Sio Capital Management

Sio Capital Management as of Dec. 31, 2025

Portfolio Holdings for Sio Capital Management

Sio Capital Management holds 68 positions in its portfolio as reported in the December 2025 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Celcuity (CELC) 7.5 $48M 477k 99.74
Cigna Corp (CI) 7.5 $47M 172k 275.23
Sanofi Sa Sponsored Adr (SNY) 7.4 $47M 972k 48.46
Maximus (MMS) 6.8 $43M 500k 86.32
Zimmer Holdings (ZBH) 5.5 $35M 386k 89.92
Rhythm Pharmaceuticals Put Option (RYTM) 4.5 $28M 266k 107.04
Kenvue (KVUE) 4.0 $25M 1.5M 17.25
Organon & Co Common Stock (OGN) 3.9 $25M 3.4M 7.17
Icon SHS (ICLR) 3.6 $23M 127k 182.22
Waystar Holding Corp (WAY) 3.2 $20M 614k 32.75
Livanova SHS (LIVN) 3.1 $20M 322k 61.53
Dianthus Therapeutics (DNTH) 3.1 $20M 475k 41.21
Biohaven (BHVN) 2.2 $14M 1.2M 11.29
Structure Therapeutics Sponsored Ads (GPCR) 2.2 $14M 202k 69.55
BioMarin Pharmaceutical (BMRN) 2.2 $14M 233k 59.43
Tyra Biosciences (TYRA) 2.2 $14M 526k 26.29
Brightspring Health Svcs (BTSG) 1.8 $12M 308k 37.45
Centene Corporation (CNC) 1.8 $11M 274k 41.15
Charles River Laboratories (CRL) 1.7 $11M 55k 199.48
Teleflex Incorporated (TFX) 1.7 $11M 87k 122.04
Anteris Technologies Global (AVR) 1.5 $9.4M 1.9M 4.99
Protara Therapeutics Com Stk (TARA) 1.4 $9.1M 1.7M 5.33
Cross Country Healthcare (CCRN) 1.4 $8.7M 1.1M 8.10
Haemonetics Corporation (HAE) 1.2 $7.4M 93k 80.15
Biosante Pharmaceuticals (ANIP) 1.1 $6.9M 87k 78.94
Aquestive Therapeutics (AQST) 1.0 $6.4M 993k 6.46
Bright Minds Biosciences Com New (DRUG) 1.0 $6.4M 82k 78.04
Edgewise Therapeutics (EWTX) 0.9 $5.9M 238k 24.82
Abivax Sa Sponsored Ads (ABVX) 0.9 $5.8M 43k 134.85
Crinetics Pharmaceuticals In (CRNX) 0.9 $5.8M 125k 46.55
Rapport Therapeutics (RAPP) 0.9 $5.6M 185k 30.34
AmerisourceBergen (COR) 0.8 $5.4M 16k 337.75
McKesson Corporation (MCK) 0.8 $5.2M 6.4k 820.29
Disc Medicine (IRON) 0.7 $4.6M 58k 79.41
Proqr Therapeutics N V Shs Euro (PRQR) 0.7 $4.4M 2.2M 2.02
Fulcrum Therapeutics (FULC) 0.7 $4.3M 382k 11.31
Savara (SVRA) 0.6 $3.7M 614k 6.03
Oruka Therapeutics (ORKA) 0.6 $3.6M 118k 30.31
Ventyx Biosciences (VTYX) 0.6 $3.5M 388k 9.03
Pmv Pharmaceuticals (PMVP) 0.5 $3.3M 2.6M 1.25
Shoulder Innovations Common Stock (SI) 0.5 $3.3M 228k 14.30
Aligos Therapeutics Com New (ALGS) 0.5 $3.1M 336k 9.32
Vir Biotechnology (VIR) 0.5 $2.9M 478k 6.03
Alkermes SHS (ALKS) 0.4 $2.7M 95k 27.98
Ideaya Biosciences (IDYA) 0.4 $2.6M 76k 34.57
Kymera Therapeutics (KYMR) 0.4 $2.5M 32k 77.81
Elicio Therapeutics Put Option (ELTX) 0.4 $2.4M 297k 7.96
Ovid Therapeutics (OVID) 0.4 $2.3M 1.4M 1.63
Context Therapeutics (CNTX) 0.3 $2.0M 1.3M 1.47
Hyperfine Com Cl A (HYPR) 0.3 $2.0M 2.0M 0.98
Outlook Therapeutics Put Option (OTLK) 0.3 $1.8M 1.1M 1.58
Bridgebio Oncology Therapeut Com New (BBOT) 0.3 $1.6M 131k 12.52
Ibio Com New (IBIO) 0.2 $1.4M 740k 1.93
Xilio Therapeutics (XLO) 0.2 $1.4M 2.1M 0.64
Adagio Med Hldgs (ADGM) 0.2 $1.3M 1.3M 1.04
Avalo Therapeutics Com New (AVTX) 0.2 $1.3M 72k 18.16
Neuroone Med Technologies Com New (NMTC) 0.1 $864k 1.1M 0.76
Tela Bio (TELA) 0.1 $751k 636k 1.18
Foghorn Therapeutics (FHTX) 0.1 $664k 123k 5.40
Senseonics Hldgs (SENS) 0.1 $639k 116k 5.52
Enanta Pharmaceuticals (ENTA) 0.1 $631k 40k 15.77
Terns Pharmaceuticals (TERN) 0.1 $408k 10k 40.40
Modular Med Com New (MODD) 0.0 $286k 786k 0.36
Nyxoah S A SHS (NYXH) 0.0 $234k 51k 4.60
Boundless Bio (BOLD) 0.0 $196k 164k 1.20
Nextcure Com New (NXTC) 0.0 $155k 11k 14.19
Rocket Pharmaceuticals *w Exp 09/02/202 (RCKTW) 0.0 $7.2k 400k 0.02
Humacyte *w Exp 08/27/202 (HUMAW) 0.0 $4.9k 50k 0.10