Sio Capital Management
Latest statistics and disclosures from Sio Capital Management's latest quarterly 13F-HR filing:
- Top 5 stock holdings are MMS, WAY, ICLR, COR, DNTH, and represent 26.61% of Sio Capital Management's stock portfolio.
- Added to shares of these 10 stocks: CORT (+$27M), COR (+$27M), WAY (+$25M), GSK (+$21M), ICLR (+$20M), AVR (+$20M), ABT (+$19M), MMS (+$17M), EMBC (+$16M), ANIP (+$14M).
- Started 23 new stock positions in ABT, ZBIO, RLMD, CORT, CMPS, IART, XLO, OSCR, SER, SION. OCUL, GSK, ERAS, OKUR, EMBC, REPL, QDEL, MNPR, MODD, SLP, IMNM, ANTX, EYPT.
- Reduced shares in these 10 stocks: CI (-$47M), SNY (-$35M), CELC (-$32M), ZBH (-$29M), RYTM (-$28M), KVUE (-$25M), OGN (-$15M), BTSG (-$12M), CRL (-$11M), DNTH (-$8.8M).
- Sold out of its positions in AVTX, BTSG, CI, CRL, FULC, IDYA, KVUE, MCK, Modular Med, NXTC. OTLK, RYTM, VTYX, Xilio Therapeutics, ALKS.
- Sio Capital Management was a net buyer of stock by $68M.
- Sio Capital Management has $697M in assets under management (AUM), dropping by 9.68%.
- Central Index Key (CIK): 0001482416
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Portfolio Holdings for Sio Capital Management
Sio Capital Management holds 76 positions in its portfolio as reported in the March 2026 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Maximus (MMS) | 7.1 | $49M | +53% | 769k | 64.10 |
|
| Waystar Holding Corp (WAY) | 5.7 | $40M | +167% | 1.6M | 24.11 |
|
| Icon SHS (ICLR) | 4.9 | $34M | +140% | 306k | 110.66 |
|
| AmerisourceBergen (COR) | 4.5 | $32M | +534% | 101k | 314.14 |
|
| Dianthus Therapeutics (DNTH) | 4.5 | $31M | -22% | 370k | 83.92 |
|
| Anteris Technologies Global (AVR) | 4.3 | $30M | +187% | 5.4M | 5.55 |
|
| Corcept Therapeutics Incorporated (CORT) | 3.9 | $27M | NEW | 675k | 40.31 |
|
| Livanova SHS (LIVN) | 3.8 | $27M | +30% | 422k | 63.56 |
|
| Tyra Biosciences (TYRA) | 3.3 | $23M | +15% | 605k | 38.30 |
|
| Celcuity (CELC) | 3.2 | $22M | -59% | 194k | 114.14 |
|
| GSK Sponsored Adr (GSK) | 3.1 | $21M | NEW | 386k | 55.19 |
|
| Biosante Pharmaceuticals (ANIP) | 2.9 | $20M | +204% | 266k | 76.90 |
|
| Abbott Laboratories (ABT) | 2.7 | $19M | NEW | 187k | 102.67 |
|
| Embecta Corp Common Stock (EMBC) | 2.3 | $16M | NEW | 1.8M | 8.84 |
|
| Abivax Sa Sponsored Ads (ABVX) | 2.2 | $15M | +214% | 136k | 111.35 |
|
| Vir Biotechnology (VIR) | 1.9 | $13M | +213% | 1.5M | 8.96 |
|
| Haemonetics Corporation (HAE) | 1.8 | $12M | +138% | 221k | 56.36 |
|
| Sionna Therapeutics (SION) | 1.7 | $12M | NEW | 294k | 40.09 |
|
| Sanofi Sa Sponsored Adr (SNY) | 1.7 | $12M | -75% | 240k | 48.18 |
|
| Rapport Therapeutics (RAPP) | 1.6 | $12M | +97% | 367k | 31.29 |
|
| Teleflex Incorporated (TFX) | 1.6 | $11M | +9% | 95k | 119.61 |
|
| BioMarin Pharmaceutical (BMRN) | 1.6 | $11M | -16% | 194k | 56.49 |
|
| Cross Country Healthcare (CCRN) | 1.5 | $10M | +2% | 1.1M | 9.40 |
|
| Protara Therapeutics Com Stk (TARA) | 1.5 | $10M | +14% | 2.0M | 5.21 |
|
| Structure Therapeutics Sponsored Ads (GPCR) | 1.4 | $10M | +3% | 209k | 48.20 |
|
| Biohaven (BHVN) | 1.4 | $9.8M | -6% | 1.2M | 8.46 |
|
| Monopar Therapeutics Com New (MNPR) | 1.4 | $9.5M | NEW | 174k | 54.79 |
|
| Eyepoint Com New (EYPT) | 1.3 | $9.3M | NEW | 722k | 12.89 |
|
| Crinetics Pharmaceuticals In (CRNX) | 1.3 | $9.1M | +100% | 250k | 36.32 |
|
| Edgewise Therapeutics (EWTX) | 1.2 | $8.5M | +13% | 269k | 31.50 |
|
| Compass Pathways Sponsored Ads (CMPS) | 1.2 | $8.3M | NEW | 1.5M | 5.53 |
|
| Ocular Therapeutix (OCUL) | 1.2 | $8.2M | NEW | 969k | 8.47 |
|
| Aquestive Therapeutics (AQST) | 1.1 | $8.0M | +93% | 1.9M | 4.15 |
|
| Relmada Therapeutics (RLMD) | 1.0 | $6.7M | NEW | 965k | 6.96 |
|
| Oruka Therapeutics (ORKA) | 0.9 | $6.5M | +12% | 133k | 49.05 |
|
| Zenas Biopharma (ZBIO) | 0.9 | $6.5M | NEW | 332k | 19.55 |
|
| Bright Minds Biosciences Com New (DRUG) | 0.9 | $6.3M | +5% | 86k | 72.97 |
|
| Quidel Corp (QDEL) | 0.8 | $5.9M | NEW | 359k | 16.43 |
|
| Zimmer Holdings (ZBH) | 0.8 | $5.7M | -83% | 63k | 90.42 |
|
| Replimune Group (REPL) | 0.8 | $5.5M | NEW | 720k | 7.65 |
|
| Organon & Co Common Stock (OGN) | 0.7 | $5.2M | -74% | 866k | 5.99 |
|
| Onkure Therapeutics Com Cl A (OKUR) | 0.6 | $4.5M | NEW | 1.1M | 4.14 |
|
| Disc Medicine (IRON) | 0.6 | $4.2M | +13% | 65k | 63.94 |
|
| Pmv Pharmaceuticals (PMVP) | 0.5 | $3.8M | +16% | 3.1M | 1.24 |
|
| Immunome (IMNM) | 0.5 | $3.6M | NEW | 165k | 21.87 |
|
| Integra Lifesciences Hldgs C Com New (IART) | 0.5 | $3.6M | NEW | 383k | 9.42 |
|
| Savara (SVRA) | 0.5 | $3.4M | 614k | 5.46 |
|
|
| Centene Corporation Put Option (CNC) | 0.5 | $3.3M | -63% | 100k | 32.74 |
|
| Proqr Therapeutics N V Shs Euro (PRQR) | 0.5 | $3.2M | -9% | 2.0M | 1.62 |
|
| Shoulder Innovations Common Stock (SI) | 0.4 | $3.1M | -7% | 211k | 14.53 |
|
| Ovid Therapeutics (OVID) | 0.4 | $2.8M | -12% | 1.3M | 2.22 |
|
| Kymera Therapeutics (KYMR) | 0.4 | $2.7M | 32k | 83.29 |
|
|
| Aligos Therapeutics Com New (ALGS) | 0.3 | $2.4M | -2% | 327k | 7.43 |
|
| Context Therapeutics (CNTX) | 0.3 | $2.4M | -31% | 918k | 2.62 |
|
| An2 Therapeutics (ANTX) | 0.3 | $2.2M | NEW | 657k | 3.42 |
|
| Serina Therapeutics Com Shs (SER) | 0.3 | $1.9M | NEW | 1.0M | 1.94 |
|
| Ibio Com New (IBIO) | 0.2 | $1.7M | +22% | 904k | 1.90 |
|
| Adagio Med Hldgs (ADGM) | 0.2 | $1.5M | 1.3M | 1.15 |
|
|
| Xilio Therapeutics (XLO) | 0.2 | $1.3M | NEW | 153k | 8.41 |
|
| Bridgebio Oncology Therapeut Com New (BBOT) | 0.2 | $1.2M | 131k | 8.95 |
|
|
| Hyperfine Com Cl A (HYPR) | 0.2 | $1.1M | -50% | 1.0M | 1.08 |
|
| Senseonics Hldgs (SENS) | 0.1 | $771k | 116k | 6.66 |
|
|
| Foghorn Therapeutics (FHTX) | 0.1 | $587k | 123k | 4.78 |
|
|
| Terns Pharmaceuticals (TERN) | 0.1 | $533k | 10k | 52.72 |
|
|
| Enanta Pharmaceuticals (ENTA) | 0.1 | $505k | 40k | 12.63 |
|
|
| Tela Bio (TELA) | 0.1 | $395k | 636k | 0.62 |
|
|
| Neuroone Med Technologies Com New | 0.1 | $386k | -56% | 497k | 0.78 |
|
| Boundless Bio (BOLD) | 0.0 | $180k | 164k | 1.10 |
|
|
| Nyxoah S A SHS (NYXH) | 0.0 | $148k | 51k | 2.92 |
|
|
| Modular Med Com New (MODD) | 0.0 | $138k | NEW | 26k | 5.28 |
|
| Elicio Therapeutics Put Option (ELTX) | 0.0 | $125k | -96% | 12k | 10.69 |
|
| Erasca (ERAS) | 0.0 | $81k | NEW | 5.0k | 16.18 |
|
| Oscar Health Cl A Put Option (OSCR) | 0.0 | $34k | NEW | 3.0k | 11.47 |
|
| Rocket Pharmaceuticals *w Exp 09/02/202 (RCKTW) | 0.0 | $7.0k | 400k | 0.02 |
|
|
| Humacyte *w Exp 08/27/202 (HUMAW) | 0.0 | $4.6k | 50k | 0.09 |
|
|
| Simulations Plus (SLP) | 0.0 | $2.4k | NEW | 200.00 | 11.82 |
|
Past Filings by Sio Capital Management
SEC 13F filings are viewable for Sio Capital Management going back to 2010
- Sio Capital Management 2026 Q1 filed May 14, 2026
- Sio Capital Management 2025 Q4 filed Feb. 17, 2026
- Sio Capital Management 2025 Q3 filed Nov. 13, 2025
- Sio Capital Management 2025 Q2 filed Aug. 13, 2025
- Sio Capital Management 2025 Q1 filed May 15, 2025
- Sio Capital Management 2024 Q4 filed Feb. 14, 2025
- Sio Capital Management 2024 Q3 filed Nov. 14, 2024
- Sio Capital Management 2024 Q2 filed Aug. 14, 2024
- Sio Capital Management 2024 Q1 filed May 15, 2024
- Sio Capital Management 2023 Q3 filed Nov. 14, 2023
- Sio Capital Management 2023 Q2 filed Aug. 14, 2023
- Sio Capital Management 2023 Q1 filed May 12, 2023
- Sio Capital Management 2022 Q4 filed Feb. 13, 2023
- Sio Capital Management 2022 Q3 filed Nov. 14, 2022
- Sio Capital Management 2022 Q2 filed Aug. 15, 2022
- Sio Capital Management 2022 Q1 filed May 16, 2022