Sphera Funds Management

Sphera Funds Management as of March 31, 2015

Portfolio Holdings for Sphera Funds Management

Sphera Funds Management holds 147 positions in its portfolio as reported in the March 2015 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Ishares Tr Index option 10.4 $100M 8.0k 12437.00
Spdr S&p 500 Etf Tr option 7.5 $72M 3.5k 20643.14
Actavis 6.0 $57M 192k 297.62
Pfizer (PFE) 3.7 $36M 1.0M 34.79
Spdr S&p Oil & Gas Exp & Pr put 3.4 $33M 1.5k 22042.00
Gilead Sciences (GILD) 3.3 $31M 320k 98.13
Teva Pharmaceutical Industries (TEVA) 2.6 $25M 403k 62.30
Abbvie (ABBV) 2.5 $24M 407k 58.54
Teva Pharmaceutical Inds Ltd option 2.3 $22M 3.5k 6230.00
Merck & Co (MRK) 2.2 $22M 375k 57.48
Amgen (AMGN) 2.0 $19M 120k 159.85
Endo International 2.0 $19M 210k 89.70
Mylan Nv 1.7 $16M 272k 59.35
Auspex Pharmaceuticals 1.3 $13M 125k 100.27
Ormat Technologies (ORA) 1.2 $12M 80k 150.50
AMAG Pharmaceuticals 1.1 $11M 200k 54.66
Ishares Tr Index option 1.1 $10M 300.00 34343.33
BioMarin Pharmaceutical (BMRN) 1.0 $10M 80k 124.62
Novartis (NVS) 1.0 $9.9M 100k 98.61
Select Sector Spdr Tr option 1.0 $9.4M 1.3k 7250.00
Valeant Pharmaceuticals Int 0.9 $9.1M 46k 198.62
United Therapeutics Corporation (UTHR) 0.9 $8.4M 49k 172.44
Clovis Oncology 0.9 $8.3M 113k 74.23
Celgene Corporation 0.8 $8.1M 70k 115.29
Verint Systems (VRNT) 0.8 $7.6M 122k 61.93
Shire 0.8 $7.2M 135k 53.65
Seattle Genetics 0.7 $7.1M 200k 35.35
iShares Russell 2000 Index (IWM) 0.7 $7.0M 56k 124.37
Array BioPharma 0.7 $6.8M 924k 7.37
Bristol Myers Squibb (BMY) 0.7 $6.5M 100k 64.50
Dyax 0.6 $6.2M 368k 16.75
AstraZeneca (AZN) 0.6 $5.9M 87k 68.43
CHECK POINT SOFTWARE Technolog Com Stk (CHKP) 0.6 $5.9M 72k 81.97
Insys Therapeutics 0.6 $5.8M 100k 58.13
Concert Pharmaceuticals I equity 0.6 $5.7M 375k 15.14
Bellicum Pharma 0.6 $5.7M 250k 22.81
Apple (AAPL) 0.6 $5.3M 43k 124.42
Tekmira Pharmaceuticals Corporation 0.5 $5.2M 299k 17.46
Insmed (INSM) 0.5 $5.2M 250k 20.80
Kamada Ord Ils1.00 (KMDA) 0.5 $5.2M 294k 17.59
Vanda Pharmaceuticals (VNDA) 0.5 $5.1M 543k 9.30
Towers Watson & Co 0.5 $5.1M 38k 132.19
Forward Pharma A/s 0.5 $5.1M 180k 28.32
Amicus Therapeutics (FOLD) 0.5 $4.9M 450k 10.88
Relypsa 0.5 $4.9M 135k 36.07
Catalyst Pharmaceutical Partners (CPRX) 0.5 $4.8M 1.1M 4.33
Impax Laboratories 0.5 $4.7M 100k 46.87
Medivation 0.5 $4.7M 36k 129.06
Applied Genetic Technol Corp C 0.5 $4.7M 235k 19.99
DepoMed 0.5 $4.5M 200k 22.41
Kythera Biopharmaceuticals I 0.5 $4.5M 90k 50.16
Health Care SPDR (XLV) 0.5 $4.3M 60k 72.49
CVS Caremark Corporation (CVS) 0.5 $4.4M 42k 103.22
Broadcom Corporation 0.5 $4.4M 101k 43.29
Alexion Pharmaceuticals 0.5 $4.3M 25k 173.32
Alder Biopharmaceuticals 0.5 $4.3M 150k 28.86
Biogen Idec (BIIB) 0.4 $4.2M 10k 422.20
Intercept Pharmaceuticals In 0.4 $4.2M 15k 282.00
Ptc Therapeutics I (PTCT) 0.4 $4.3M 70k 60.86
Starbucks Corporation (SBUX) 0.4 $4.1M 87k 47.35
A. O. Smith Corporation (AOS) 0.4 $4.0M 62k 65.67
Portola Pharmaceuticals 0.4 $3.8M 100k 37.96
Kite Pharma 0.4 $3.8M 66k 57.68
Ariad Pharmaceuticals 0.4 $3.7M 445k 8.24
Spdr Euro Stoxx 50 Etf (FEZ) 0.4 $3.6M 94k 38.82
Ptc Therapeutics 0.4 $3.7M 600.00 6085.00
Intra Cellular Therapies (ITCI) 0.4 $3.6M 150k 23.88
TJX Companies (TJX) 0.3 $3.3M 47k 70.04
Prothena (PRTA) 0.3 $3.4M 88k 38.14
Esperion Therapeutics (ESPR) 0.3 $3.3M 36k 92.61
Dyax Corp cmn 0.3 $3.4M 2.0k 1675.50
iShares MSCI Germany Index Fund (EWG) 0.3 $3.2M 108k 29.84
Puma Biotechnology (PBYI) 0.3 $3.3M 14k 236.08
Sage Therapeutics (SAGE) 0.3 $3.3M 66k 50.23
V.F. Corporation (VFC) 0.3 $3.2M 42k 75.31
Orbotech Ltd Com Stk 0.3 $3.2M 197k 16.03
Aegerion Pharmaceuticals 0.3 $3.1M 120k 26.17
Sunesis Pharmaceuticals 0.3 $3.2M 1.3M 2.45
Gw Pharmaceuticals Plc ads 0.3 $3.2M 35k 91.14
Perrigo Company (PRGO) 0.3 $3.0M 18k 165.54
Neurocrine Biosciences (NBIX) 0.3 $3.0M 75k 39.71
Mirati Therapeutics 0.3 $2.9M 100k 29.32
Keryx Biopharmaceuticals 0.3 $2.9M 230k 12.73
Celldex Therapeutics 0.3 $2.9M 105k 27.87
Receptos 0.3 $2.9M 18k 164.91
Medicines Company 0.3 $2.8M 100k 28.02
Medicines 0.3 $2.8M 1.0k 2802.00
Tetraphase Pharmaceuticals 0.3 $2.7M 75k 36.64
Epizyme 0.3 $2.8M 150k 18.78
Aerie Pharmaceuticals 0.3 $2.8M 90k 31.34
Retrophin 0.3 $2.7M 111k 23.96
Immune Design 0.3 $2.7M 129k 21.11
Atara Biotherapeutics 0.3 $2.6M 64k 41.57
VeriFone Systems 0.3 $2.6M 76k 34.89
Trevena 0.3 $2.6M 392k 6.52
Uniqure Nv (QURE) 0.3 $2.5M 102k 24.32
Otonomy 0.3 $2.5M 70k 35.36
Avalanche Biotechnologies In 0.2 $2.4M 60k 40.52
Snap-on Incorporated (SNA) 0.2 $2.3M 15k 147.07
Sangamo Biosciences (SGMO) 0.2 $2.2M 140k 15.68
Therapeuticsmd 0.2 $2.2M 365k 6.05
Inotek Pharmaceuticals 0.2 $2.2M 400k 5.42
Summit Therapeutics Plc spons ads 0.2 $2.2M 175k 12.39
priceline.com Incorporated 0.2 $2.1M 1.8k 1164.29
iShares Dow Jones US Home Const. (ITB) 0.2 $2.1M 76k 28.22
Stericycle (SRCL) 0.2 $2.0M 15k 140.41
Wabtec Corporation (WAB) 0.2 $2.0M 22k 95.02
Union Pacific Corporation (UNP) 0.2 $1.9M 18k 108.30
Ellomay Capital (ELLO) 0.2 $1.9M 222k 8.50
Macrogenics (MGNX) 0.2 $1.9M 60k 31.37
Marinus Pharmaceuticals 0.2 $1.9M 214k 8.99
Trillium Therapeutics, Inc. Cmn 0.2 $1.9M 95k 20.23
Transition Therapeutics 0.2 $1.9M 273k 6.83
Foamix Pharmaceuticals 0.2 $1.9M 200k 9.25
Zosano Pharma 0.2 $1.9M 185k 10.11
Gentherm (THRM) 0.2 $1.7M 35k 50.51
Cellectis S A (CLLS) 0.2 $1.7M 50k 34.58
Tokai Pharmaceuticals 0.2 $1.7M 146k 11.30
Mannkind Corp Common Stock cmn 0.2 $1.6M 3.0k 520.00
Genvec 0.2 $1.6M 528k 2.95
Galectin Therapeutics (GALT) 0.2 $1.5M 450k 3.35
Conatus Pharmaceuticals 0.2 $1.6M 220k 7.12
Ocera Therapeutics 0.2 $1.5M 321k 4.71
Medgenics 0.1 $1.4M 175k 8.06
Genocea Biosciences 0.1 $1.5M 124k 11.86
Newlink Genetics Corporation 0.1 $1.4M 25k 54.72
Assembly Biosciences 0.1 $1.3M 100k 13.24
Exelixis (EXEL) 0.1 $1.3M 500k 2.57
Ascendis Pharma A S (ASND) 0.1 $1.2M 70k 17.36
Immunomedics 0.1 $1.1M 300k 3.83
Sagent Pharmaceuticals 0.1 $1.2M 50k 23.26
D Stemline Therapeutics 0.1 $1.2M 81k 14.46
Heron Therapeutics (HRTX) 0.1 $1.2M 80k 14.56
Aldeyra Therapeutics (ALDX) 0.1 $1.2M 115k 10.38
Palatin Technologies 0.1 $1.1M 1.0M 1.02
Cymabay Therapeutics 0.1 $1.1M 157k 6.92
Auris Med Hldg 0.1 $997k 186k 5.35
Juno Therapeutics 0.1 $910k 15k 60.67
Eleven Biotherapeutics 0.1 $777k 87k 8.92
Achillion Pharmaceuticals 0.1 $646k 66k 9.86
Mast Therapeutics 0.1 $674k 1.4M 0.49
Sapiens Intl Corp N V 0.1 $463k 56k 8.21
Ohr Pharmaceutical 0.1 $476k 188k 2.54
Biolinerx Ltd-spons 0.0 $408k 193k 2.11
Spectrum Pharmaceuticals 0.0 $304k 50k 6.08
Alcobra 0.0 $1.0k 200.00 5.00
Lumenis Ltd shs cl b 0.0 $0 245.00 0.00