Sphera Funds Management

Sphera Funds Management as of Dec. 31, 2015

Portfolio Holdings for Sphera Funds Management

Sphera Funds Management holds 118 positions in its portfolio as reported in the December 2015 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Spdr S&p 500 Etf Tr option 11.9 $82M 400k 203.87
Teva Pharmaceutical Industries (TEVA) 7.5 $52M 785k 65.64
Ormat Technologies (ORA) 5.7 $39M 273k 142.20
Pfizer (PFE) 5.6 $38M 1.2M 32.28
Biogen Idec (BIIB) 5.6 $38M 124k 306.35
Allergan 4.6 $31M 100k 312.50
Spdr S&p Oil & Gas Exp & Pr put 3.4 $23M 330k 70.20
Abbvie (ABBV) 3.1 $21M 362k 59.24
Celgene Corporation 2.6 $18M 147k 119.76
Mylan N V call 2.4 $16M 300k 54.07
Gilead Sciences (GILD) 2.1 $14M 143k 101.19
Alexion Pharmaceuticals 1.6 $11M 59k 190.76
Bristol Myers Squibb (BMY) 1.2 $8.4M 122k 68.79
Shire 1.2 $8.2M 40k 205.00
Acorda Therapeutics 0.9 $6.1M 143k 42.78
Vertex Pharmaceuticals Incorporated (VRTX) 0.9 $6.1M 48k 125.83
Five Prime Therapeutics 0.9 $6.0M 145k 41.50
Google 0.8 $5.8M 7.4k 777.97
Incyte Corporation (INCY) 0.8 $5.6M 52k 108.44
Sage Therapeutics (SAGE) 0.8 $5.4M 93k 58.30
Cellcom Israel (CELJF) 0.8 $5.1M 212k 24.23
Opko Health (OPK) 0.7 $5.0M 500k 10.05
Ionis Pharmaceuticals (IONS) 0.7 $5.0M 81k 61.93
Macrogenics (MGNX) 0.7 $4.7M 153k 30.97
Bellicum Pharma 0.7 $4.7M 232k 20.27
CHECK POINT SOFTWARE Technolog Com Stk (CHKP) 0.7 $4.5M 56k 81.39
Portola Pharmaceuticals 0.6 $4.4M 86k 51.45
Marinus Pharmaceuticals 0.6 $4.4M 571k 7.64
Vanda Pharmaceuticals (VNDA) 0.6 $4.3M 462k 9.31
Radius Health 0.6 $4.3M 70k 61.54
Adamas Pharmaceuticals 0.6 $4.2M 150k 28.32
Inotek Pharmaceuticals 0.6 $4.1M 360k 11.33
Alnylam Pharmaceuticals (ALNY) 0.6 $3.8M 40k 94.15
Orbotech Ltd Com Stk 0.5 $3.7M 168k 22.13
Alder Biopharmaceuticals 0.5 $3.7M 113k 33.03
Heron Therapeutics (HRTX) 0.5 $3.6M 135k 26.70
Kempharm 0.5 $3.7M 184k 19.86
Google Inc option 0.5 $3.6M 4.6k 778.04
ACADIA Pharmaceuticals (ACAD) 0.5 $3.6M 100k 35.65
Catalyst Pharmaceutical Partners (CPRX) 0.5 $3.6M 1.5M 2.45
Raptor Pharmaceutical 0.5 $3.6M 685k 5.20
Gw Pharmaceuticals Plc ads 0.5 $3.5M 50k 69.44
TJX Companies (TJX) 0.5 $3.4M 48k 70.91
Valeant Pharmaceuticals Int 0.5 $3.4M 34k 101.66
Anacor Pharmaceuticals In 0.5 $3.4M 30k 112.97
Concert Pharmaceuticals I equity 0.5 $3.4M 180k 18.97
Novavax 0.5 $3.4M 400k 8.39
Cara Therapeutics (CARA) 0.5 $3.3M 198k 16.86
Aduro Biotech 0.5 $3.4M 120k 28.14
Clovis Oncology 0.5 $3.3M 95k 35.01
Agios Pharmaceuticals (AGIO) 0.5 $3.2M 50k 64.92
Egalet 0.5 $3.2M 293k 11.02
Seattle Genetics 0.5 $3.1M 70k 44.89
Mondelez Int (MDLZ) 0.5 $3.1M 69k 44.84
Kite Pharma 0.5 $3.1M 50k 61.62
Immune Design 0.5 $3.1M 153k 20.08
MasterCard Incorporated (MA) 0.4 $3.0M 31k 97.37
Arrowhead Research 0.4 $3.0M 486k 6.15
Acceleron Pharma 0.4 $2.9M 60k 48.77
Visa (V) 0.4 $2.8M 37k 77.54
Genocea Biosciences 0.4 $2.8M 541k 5.27
Starbucks Corporation (SBUX) 0.4 $2.8M 47k 60.03
Foamix Pharmaceuticals 0.4 $2.8M 342k 8.11
Partner Communications Company 0.4 $2.7M 618k 4.37
Biotie Therapies Corp. ads 0.4 $2.7M 194k 14.15
Honeywell International (HON) 0.4 $2.7M 26k 103.57
Retrophin 0.4 $2.6M 135k 19.29
Intra Cellular Therapies (ITCI) 0.4 $2.6M 48k 53.78
Exelixis (EXEL) 0.4 $2.5M 450k 5.64
Uniqure Nv (QURE) 0.4 $2.5M 154k 16.54
Colucid Pharmaceuticals 0.3 $2.4M 286k 8.37
Advance Auto Parts (AAP) 0.3 $2.3M 16k 150.50
Halozyme Therapeutics (HALO) 0.3 $2.3M 135k 17.33
Forward Pharma A/s 0.3 $2.3M 122k 19.00
Summit Therapeutics Plc spons ads 0.3 $2.3M 202k 11.48
Medicines Company 0.3 $2.2M 60k 37.33
Dimension Therapeutics 0.3 $2.3M 200k 11.28
Cognizant Technology Solutions (CTSH) 0.3 $2.2M 37k 60.03
Vitae Pharmaceuticals 0.3 $2.2M 120k 18.10
Dynavax Technologies (DVAX) 0.3 $2.2M 90k 24.16
Ptc Therapeutics I (PTCT) 0.3 $2.1M 66k 32.40
Palatin Technologies 0.3 $2.1M 3.1M 0.66
Abeona Therapeutics 0.3 $2.0M 600k 3.36
Cynapsus Therapeutics 0.3 $2.1M 134k 15.44
Arbutus Biopharma (ABUS) 0.3 $2.0M 455k 4.45
Axsome Therapeutics (AXSM) 0.3 $2.0M 220k 9.13
Scynexis 0.3 $1.9M 305k 6.21
Tobira Therapeutics Inc Common Stock Usd 0.0001 0.3 $1.9M 188k 10.05
Edge Therapeutics 0.3 $1.9M 155k 12.50
Pieris Pharmaceuticals 0.3 $1.9M 810k 2.29
Nivalis Therapeutics 0.3 $1.8M 232k 7.74
Ocera Therapeutics 0.2 $1.7M 550k 3.12
Gw Pharmaceuticals Plc ads 0.2 $1.7M 24k 69.44
Aldeyra Therapeutics (ALDX) 0.2 $1.6M 239k 6.78
Trillium Therapeutics, Inc. Cmn 0.2 $1.7M 132k 12.61
Novartis (NVS) 0.2 $1.5M 18k 86.06
Tesaro 0.2 $1.6M 31k 52.30
Axalta Coating Sys (AXTA) 0.2 $1.5M 56k 26.65
Nabriva Therapeutics 0.2 $1.5M 158k 9.55
Nxp Semiconductors N V (NXPI) 0.2 $1.4M 17k 84.28
Strongbridge Bioph shs usd 0.2 $1.4M 182k 7.60
Loxo Oncology 0.2 $1.3M 45k 28.44
Proqr Thrapeutics N V shs euro (PRQR) 0.2 $1.3M 150k 8.68
Carbylan Therapeutics Inc Common Stock Usd 0.001 0.2 $1.3M 360k 3.62
Mannkind Corp 0.2 $1.1M 760k 1.45
Array BioPharma 0.1 $907k 215k 4.22
Wabtec Corporation (WAB) 0.1 $908k 13k 71.15
Delphi Automotive 0.1 $863k 10k 85.74
Ellomay Capital (ELLO) 0.1 $824k 96k 8.61
Wix (WIX) 0.1 $807k 36k 22.76
Charter Communications 0.1 $737k 4.0k 183.06
Catabasis Pharmaceuticals 0.1 $640k 81k 7.93
Ezchip Semiconductor Lt 0.1 $505k 20k 24.70
BioMarin Pharmaceutical (BMRN) 0.1 $388k 3.7k 104.86
Genvec 0.1 $343k 187k 1.84
Atyr Pharma Inc Common Stock Usd 0.001 0.1 $358k 37k 9.82
Israel Chemicals 0.0 $280k 69k 4.05
A. O. Smith Corporation (AOS) 0.0 $207k 2.7k 76.67