Hambrecht & Quist Capital Management

Tekla Capital Management as of Sept. 30, 2019

Portfolio Holdings for Tekla Capital Management

Tekla Capital Management holds 192 positions in its portfolio as reported in the September 2019 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Celgene Corporation 6.4 $146M 1.5M 99.30
Amgen (AMGN) 5.3 $122M 632k 193.51
Gilead Sciences (GILD) 5.1 $116M 1.8M 63.38
Johnson & Johnson (JNJ) 4.6 $106M 818k 129.38
Merck & Co (MRK) 4.5 $102M 1.2M 84.18
Vertex Pharmaceuticals Incorporated (VRTX) 3.6 $83M 487k 169.42
Pfizer (PFE) 3.3 $76M 2.1M 35.93
UnitedHealth (UNH) 3.2 $73M 337k 217.32
Illumina (ILMN) 3.2 $73M 241k 304.22
Biogen Idec (BIIB) 2.6 $60M 258k 232.82
Alexion Pharmaceuticals 1.9 $45M 454k 97.94
Regeneron Pharmaceuticals (REGN) 1.9 $44M 160k 277.40
Medtronic (MDT) 1.9 $43M 399k 108.62
Bristol Myers Squibb (BMY) 1.6 $37M 738k 50.71
CVS Caremark Corporation (CVS) 1.5 $34M 540k 63.07
Zoetis Inc Cl A (ZTS) 1.4 $31M 249k 124.59
Abbvie (ABBV) 1.3 $30M 400k 75.72
Intuitive Surgical (ISRG) 1.3 $30M 56k 539.94
Incyte Corporation (INCY) 1.3 $29M 394k 74.23
Anthem (ELV) 1.3 $29M 121k 240.10
Abbott Laboratories (ABT) 1.2 $27M 323k 83.67
Thermo Fisher Scientific (TMO) 1.1 $26M 89k 291.27
Stryker Corporation (SYK) 1.1 $26M 119k 216.30
Seattle Genetics 1.1 $25M 290k 85.40
Allergan 1.1 $24M 145k 168.29
Boston Scientific Corporation (BSX) 1.0 $23M 565k 40.69
Danaher Corporation (DHR) 1.0 $22M 152k 144.43
Novartis (NVS) 0.9 $22M 249k 86.90
Humana (HUM) 0.9 $22M 84k 255.67
Mylan Nv 0.9 $21M 1.0M 19.78
Cigna Corp (CI) 0.8 $19M 125k 151.79
Neurocrine Biosciences (NBIX) 0.8 $19M 207k 90.11
Eli Lilly & Co. (LLY) 0.8 $18M 157k 111.83
BioMarin Pharmaceutical (BMRN) 0.7 $17M 246k 67.40
Pra Health Sciences 0.7 $15M 153k 99.23
Becton, Dickinson and (BDX) 0.6 $15M 58k 252.95
McKesson Corporation (MCK) 0.6 $15M 107k 136.66
Baxter International (BAX) 0.6 $14M 165k 87.47
Edwards Lifesciences (EW) 0.6 $14M 65k 219.91
AmerisourceBergen (COR) 0.6 $14M 174k 82.33
Welltower Inc Com reit (WELL) 0.6 $14M 152k 90.65
IDEXX Laboratories (IDXX) 0.6 $14M 50k 271.94
Alnylam Pharmaceuticals (ALNY) 0.6 $13M 166k 80.42
Bluebird Bio (BLUE) 0.6 $13M 140k 91.82
AstraZeneca (AZN) 0.5 $12M 276k 44.57
Novo Nordisk A/S (NVO) 0.5 $13M 241k 51.70
Sage Therapeutics (SAGE) 0.5 $12M 87k 140.29
Hca Holdings (HCA) 0.5 $12M 98k 120.42
Omega Healthcare Investors (OHI) 0.5 $11M 273k 41.79
Beigene (BGNE) 0.5 $12M 94k 122.46
Ionis Pharmaceuticals (IONS) 0.5 $11M 186k 59.91
Sabra Health Care REIT (SBRA) 0.5 $11M 466k 22.96
Zimmer Holdings (ZBH) 0.5 $11M 78k 137.27
Sarepta Therapeutics (SRPT) 0.5 $11M 140k 75.32
Ventas (VTR) 0.5 $10M 141k 73.03
GlaxoSmithKline 0.4 $9.9M 232k 42.68
Jazz Pharmaceuticals (JAZZ) 0.4 $9.6M 75k 128.14
Fibrogen (FGEN) 0.4 $8.6M 233k 36.98
Esperion Therapeutics (ESPR) 0.3 $7.8M 214k 36.66
Novocure Ltd ord (NVCR) 0.3 $7.5M 101k 74.78
LTC Properties (LTC) 0.3 $7.4M 145k 51.22
Gw Pharmaceuticals Plc ads 0.3 $7.4M 65k 115.03
Ascendis Pharma A S (ASND) 0.3 $7.4M 77k 96.32
Blueprint Medicines (BPMC) 0.3 $7.4M 101k 73.47
Dentsply Sirona (XRAY) 0.3 $7.3M 137k 53.31
Medicines Company 0.3 $6.8M 136k 50.00
SPDR S&P Biotech (XBI) 0.3 $6.8M 89k 76.25
Immunomedics 0.3 $6.5M 487k 13.26
Mirati Therapeutics (MRTX) 0.3 $6.2M 80k 77.90
Exelixis (EXEL) 0.3 $5.9M 332k 17.68
Smith & Nephew (SNN) 0.3 $5.9M 122k 48.13
Bio-techne Corporation (TECH) 0.3 $6.0M 31k 195.66
Horizon Therapeutics 0.3 $5.8M 215k 27.23
Abiomed 0.2 $5.8M 33k 177.89
ACADIA Pharmaceuticals (ACAD) 0.2 $5.8M 160k 35.99
Sutro Biopharma (STRO) 0.2 $5.8M 641k 9.09
Teva Pharmaceutical Industries (TEVA) 0.2 $5.4M 786k 6.88
Physicians Realty Trust (DOC) 0.2 $5.4M 304k 17.75
Laboratory Corp. of America Holdings (LH) 0.2 $5.3M 31k 167.99
Nektar Therapeutics (NKTR) 0.2 $5.2M 284k 18.21
ResMed (RMD) 0.2 $5.0M 37k 135.11
Align Technology (ALGN) 0.2 $5.1M 28k 180.92
Ptc Therapeutics I (PTCT) 0.2 $5.0M 148k 33.82
Xencor (XNCR) 0.2 $5.0M 148k 33.73
Pieris Pharmaceuticals (PIRS) 0.2 $4.9M 1.4M 3.41
Agios Pharmaceuticals (AGIO) 0.2 $4.6M 142k 32.40
Global Blood Therapeutics In 0.2 $4.5M 93k 48.52
United Therapeutics Corporation (UTHR) 0.2 $4.3M 54k 79.75
Amarin Corporation (AMRN) 0.2 $4.4M 289k 15.16
Ligand Pharmaceuticals In (LGND) 0.2 $4.4M 44k 99.53
Iqvia Holdings (IQV) 0.2 $4.5M 30k 149.38
Acadia Healthcare (ACHC) 0.2 $4.2M 136k 31.08
Epizyme 0.2 $4.1M 400k 10.32
Ultragenyx Pharmaceutical (RARE) 0.2 $4.2M 98k 42.78
Crispr Therapeutics (CRSP) 0.2 $4.2M 101k 40.99
Sanofi-Aventis SA (SNY) 0.2 $4.0M 86k 46.33
Masimo Corporation (MASI) 0.2 $3.9M 26k 148.77
Alkermes (ALKS) 0.2 $3.9M 198k 19.51
Coherus Biosciences (CHRS) 0.2 $4.0M 195k 20.26
Regenxbio Inc equity us cm (RGNX) 0.2 $3.9M 109k 35.60
Argenx Se (ARGX) 0.2 $3.9M 34k 113.96
Medical Properties Trust (MPW) 0.2 $3.7M 187k 19.56
Takeda Pharmaceutical (TAK) 0.2 $3.6M 210k 17.20
Bausch Health Companies (BHC) 0.2 $3.7M 169k 21.85
Acceleron Pharma 0.1 $3.4M 86k 39.51
Editas Medicine (EDIT) 0.1 $3.4M 148k 22.74
Flamel Technologies Sa (AVDL) 0.1 $3.4M 815k 4.16
Steris Plc Ord equities (STE) 0.1 $3.5M 25k 144.49
Charles River Laboratories (CRL) 0.1 $3.3M 25k 132.37
Senior Housing Properties Trust 0.1 $3.3M 358k 9.26
Tenet Healthcare Corporation (THC) 0.1 $3.1M 141k 22.12
Portola Pharmaceuticals 0.1 $3.1M 115k 26.82
Iovance Biotherapeutics (IOVA) 0.1 $3.2M 175k 18.20
Alcon (ALC) 0.1 $3.2M 55k 58.28
Insmed (INSM) 0.1 $2.9M 165k 17.64
Inogen (INGN) 0.1 $2.9M 62k 47.91
Cardinal Health (CAH) 0.1 $2.7M 58k 47.18
Quest Diagnostics Incorporated (DGX) 0.1 $2.8M 26k 107.03
Ardelyx (ARDX) 0.1 $2.7M 583k 4.70
Agilent Technologies Inc C ommon (A) 0.1 $2.6M 34k 76.62
Amicus Therapeutics (FOLD) 0.1 $2.5M 315k 8.02
Pacific Biosciences of California (PACB) 0.1 $2.6M 496k 5.16
Fate Therapeutics (FATE) 0.1 $2.6M 166k 15.53
Zogenix 0.1 $2.5M 62k 40.03
Wright Medical Group Nv 0.1 $2.6M 124k 20.63
Wave Life Sciences (WVE) 0.1 $2.5M 123k 20.53
Syneos Health 0.1 $2.4M 46k 53.22
Rocket Pharmaceuticals (RCKT) 0.1 $2.4M 208k 11.65
Healthcare Realty Trust Incorporated 0.1 $2.3M 68k 33.50
Intercept Pharmaceuticals In 0.1 $2.3M 34k 66.37
Anaptysbio Inc Common (ANAB) 0.1 $2.4M 68k 34.99
Apellis Pharmaceuticals (APLS) 0.1 $2.4M 99k 24.09
Hologic (HOLX) 0.1 $2.2M 43k 50.49
Koninklijke Philips Electronics NV (PHG) 0.1 $2.0M 43k 46.14
Teleflex Incorporated (TFX) 0.1 $2.2M 6.4k 339.71
Quotient 0.1 $2.0M 260k 7.77
Atreca Inc Cl A (BCEL) 0.1 $2.0M 167k 12.24
iShares NASDAQ Biotechnology Index (IBB) 0.1 $1.9M 19k 99.50
Uniqure Nv (QURE) 0.1 $1.7M 44k 39.36
Healthequity (HQY) 0.1 $1.8M 32k 57.15
PerkinElmer (RVTY) 0.1 $1.6M 19k 85.16
HCP 0.1 $1.6M 46k 35.63
Endo International (ENDPQ) 0.1 $1.7M 532k 3.21
Evolent Health (EVH) 0.1 $1.7M 231k 7.19
Aerie Pharmaceuticals 0.1 $1.3M 67k 19.22
Healthcare Tr Amer Inc cl a 0.1 $1.4M 46k 29.37
Galapagos Nv- (GLPG) 0.1 $1.4M 9.1k 152.61
Ra Pharmaceuticals 0.1 $1.3M 56k 23.64
Arena Pharmaceuticals 0.1 $1.3M 28k 45.78
New Senior Inv Grp 0.1 $1.1M 158k 6.68
Diplomat Pharmacy 0.1 $1.1M 215k 4.90
Cellectis S A (CLLS) 0.1 $1.1M 110k 10.40
Madrigal Pharmaceuticals (MDGL) 0.1 $1.2M 13k 86.21
Biohaven Pharmaceutical Holding 0.1 $1.2M 29k 41.72
Verona Pharma Plc ads (VRNA) 0.1 $1.3M 275k 4.57
Ovid Therapeutics (OVID) 0.1 $1.2M 373k 3.24
Zai Lab (ZLAB) 0.1 $1.2M 38k 32.35
Spectrum Pharmaceuticals 0.0 $951k 115k 8.29
Theravance Biopharma (TBPH) 0.0 $898k 46k 19.48
Foamix Pharmaceuticals 0.0 $914k 301k 3.04
Myokardia 0.0 $1.0M 19k 52.12
Arrowhead Pharmaceuticals (ARWR) 0.0 $865k 31k 28.18
Global Medical Reit (GMRE) 0.0 $837k 73k 11.40
Ac Immune Sa (ACIU) 0.0 $851k 172k 4.95
Molecular Templates 0.0 $950k 144k 6.59
Allakos (ALLK) 0.0 $960k 12k 78.64
Milestone Pharmaceuticals (MIST) 0.0 $812k 47k 17.30
Community Health Systems (CYH) 0.0 $734k 204k 3.60
Puma Biotechnology (PBYI) 0.0 $768k 71k 10.77
Perrigo Company (PRGO) 0.0 $605k 11k 55.93
Intellia Therapeutics (NTLA) 0.0 $735k 55k 13.35
ArQule 0.0 $545k 76k 7.17
Myriad Genetics (MYGN) 0.0 $538k 19k 28.61
ImmunoGen (IMGN) 0.0 $407k 168k 2.42
Cymabay Therapeutics (CBAY) 0.0 $451k 88k 5.12
Merus N V (MRUS) 0.0 $382k 21k 17.83
Zymeworks 0.0 $377k 15k 24.82
Intra Cellular Therapies (ITCI) 0.0 $206k 28k 7.48
Trillium Therapeutics, Inc. Cmn 0.0 $138k 446k 0.31
Adaptimmune Therapeutics (ADAP) 0.0 $116k 77k 1.51
Cidara Therapeutics Inc Common Stock Usd 0.0001 (CDTX) 0.0 $318k 159k 2.00
Aerpio Pharmaceuticals 0.0 $175k 258k 0.68
Avrobio Ord (AVRO) 0.0 $285k 20k 14.13
Magenta Therapeutics 0.0 $172k 17k 10.26
Novavax (NVAX) 0.0 $143k 29k 5.01
Arca Biopharma (ABIO) 0.0 $192k 36k 5.32
Tetraphase Pharms 0.0 $229k 43k 5.33
Mallinckrodt Pub 0.0 $79k 33k 2.40
Bellicum Pharma 0.0 $63k 60k 1.05
Quorum Health 0.0 $29k 24k 1.22
Clearside Biomedical (CLSD) 0.0 $104k 165k 0.63
Celldex Therapeutics (CLDX) 0.0 $15k 7.1k 2.13