Hambrecht & Quist Capital Management

Tekla Capital Management as of Dec. 31, 2019

Portfolio Holdings for Tekla Capital Management

Tekla Capital Management holds 214 positions in its portfolio as reported in the December 2019 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Amgen (AMGN) 5.6 $149M 617k 241.07
Johnson & Johnson (JNJ) 5.1 $134M 917k 145.87
Gilead Sciences (GILD) 4.7 $123M 1.9M 64.98
Merck & Co (MRK) 4.2 $110M 1.2M 90.95
Vertex Pharmaceuticals Incorporated (VRTX) 4.1 $108M 494k 218.95
Illumina (ILMN) 3.4 $90M 273k 331.74
Biogen Idec (BIIB) 3.2 $85M 285k 296.73
Pfizer (PFE) 3.1 $82M 2.1M 39.18
Regeneron Pharmaceuticals (REGN) 2.9 $76M 201k 375.48
UnitedHealth (UNH) 2.8 $73M 249k 293.98
Medtronic (MDT) 2.0 $53M 471k 113.45
Bristol Myers Squibb (BMY) 1.9 $50M 775k 64.19
Alexion Pharmaceuticals 1.8 $47M 436k 108.15
Abbott Laboratories (ABT) 1.6 $41M 472k 86.86
Thermo Fisher Scientific (TMO) 1.5 $40M 123k 324.87
Cigna Corp (CI) 1.5 $39M 191k 204.49
CVS Caremark Corporation (CVS) 1.4 $37M 498k 74.29
Incyte Corporation (INCY) 1.3 $34M 383k 87.32
Seattle Genetics 1.2 $32M 277k 114.26
Anthem (ELV) 1.2 $31M 102k 302.03
Allergan 1.1 $31M 160k 191.17
Abbvie (ABBV) 1.1 $30M 341k 88.54
Eli Lilly & Co. (LLY) 1.0 $28M 210k 131.43
Boston Scientific Corporation (BSX) 1.0 $26M 564k 45.22
Danaher Corporation (DHR) 1.0 $25M 166k 153.48
Zoetis Inc Cl A (ZTS) 0.9 $25M 190k 132.35
Stryker Corporation (SYK) 0.9 $24M 114k 209.94
Sarepta Therapeutics (SRPT) 0.9 $23M 182k 129.04
BioMarin Pharmaceutical (BMRN) 0.9 $23M 277k 84.55
Intuitive Surgical (ISRG) 0.9 $23M 39k 591.14
Mylan Nv 0.8 $21M 1.0M 20.10
Neurocrine Biosciences (NBIX) 0.8 $21M 193k 107.49
Novartis (NVS) 0.8 $20M 211k 94.69
Humana (HUM) 0.8 $20M 55k 366.51
Becton, Dickinson and (BDX) 0.7 $18M 66k 271.97
Pra Health Sciences 0.6 $17M 153k 111.15
Alnylam Pharmaceuticals (ALNY) 0.6 $17M 144k 115.17
Edwards Lifesciences (EW) 0.6 $16M 70k 233.29
Welltower Inc Com reit (WELL) 0.6 $16M 192k 81.78
Hca Holdings (HCA) 0.5 $14M 96k 147.81
AstraZeneca (AZN) 0.5 $14M 276k 49.86
Beigene 0.5 $13M 81k 165.76
Novo Nordisk A/S (NVO) 0.5 $13M 221k 57.88
Jazz Pharmaceuticals (JAZZ) 0.5 $13M 86k 149.28
Esperion Therapeutics (ESPR) 0.5 $13M 214k 59.63
Ionis Pharmaceuticals (IONS) 0.5 $13M 210k 60.41
GlaxoSmithKline 0.5 $12M 257k 46.99
Omega Healthcare Investors (OHI) 0.5 $12M 285k 42.35
Milestone Pharmaceuticals (MIST) 0.5 $12M 747k 16.01
Global Blood Therapeutics In 0.4 $12M 147k 79.49
IDEXX Laboratories (IDXX) 0.4 $11M 44k 261.13
Ventas (VTR) 0.4 $11M 191k 57.74
Bio-techne Corporation (TECH) 0.4 $11M 50k 219.50
Horizon Therapeutics 0.4 $11M 305k 36.20
Baxter International (BAX) 0.4 $11M 130k 83.62
Medicines Company 0.4 $10M 121k 84.94
Immunomedics 0.4 $10M 487k 21.16
Agios Pharmaceuticals (AGIO) 0.4 $10M 216k 47.75
Sabra Health Care REIT (SBRA) 0.4 $9.9M 466k 21.34
AmerisourceBergen (COR) 0.4 $9.8M 116k 85.02
Zimmer Holdings (ZBH) 0.4 $9.5M 64k 149.68
Centene Corporation (CNC) 0.4 $9.4M 150k 62.87
Ascendis Pharma A S (ASND) 0.4 $9.6M 69k 139.11
McKesson Corporation (MCK) 0.3 $9.3M 67k 138.31
Sanofi-Aventis SA (SNY) 0.3 $9.4M 187k 50.20
ACADIA Pharmaceuticals (ACAD) 0.3 $9.3M 218k 42.78
Mirati Therapeutics 0.3 $9.1M 71k 128.86
Blueprint Medicines (BPMC) 0.3 $9.4M 117k 80.11
Exelixis (EXEL) 0.3 $9.1M 515k 17.62
Novocure Ltd ord (NVCR) 0.3 $9.1M 107k 84.27
Amarin Corporation (AMRN) 0.3 $8.8M 408k 21.44
Epizyme 0.3 $8.7M 353k 24.60
Physicians Realty Trust 0.3 $8.7M 457k 18.94
Bluebird Bio (BLUE) 0.3 $8.4M 96k 87.75
Fibrogen (FGEN) 0.3 $8.3M 194k 42.89
Atreca Inc Cl A (BCEL) 0.3 $8.1M 525k 15.47
Medical Properties Trust (MPW) 0.3 $7.9M 374k 21.11
Teva Pharmaceutical Industries (TEVA) 0.3 $7.7M 786k 9.80
LTC Properties (LTC) 0.3 $7.4M 166k 44.77
Argenx Se (ARGX) 0.3 $7.2M 45k 160.53
Sutro Biopharma (STRO) 0.3 $7.1M 641k 11.00
Sage Therapeutics (SAGE) 0.3 $6.9M 96k 72.19
Dentsply Sirona (XRAY) 0.3 $6.8M 120k 56.59
Syneos Health 0.3 $6.9M 116k 59.48
Allakos (ALLK) 0.3 $6.8M 71k 95.36
Arrowhead Pharmaceuticals (ARWR) 0.2 $6.7M 105k 63.43
Iovance Biotherapeutics (IOVA) 0.2 $6.7M 244k 27.68
Align Technology (ALGN) 0.2 $6.2M 22k 279.02
SPDR S&P Biotech (XBI) 0.2 $6.5M 68k 95.11
Nektar Therapeutics (NKTR) 0.2 $6.1M 284k 21.58
Flamel Technologies Sa 0.2 $6.2M 815k 7.55
Teleflex Incorporated (TFX) 0.2 $5.9M 16k 376.41
Health Care SPDR (XLV) 0.2 $5.5M 54k 101.85
Abiomed 0.2 $5.6M 33k 170.59
Zogenix 0.2 $5.6M 108k 52.13
Iqvia Holdings (IQV) 0.2 $5.5M 36k 154.52
Galera Therapeutics (GRTX) 0.2 $5.5M 417k 13.16
Laboratory Corp. of America Holdings 0.2 $5.3M 31k 169.17
Gw Pharmaceuticals Plc ads 0.2 $5.2M 50k 104.57
Pieris Pharmaceuticals 0.2 $5.2M 1.4M 3.62
Reata Pharmaceuticals Inc Cl A 0.2 $5.4M 26k 204.41
Xencor (XNCR) 0.2 $5.1M 148k 34.39
Uniqure Nv (QURE) 0.2 $5.1M 71k 71.67
iShares NASDAQ Biotechnology Index (IBB) 0.2 $4.7M 39k 120.51
United Therapeutics Corporation (UTHR) 0.2 $4.8M 54k 88.09
Smith & Nephew (SNN) 0.2 $4.8M 100k 48.07
Ptc Therapeutics I (PTCT) 0.2 $4.8M 99k 48.03
Crispr Therapeutics (CRSP) 0.2 $4.6M 76k 60.90
Rocket Pharmaceuticals (RCKT) 0.2 $4.7M 208k 22.76
ArQule 0.2 $4.4M 220k 19.96
Acadia Healthcare (ACHC) 0.2 $4.5M 136k 33.22
Acceleron Pharma 0.2 $4.6M 86k 53.02
Ardelyx (ARDX) 0.2 $4.6M 608k 7.51
Editas Medicine (EDIT) 0.2 $4.4M 148k 29.61
Peak (DOC) 0.2 $4.4M 129k 34.47
Rts/bristol-myers Squibb Compa 0.2 $4.4M 1.5M 3.01
ResMed (RMD) 0.2 $4.3M 28k 154.96
Ligand Pharmaceuticals In (LGND) 0.2 $4.3M 41k 104.29
Takeda Pharmaceutical (TAK) 0.2 $4.1M 210k 19.73
Tenet Healthcare Corporation (THC) 0.2 $4.3M 113k 38.03
Intercept Pharmaceuticals In 0.2 $4.3M 34k 123.93
Ultragenyx Pharmaceutical (RARE) 0.2 $4.2M 98k 42.71
Bausch Health Companies (BHC) 0.2 $4.2M 139k 29.92
Insmed (INSM) 0.1 $3.9M 165k 23.88
Alkermes (ALKS) 0.1 $4.0M 198k 20.40
Portola Pharmaceuticals 0.1 $3.9M 162k 23.88
Apellis Pharmaceuticals (APLS) 0.1 $4.0M 131k 30.62
Amicus Therapeutics (FOLD) 0.1 $3.6M 369k 9.74
Deciphera Pharmaceuticals 0.1 $3.8M 61k 62.25
Mettler-Toledo International (MTD) 0.1 $3.3M 4.2k 793.27
Masimo Corporation (MASI) 0.1 $3.4M 22k 158.04
Inogen (INGN) 0.1 $3.5M 51k 68.34
Charles River Laboratories (CRL) 0.1 $3.2M 21k 152.76
Fate Therapeutics (FATE) 0.1 $3.2M 166k 19.57
Intra Cellular Therapies (ITCI) 0.1 $3.2M 94k 34.31
Theravance Biopharma (TBPH) 0.1 $3.0M 118k 25.89
Alcon (ALC) 0.1 $3.1M 55k 56.57
Healthcare Realty Trust Incorporated 0.1 $2.8M 84k 33.37
Diversified Healthcare Trust (DHC) 0.1 $3.0M 358k 8.44
Pacific Biosciences of California (PACB) 0.1 $2.5M 496k 5.14
Ra Pharmaceuticals 0.1 $2.6M 56k 46.93
Agilent Technologies Inc C ommon (A) 0.1 $2.3M 27k 85.31
Endo International 0.1 $2.5M 532k 4.69
Quotient 0.1 $2.5M 260k 9.51
Healthequity (HQY) 0.1 $2.4M 32k 74.06
Coherus Biosciences (CHRS) 0.1 $2.3M 125k 18.00
Steris Plc Ord equities (STE) 0.1 $2.3M 15k 152.40
Hologic (HOLX) 0.1 $2.2M 43k 52.20
Koninklijke Philips Electronics NV (PHG) 0.1 $2.1M 43k 48.81
Quest Diagnostics Incorporated (DGX) 0.1 $2.2M 21k 106.78
Evolent Health (EVH) 0.1 $2.1M 231k 9.05
Allogene Therapeutics (ALLO) 0.1 $2.1M 80k 25.98
PerkinElmer (RVTY) 0.1 $1.8M 19k 97.10
Aurinia Pharmaceuticals (AUPH) 0.1 $1.8M 91k 20.26
Cellectis S A (CLLS) 0.1 $1.9M 110k 17.12
Anaptysbio Inc Common (ANAB) 0.1 $1.9M 118k 16.25
Aerie Pharmaceuticals 0.1 $1.6M 67k 24.17
Global Medical Reit (GMRE) 0.1 $1.6M 118k 13.23
Medpace Hldgs (MEDP) 0.1 $1.6M 19k 84.04
Ac Immune Sa (ACIU) 0.1 $1.5M 172k 8.52
Biohaven Pharmaceutical Holding 0.1 $1.6M 29k 54.45
Verona Pharma Plc ads (VRNA) 0.1 $1.6M 275k 5.75
Ovid Therapeutics (OVID) 0.1 $1.5M 373k 4.15
Zai Lab (ZLAB) 0.1 $1.6M 38k 41.60
Avrobio Ord (AVRO) 0.1 $1.5M 75k 20.13
Sangamo Biosciences (SGMO) 0.1 $1.3M 150k 8.37
Heron Therapeutics (HRTX) 0.1 $1.4M 60k 23.50
Revance Therapeutics (RVNC) 0.1 $1.4M 86k 16.23
New Senior Inv Grp 0.1 $1.2M 158k 7.65
Healthcare Tr Amer Inc cl a 0.1 $1.4M 46k 30.28
Xenon Pharmaceuticals (XENE) 0.1 $1.3M 97k 13.11
Dermira 0.1 $1.4M 89k 15.16
Galapagos Nv- (GLPG) 0.1 $1.4M 6.5k 206.79
Regenxbio Inc equity us cm (RGNX) 0.1 $1.5M 36k 40.96
Myokardia 0.1 $1.4M 19k 72.90
Madrigal Pharmaceuticals (MDGL) 0.1 $1.2M 13k 91.08
Arena Pharmaceuticals 0.1 $1.3M 28k 45.43
Bridgebio Pharma (BBIO) 0.1 $1.4M 39k 35.05
Foamix Pharmaceuticals 0.0 $1.0M 301k 3.33
Eidos Therapeutics 0.0 $1.1M 20k 57.40
Universal Health Realty Income Trust (UHT) 0.0 $674k 5.7k 117.38
ImmunoGen 0.0 $860k 168k 5.11
Wave Life Sciences (WVE) 0.0 $802k 100k 8.02
Intellia Therapeutics (NTLA) 0.0 $808k 55k 14.68
Zymeworks 0.0 $691k 15k 45.48
Morphosys (MOR) 0.0 $692k 19k 35.69
Axonics Modulation Technolog (AXNX) 0.0 $779k 28k 27.72
Community Health Systems (CYH) 0.0 $591k 204k 2.90
Myriad Genetics (MYGN) 0.0 $512k 19k 27.23
Spectrum Pharmaceuticals 0.0 $417k 115k 3.64
Puma Biotechnology (PBYI) 0.0 $624k 71k 8.75
Perrigo Company (PRGO) 0.0 $559k 11k 51.67
Trillium Therapeutics, Inc. Cmn 0.0 $460k 446k 1.03
Community Healthcare Tr (CHCT) 0.0 $639k 15k 42.89
Cidara Therapeutics Inc Common Stock Usd 0.0001 0.0 $610k 159k 3.84
Clearside Biomedical (CLSD) 0.0 $480k 165k 2.90
Molecular Templates 0.0 $592k 42k 13.99
Rubius Therapeutics 0.0 $650k 68k 9.51
Genmab A/s -sp (GMAB) 0.0 $369k 17k 22.34
Cymabay Therapeutics 0.0 $173k 88k 1.96
Merus N V (MRUS) 0.0 $299k 21k 14.09
Aerpio Pharmaceuticals 0.0 $162k 258k 0.63
Magenta Therapeutics 0.0 $254k 17k 15.16
Y Mabs Therapeutics (YMAB) 0.0 $354k 11k 31.26
Guardant Health (GH) 0.0 $339k 4.3k 78.24
Turning Point Therapeutics I 0.0 $354k 5.7k 62.36
Arca Biopharma (ABIO) 0.0 $206k 36k 5.71
Mallinckrodt Pub 0.0 $115k 33k 3.49
Bellicum Pharma 0.0 $77k 60k 1.28
Adaptimmune Therapeutics (ADAP) 0.0 $92k 77k 1.19
Quorum Health 0.0 $23k 24k 0.97
Celldex Therapeutics (CLDX) 0.0 $16k 7.1k 2.27
Novavax (NVAX) 0.0 $114k 29k 3.99
Tetraphase Pharms 0.0 $121k 43k 2.82