Baker Bros. Advisors

Baker Bros. Advisors as of March 31, 2016

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 134 positions in its portfolio as reported in the March 2016 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Incyte Corporation (INCY) 18.0 $1.7B 24M 72.47
Seattle Genetics 16.0 $1.5B 43M 35.09
Alexion Pharmaceuticals 9.6 $911M 6.5M 139.22
Abbvie (ABBV) 8.7 $821M 14M 57.12
ACADIA Pharmaceuticals (ACAD) 7.1 $677M 24M 27.96
Incyte Corp Ltd conv 4.5 $431M 275M 1.57
Incyte Corp Incy Cvt 144a 0.37 convert 4.2 $399M 259M 1.54
BioMarin Pharmaceutical (BMRN) 4.2 $396M 4.8M 82.48
Genomic Health 3.6 $338M 14M 24.77
Anacor Pharmaceuticals In 2.9 $274M 5.1M 53.45
Dbv Technologies S A 1.9 $179M 5.5M 32.55
Acorda Therapeutics 1.0 $97M 3.7M 26.45
Biomarin Pharmaceutical Inc note 1.875% 4/2 0.9 $90M 22M 4.01
Clovis Oncology Inc note 2.500% 9/1 0.9 $88M 129M 0.68
Gilead Sciences conv 0.9 $86M 21M 4.10
Cerus Corporation (CERS) 0.8 $80M 14M 5.93
Anacor Pharmaceuticals Inc note 2.000%10/1 0.8 $75M 42M 1.79
Xenoport Inc convertible security 0.8 $73M 100M 0.73
Mirati Therapeutics 0.7 $70M 3.3M 21.40
Aquinox Pharmaceuticals 0.7 $68M 7.8M 8.82
Acorda Therap note 1.75% 6/15 0.7 $69M 77M 0.89
Invitae (NVTAQ) 0.7 $67M 6.6M 10.23
Beigene 0.6 $56M 1.9M 29.31
Heron Therapeutics (HRTX) 0.6 $55M 2.9M 18.99
Bellicum Pharma 0.5 $46M 4.9M 9.35
BioCryst Pharmaceuticals (BCRX) 0.5 $43M 15M 2.83
ImmunoGen 0.4 $38M 4.5M 8.52
Spark Therapeutics 0.4 $37M 1.3M 29.51
Neurocrine Biosciences (NBIX) 0.4 $35M 895k 39.55
Versartis 0.3 $26M 3.2M 8.02
Sangamo Biosciences (SGMO) 0.3 $25M 4.1M 6.05
Advanced Accelerat spon ads each rep 2 ord 0.2 $22M 615k 35.02
Exelixis Inc cnv 0.2 $20M 20M 0.99
Progenics Pharmaceuticals 0.2 $19M 4.4M 4.36
Achillion Pharmaceuticals 0.2 $19M 2.5M 7.72
Insmed (INSM) 0.2 $19M 1.5M 12.67
Halozyme Therapeutics (HALO) 0.2 $18M 1.9M 9.47
Tg Therapeutics (TGTX) 0.2 $17M 2.0M 8.52
Intra Cellular Therapies (ITCI) 0.2 $17M 609k 27.80
XenoPort 0.2 $16M 3.5M 4.51
Medivation 0.2 $15M 330k 45.98
Bluebird Bio (BLUE) 0.2 $15M 353k 42.50
Idera Pharmaceuticals 0.1 $14M 7.0M 1.98
Biomarin Pharmaceutical Inc note 0.750%10/1 0.1 $14M 12M 1.16
Foamix Pharmaceuticals 0.1 $15M 2.2M 6.52
Aegerion Pharmaceuticals 2% Du cvbond 0.1 $14M 27M 0.51
Array BioPharma 0.1 $13M 4.3M 2.95
Novavax 0.1 $12M 2.4M 5.16
Agios Pharmaceuticals (AGIO) 0.1 $13M 308k 40.60
Corsicanto Ltd conv bnd 0.1 $12M 15M 0.81
Galapagos Nv- (GLPG) 0.1 $13M 303k 41.82
Omeros Corporation (OMER) 0.1 $12M 749k 15.34
Derma Sciences 0.1 $12M 3.8M 3.10
Xencor (XNCR) 0.1 $12M 872k 13.42
Exelixis (EXEL) 0.1 $10M 2.6M 4.00
Ascendis Pharma A S (ASND) 0.1 $9.4M 506k 18.55
Zogenix 0.1 $9.2M 1.0M 9.24
Global Blood Therapeutics In 0.1 $9.5M 600k 15.86
Dimension Therapeutics 0.1 $9.8M 1.3M 7.83
Alkermes (ALKS) 0.1 $8.6M 250k 34.19
Alcobra 0.1 $8.9M 2.3M 3.79
Atyr Pharma Inc Common Stock Usd 0.001 0.1 $8.4M 2.1M 3.94
Ligand Pharmaceuticals In (LGND) 0.1 $7.9M 73k 107.09
Ultragenyx Pharmaceutical (RARE) 0.1 $7.8M 124k 63.31
Sage Therapeutics (SAGE) 0.1 $7.2M 224k 32.06
Catalyst Pharmaceutical Partners (CPRX) 0.1 $6.4M 5.5M 1.17
Macrogenics (MGNX) 0.1 $6.8M 364k 18.75
Concert Pharmaceuticals I equity 0.1 $6.8M 496k 13.66
Proqr Thrapeutics N V shs euro (PRQR) 0.1 $6.6M 1.3M 4.88
Endocyte 0.1 $5.3M 1.7M 3.10
Lion Biotechnologies 0.1 $5.4M 1.1M 5.08
Dermira 0.1 $5.7M 275k 20.68
Akari Therapeutics 0.1 $5.5M 396k 14.00
Neuroderm Ltd F 0.1 $4.3M 305k 14.12
Natera (NTRA) 0.1 $4.3M 450k 9.52
Arrowhead Pharmaceuticals (ARWR) 0.1 $4.9M 1.0M 4.82
Medgenics 0.0 $3.4M 765k 4.40
Aerie Pharmaceuticals 0.0 $3.6M 299k 12.16
Trevena 0.0 $3.7M 450k 8.27
Ignyta 0.0 $3.9M 571k 6.77
Vitae Pharmaceuticals 0.0 $4.2M 638k 6.63
Loxo Oncology 0.0 $3.8M 138k 27.34
Seres Therapeutics (MCRB) 0.0 $3.3M 125k 26.56
Aimmune Therapeutics 0.0 $3.4M 250k 13.56
Osiris Therapeutics 0.0 $2.9M 499k 5.71
Curis 0.0 $3.2M 2.0M 1.61
Sunesis Pharmaceuticals 0.0 $2.4M 4.5M 0.54
Epizyme 0.0 $2.8M 233k 12.12
Uniqure Nv (QURE) 0.0 $2.7M 230k 11.88
Adamas Pharmaceuticals 0.0 $2.5M 173k 14.46
Juno Therapeutics 0.0 $3.0M 80k 38.09
Invivo Therapeutics Hldgs 0.0 $2.8M 400k 6.98
Nabriva Therapeutics 0.0 $3.1M 350k 8.96
Ironwood Pharmaceuticals (IRWD) 0.0 $1.9M 169k 10.94
Cytrx 0.0 $1.8M 660k 2.68
Enanta Pharmaceuticals (ENTA) 0.0 $2.2M 75k 29.37
D Stemline Therapeutics 0.0 $1.6M 334k 4.66
Array Biopharma Inc note 3.000% 6/0 0.0 $2.4M 3.0M 0.79
Ophthotech 0.0 $1.5M 36k 42.27
Karyopharm Therapeutics (KPTI) 0.0 $1.9M 217k 8.92
Mediwound Ltd cmn 0.0 $1.8M 226k 8.07
Immune Design 0.0 $1.9M 149k 13.00
Aurinia Pharmaceuticals (AUPH) 0.0 $2.1M 712k 2.93
Affimed Therapeutics B V 0.0 $1.5M 400k 3.74
Dynavax Technologies (DVAX) 0.0 $1.4M 75k 19.24
Protalix Biotherapeutics Inc note 4.500% 9/1 0.0 $2.3M 3.4M 0.68
Proteon Therapeutics 0.0 $2.3M 299k 7.74
Trillium Therapeutics, Inc. Cmn 0.0 $2.0M 212k 9.25
Ionis Pharmaceuticals (IONS) 0.0 $2.3M 57k 40.50
Alnylam Pharmaceuticals (ALNY) 0.0 $712k 11k 62.79
BioDelivery Sciences International 0.0 $678k 210k 3.23
Amarin Corporation (AMRN) 0.0 $1.2M 802k 1.53
Palatin Technologies 0.0 $1.1M 2.1M 0.54
Mast Therapeutics 0.0 $1.3M 4.8M 0.27
Gw Pharmaceuticals Plc ads 0.0 $1.1M 15k 72.13
Chimerix (CMRX) 0.0 $589k 115k 5.11
Acceleron Pharma 0.0 $759k 29k 26.39
Five Prime Therapeutics 0.0 $782k 19k 40.63
Aldeyra Therapeutics (ALDX) 0.0 $595k 142k 4.19
Assembly Biosciences 0.0 $1.3M 250k 5.02
Tenax Therapeutics 0.0 $861k 420k 2.05
Cellectis S A (CLLS) 0.0 $1.4M 50k 27.50
Adaptimmune Therapeutics (ADAP) 0.0 $813k 100k 8.13
Arbutus Biopharma (ABUS) 0.0 $746k 181k 4.13
Pronai Therapeutics 0.0 $1.3M 200k 6.74
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $76k 13k 5.73
Chemocentryx 0.0 $122k 49k 2.49
Foundation Medicine 0.0 $380k 21k 18.19
La Jolla Pharmaceuticl Com Par 0.0 $287k 14k 20.88
Achaogen 0.0 $276k 100k 2.76
Biotime Inc wts oct 1 18 0.0 $12k 20k 0.60
Aptose Biosciences 0.0 $100k 33k 2.99
Ritter Pharmaceuticals 0.0 $452k 400k 1.13
Discovery Laboratories 0.0 $426k 255k 1.67