris Technologies Global (AVR) | 0.0 | $7.7M | 1.7M | 4.50 | |
| Janux Therapeutics (JANX) | 0.0 | $7.2M | 293k | 24.44 | |
| Ocuphire Pharma (IRD) | 0.0 | $7.1M | 4.3M | 1.65 | |
| Tempus Ai Cl A (TEM) | 0.0 | $6.9M | 85k | 80.71 | |
| Dyne Therapeutics (DYN) | 0.0 | $6.8M | 540k | 12.65 | |
| Krystal Biotech (KRYS) | 0.0 | $6.2M | 35k | 176.53 | |
| Beta Bionics (BBNX) | 0.0 | $5.5M | 278k | 19.87 | |
| Crescent Biopharma (CBIO) | 0.0 | $5.4M | 454k | 11.89 | |
| Heartflow Inc/Sh | 0.0 | $5.0M | 150k | 33.66 | |
| Rapt Therapeutics Com New (RAPT) | 0.0 | $4.7M | 184k | 25.79 | |
| Pepgen (PEPG) | 0.0 | $3.8M | 830k | 4.62 | |
| Belite Bio Sponsored Ads (BLTE) | 0.0 | $3.7M | 50k | 74.00 | |
| Scpharmaceuticals (SCPH) | 0.0 | $3.3M | 583k | 5.67 | |
| Viking Therapeutics (VKTX) | 0.0 | $2.8M | 106k | 26.28 | |
| Pyxis Oncology Common Stock (PYXS) | 0.0 | $2.6M | 1.2M | 2.22 | |
| Athira Pharma | 0.0 | $2.2M | 540k | 4.14 | |
| Silverback Therapeutics Put Option (SPRY) | 0.0 | $2.0M | 200k | 10.05 | |
| Trinity Biotech Spons Adr New (TRIB) | 0.0 | $1.9M | 1.8M | 1.04 | |
| Avalo Therapeutics Com New (AVTX) | 0.0 | $1.8M | 140k | 12.71 | |
| Envveno Medical (NVNO) | 0.0 | $1.6M | 1.8M | 0.91 | |
| Lyra Therapeutics Com New (LYRA) | 0.0 | $1.5M | 229k | 6.53 | |
| Uniqure Nv SHS (QURE) | 0.0 | $1.2M | 20k | 58.37 | |
| Lexeo Therapeutics (LXEO) | 0.0 | $929k | 140k | 6.64 | |
| Biodesix | 0.0 | $821k | 109k | 7.55 | |
| Alto Neuroscience Com Shs (ANRO) | 0.0 | $625k | 155k | 4.02 | |
| Apyx Medical Corporation (APYX) | 0.0 | $321k | 150k | 2.14 | |
| Ensysce Biosciences Com New (ENSC) | 0.0 | $205k | 87k | 2.37 | |
| Revolution Medicines *w Exp 12/17/202 (RVMDW) | 0.0 | $75k | 250k | 0.30 | |
| Surrozen *w Exp 08/01/203 (SRZNW) | 0.0 | $3.0k | 167k | 0.02 |
