Baker Bros. Advisors

Baker Bros. Advisors as of Sept. 30, 2015

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 133 positions in its portfolio as reported in the September 2015 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Incyte Corporation (INCY) 19.9 $2.1B 20M 110.33
Seattle Genetics 12.8 $1.4B 36M 38.56
Alexion Pharmaceuticals 9.4 $1.0B 6.5M 156.39
Abbvie (ABBV) 7.2 $782M 14M 54.41
ACADIA Pharmaceuticals (ACAD) 6.3 $677M 21M 33.07
Incyte Corp Ltd conv 5.5 $598M 275M 2.18
Incyte Corp Incy Cvt 144a 0.37 convert 5.2 $559M 259M 2.16
Anacor Pharmaceuticals In 4.5 $487M 4.1M 117.71
BioMarin Pharmaceutical (BMRN) 4.0 $429M 4.1M 105.32
Genomic Health 2.7 $289M 14M 21.16
Clovis Oncology Inc note 2.500% 9/1 2.0 $216M 129M 1.67
Dbv Technologies S A (DBVT) 1.8 $194M 5.5M 35.59
BioCryst Pharmaceuticals (BCRX) 1.5 $161M 14M 11.40
Dyax 1.3 $144M 7.6M 19.09
Biomarin Pharmaceutical Inc note 1.875% 4/2 1.1 $116M 22M 5.17
Mirati Therapeutics 0.9 $102M 3.0M 34.42
Aquinox Pharmaceuticals 0.9 $95M 6.7M 14.07
Gilead Sciences conv 0.8 $90M 21M 4.31
Heron Therapeutics (HRTX) 0.7 $71M 2.9M 24.40
Cerus Corporation (CERS) 0.6 $62M 14M 4.54
Bellicum Pharma 0.6 $61M 4.2M 14.53
Acorda Therap note 1.75% 6/15 0.5 $54M 60M 0.91
Spark Therapeutics 0.5 $53M 1.3M 41.73
Invitae (NVTAQ) 0.4 $47M 6.6M 7.22
Versartis 0.3 $37M 3.2M 11.53
ImmunoGen 0.3 $34M 3.5M 9.60
Neurocrine Biosciences (NBIX) 0.3 $30M 751k 39.79
Acorda Therapeutics 0.3 $29M 1.1M 26.51
Insmed (INSM) 0.3 $29M 1.6M 18.57
Medivation 0.3 $28M 660k 42.50
Halozyme Therapeutics (HALO) 0.2 $26M 1.9M 13.43
Gilead Sciences (GILD) 0.2 $25M 250k 98.19
Progenics Pharmaceuticals 0.2 $25M 4.4M 5.72
Intra Cellular Therapies (ITCI) 0.2 $24M 609k 40.04
Idera Pharmaceuticals 0.2 $23M 7.0M 3.35
Exelixis Inc cnv 0.2 $24M 20M 1.20
Zogenix 0.2 $24M 1.8M 13.50
Atyr Pharma Inc Common Stock Usd 0.001 0.2 $24M 2.3M 10.26
XenoPort 0.2 $23M 6.5M 3.47
Sangamo Biosciences (SGMO) 0.2 $21M 3.8M 5.64
Catalyst Pharmaceutical Partners (CPRX) 0.2 $22M 7.3M 3.00
Tg Therapeutics (TGTX) 0.2 $20M 2.0M 10.08
Array BioPharma 0.2 $20M 4.3M 4.56
Aegerion Pharmaceuticals 2% Du cvbond 0.2 $20M 27M 0.75
Clovis Oncology 0.2 $19M 203k 91.96
Alder Biopharmaceuticals 0.2 $17M 513k 32.76
Derma Sciences 0.1 $16M 3.5M 4.71
Biomarin Pharmaceutical Inc note 0.750%10/1 0.1 $16M 12M 1.30
Novavax 0.1 $16M 2.2M 7.07
Foamix Pharmaceuticals 0.1 $15M 2.0M 7.33
Galapagos Nv- (GLPG) 0.1 $15M 369k 40.71
Achillion Pharmaceuticals 0.1 $14M 2.0M 6.91
Repros Therapeutics 0.1 $15M 2.0M 7.43
Proqr Thrapeutics N V shs euro (PRQR) 0.1 $14M 988k 14.57
Zafgen 0.1 $13M 390k 31.95
Threshold Pharmaceuticals 0.1 $12M 2.9M 4.07
Bluebird Bio (BLUE) 0.1 $12M 141k 85.55
La Jolla Pharmaceuticl Com Par 0.1 $11M 412k 27.79
Ultragenyx Pharmaceutical (RARE) 0.1 $12M 124k 96.31
Xencor (XNCR) 0.1 $11M 872k 12.23
Lion Biotechnologies 0.1 $11M 1.8M 5.76
Osiris Therapeutics 0.1 $9.2M 499k 18.47
Alcobra 0.1 $9.9M 1.6M 6.04
Concert Pharmaceuticals I equity 0.1 $9.3M 496k 18.77
Akari Therapeutics 0.1 $9.5M 396k 23.99
Global Blood Therapeutics In 0.1 $8.4M 200k 42.16
Agios Pharmaceuticals (AGIO) 0.1 $7.1M 100k 70.59
Macrogenics (MGNX) 0.1 $7.4M 348k 21.42
Ascendis Pharma A S (ASND) 0.1 $7.7M 436k 17.70
Ligand Pharmaceuticals In (LGND) 0.1 $6.3M 73k 85.66
Endocyte 0.1 $6.2M 1.4M 4.58
Neuroderm Ltd F 0.1 $6.3M 305k 20.67
Dermira 0.1 $6.4M 275k 23.34
Aimmune Therapeutics 0.1 $6.3M 250k 25.32
Arrowhead Research 0.1 $5.8M 1.0M 5.76
Aerie Pharmaceuticals 0.1 $5.3M 299k 17.74
Ignyta 0.1 $5.0M 571k 8.78
Curis 0.0 $4.0M 2.0M 2.02
Amarin Corporation (AMRN) 0.0 $4.3M 2.2M 1.93
Chimerix (CMRX) 0.0 $4.4M 115k 38.20
Trevena 0.0 $4.7M 450k 10.35
Sage Therapeutics (SAGE) 0.0 $4.4M 105k 42.32
Proteon Therapeutics 0.0 $3.8M 275k 13.91
Pronai Therapeutics 0.0 $4.1M 200k 20.52
Omeros Corporation (OMER) 0.0 $3.7M 336k 10.96
Cytrx 0.0 $3.1M 1.3M 2.37
Enanta Pharmaceuticals (ENTA) 0.0 $2.7M 75k 36.13
Mast Therapeutics 0.0 $2.7M 4.7M 0.58
D Stemline Therapeutics 0.0 $2.9M 334k 8.83
Epizyme 0.0 $3.0M 233k 12.86
Array Biopharma Inc note 3.000% 6/0 0.0 $2.9M 3.0M 0.97
Juno Therapeutics 0.0 $3.3M 80k 40.69
Seres Therapeutics (MCRB) 0.0 $3.7M 125k 29.64
Natera (NTRA) 0.0 $2.7M 250k 10.85
Nabriva Therapeutics 0.0 $3.3M 350k 9.50
ISIS Pharmaceuticals 0.0 $2.3M 57k 40.43
Ironwood Pharmaceuticals (IRWD) 0.0 $1.8M 169k 10.42
Palatin Technologies 0.0 $1.7M 2.1M 0.81
Sunesis Pharmaceuticals 0.0 $2.6M 3.2M 0.81
Karyopharm Therapeutics (KPTI) 0.0 $2.3M 217k 10.53
Mediwound Ltd cmn 0.0 $1.7M 225k 7.63
Vitae Pharmaceuticals 0.0 $2.1M 188k 11.01
Immune Design 0.0 $1.8M 149k 12.20
Loxo Oncology 0.0 $1.7M 100k 17.48
Aurinia Pharmaceuticals (AUPH) 0.0 $2.0M 712k 2.81
Marinus Pharmaceuticals 0.0 $1.7M 200k 8.34
Assembly Biosciences 0.0 $2.4M 250k 9.56
Affimed Therapeutics B V 0.0 $2.5M 400k 6.17
Dynavax Technologies (DVAX) 0.0 $1.8M 75k 24.55
Protalix Biotherapeutics Inc note 4.500% 9/1 0.0 $2.5M 3.4M 0.72
Bellerophon Therapeutics 0.0 $1.8M 353k 5.19
Alnylam Pharmaceuticals (ALNY) 0.0 $911k 11k 80.34
BioDelivery Sciences International 0.0 $1.2M 210k 5.56
Discovery Laboratories 0.0 $1.1M 3.6M 0.30
Ohr Pharmaceutical 0.0 $1.0M 370k 2.76
Acceleron Pharma 0.0 $716k 29k 24.89
Ophthotech 0.0 $1.4M 36k 40.51
Achaogen 0.0 $576k 100k 5.76
Uniqure Nv (QURE) 0.0 $614k 30k 20.47
Aldeyra Therapeutics (ALDX) 0.0 $828k 142k 5.83
Tenax Therapeutics 0.0 $1.3M 420k 3.00
Trillium Therapeutics, Inc. Cmn 0.0 $821k 63k 13.03
Cellectis S A (CLLS) 0.0 $1.3M 50k 26.36
Adaptimmune Therapeutics (ADAP) 0.0 $1.2M 100k 11.97
Arbutus Biopharma (ABUS) 0.0 $1.1M 181k 6.09
Ritter Pharmaceuticals 0.0 $820k 400k 2.05
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $62k 13k 4.68
Synergy Pharmaceuticals 0.0 $356k 67k 5.31
Chemocentryx 0.0 $297k 49k 6.05
Foundation Medicine 0.0 $385k 21k 18.43
Five Prime Therapeutics 0.0 $296k 19k 15.38
Biotime Inc wts oct 1 18 0.0 $17k 20k 0.85
Aptose Biosciences 0.0 $144k 33k 4.31