Baker Bros. Advisors

Baker Bros. Advisors as of Sept. 30, 2016

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 134 positions in its portfolio as reported in the September 2016 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seattle Genetics 21.6 $2.4B 44M 54.01
Incyte Corporation (INCY) 20.1 $2.2B 24M 94.29
Abbvie (ABBV) 8.2 $905M 14M 63.07
ACADIA Pharmaceuticals (ACAD) 7.5 $821M 26M 31.81
Alexion Pharmaceuticals 7.3 $802M 6.5M 122.54
Incyte Corp Ltd conv 4.8 $533M 275M 1.94
Incyte Corp Incy Cvt 144a 0.37 convert 4.5 $492M 259M 1.90
BioMarin Pharmaceutical (BMRN) 4.0 $445M 4.8M 92.52
Genomic Health 3.6 $398M 14M 28.92
Dbv Technologies S A (DBVT) 1.8 $200M 5.5M 36.33
Aquinox Pharmaceuticals 1.3 $141M 11M 13.36
Biomarin Pharmaceutical Inc note 1.875% 4/2 0.9 $101M 22M 4.53
Bellicum Pharma 0.9 $97M 4.9M 19.90
Cerus Corporation (CERS) 0.7 $81M 13M 6.21
Spark Therapeutics 0.7 $79M 1.3M 60.06
Acorda Therapeutics 0.7 $76M 3.7M 20.88
Clovis Oncology Inc note 2.500% 9/1 0.6 $69M 73M 0.95
Amarin Corporation (AMRN) 0.6 $66M 21M 3.19
Exelixis (EXEL) 0.6 $63M 4.9M 12.79
Acorda Therap note 1.75% 6/15 0.6 $63M 77M 0.82
Beigene (BGNE) 0.5 $59M 1.9M 30.81
Invitae (NVTAQ) 0.5 $57M 6.6M 8.76
Heron Therapeutics (HRTX) 0.5 $49M 2.9M 17.23
BioCryst Pharmaceuticals (BCRX) 0.4 $48M 11M 4.41
Neurocrine Biosciences (NBIX) 0.4 $45M 895k 50.64
Advanced Accelerat spon ads each rep 2 ord 0.4 $39M 1.0M 38.08
Versartis 0.2 $26M 2.1M 12.25
Progenics Pharmaceuticals 0.2 $23M 3.7M 6.33
Foamix Pharmaceuticals 0.2 $23M 2.5M 9.26
Array BioPharma 0.2 $22M 3.3M 6.75
Halozyme Therapeutics (HALO) 0.2 $21M 1.7M 12.08
Xencor (XNCR) 0.2 $21M 872k 24.49
Achillion Pharmaceuticals 0.2 $20M 2.5M 8.10
Bluebird Bio (BLUE) 0.2 $20M 294k 67.78
Merus N V (MRUS) 0.2 $19M 1.2M 16.75
Sangamo Biosciences (SGMO) 0.2 $19M 4.1M 4.63
Idera Pharmaceuticals 0.2 $18M 7.0M 2.56
Derma Sciences 0.2 $18M 3.8M 4.67
Aegerion Pharmaceuticals 2% Du cvbond 0.2 $18M 27M 0.66
Intellia Therapeutics (NTLA) 0.2 $18M 1.1M 17.02
Galapagos Nv- (GLPG) 0.1 $17M 260k 64.66
Tg Therapeutics (TGTX) 0.1 $16M 2.0M 7.74
Mirati Therapeutics 0.1 $15M 2.3M 6.61
Ascendis Pharma A S (ASND) 0.1 $15M 746k 20.10
Biomarin Pharmaceutical Inc note 0.750%10/1 0.1 $15M 12M 1.20
Vitae Pharmaceuticals 0.1 $13M 638k 20.92
Arrowhead Pharmaceuticals (ARWR) 0.1 $14M 1.9M 7.35
Alkermes (ALKS) 0.1 $12M 250k 47.03
Agios Pharmaceuticals (AGIO) 0.1 $11M 208k 52.82
Macrogenics (MGNX) 0.1 $11M 364k 29.91
Aerie Pharmaceuticals 0.1 $11M 299k 37.74
Dermira 0.1 $11M 326k 33.82
Zogenix 0.1 $11M 1.0M 11.43
Sage Therapeutics (SAGE) 0.1 $9.6M 208k 46.05
Contrafect 0.1 $10M 4.0M 2.48
Aimmune Therapeutics 0.1 $10M 674k 15.00
Dimension Therapeutics 0.1 $10M 1.3M 7.99
Intra Cellular Therapies (ITCI) 0.1 $9.3M 609k 15.24
ImmunoGen 0.1 $8.1M 3.0M 2.68
Ligand Pharmaceuticals In (LGND) 0.1 $7.5M 73k 102.06
Ultragenyx Pharmaceutical (RARE) 0.1 $7.1M 100k 70.94
Alder Biopharmaceuticals 0.1 $7.1M 217k 32.77
Trillium Therapeutics, Inc. Cmn 0.1 $6.1M 414k 14.79
Inotek Pharmaceuticals 5.75% Cb 08/01/2021-registe bond 0.1 $6.7M 5.0M 1.34
Catalyst Pharmaceutical Partners (CPRX) 0.1 $5.6M 5.1M 1.09
Insmed (INSM) 0.1 $5.8M 400k 14.52
Alcobra 0.1 $5.8M 2.3M 2.47
Proqr Thrapeutics N V shs euro (PRQR) 0.1 $5.7M 861k 6.67
Neuroderm Ltd F 0.1 $5.6M 305k 18.49
Natera (NTRA) 0.1 $5.0M 450k 11.11
Medgenics 0.0 $4.9M 881k 5.57
Akari Therapeutics 0.0 $4.2M 497k 8.51
D Stemline Therapeutics 0.0 $3.6M 334k 10.83
Array Biopharma Inc note 3.000% 6/0 0.0 $3.6M 3.0M 1.19
Trevena 0.0 $3.0M 450k 6.75
Concert Pharmaceuticals I equity 0.0 $3.2M 317k 10.11
Ignyta 0.0 $3.6M 571k 6.29
Adamas Pharmaceuticals 0.0 $2.8M 173k 16.41
Loxo Oncology 0.0 $3.6M 138k 26.18
Minerva Neurosciences 0.0 $3.7M 259k 14.11
Proteon Therapeutics 0.0 $2.8M 299k 9.33
Syros Pharmaceuticals 0.0 $2.8M 205k 13.87
Sunesis Pharmaceuticals Inc Ne 0.0 $3.2M 742k 4.37
Osiris Therapeutics 0.0 $2.5M 499k 4.96
Endocyte 0.0 $2.7M 869k 3.09
Enanta Pharmaceuticals (ENTA) 0.0 $2.0M 75k 26.61
Epizyme 0.0 $2.3M 233k 9.84
Karyopharm Therapeutics (KPTI) 0.0 $2.1M 217k 9.73
Glycomimetics (GLYC) 0.0 $2.7M 381k 7.15
Uniqure Nv (QURE) 0.0 $1.8M 230k 7.65
Mediwound Ltd cmn 0.0 $1.7M 226k 7.70
Scynexis 0.0 $1.8M 468k 3.87
Assembly Biosciences 0.0 $1.8M 250k 7.21
Juno Therapeutics 0.0 $2.4M 80k 30.01
Protalix Biotherapeutics Inc note 4.500% 9/1 0.0 $2.3M 3.4M 0.67
Invivo Therapeutics Hldgs 0.0 $2.7M 400k 6.80
Nabriva Therapeutics 0.0 $2.5M 350k 7.05
Ionis Pharmaceuticals (IONS) 0.0 $2.1M 57k 36.65
Selecta Biosciences (RNAC) 0.0 $2.6M 179k 14.25
Aeglea Biotherapeutics 0.0 $2.6M 404k 6.41
Infinity Pharmaceuticals (INFIQ) 0.0 $905k 580k 1.56
Alnylam Pharmaceuticals (ALNY) 0.0 $769k 11k 67.81
BioDelivery Sciences International 0.0 $567k 210k 2.70
Palatin Technologies 0.0 $1.3M 2.1M 0.63
Mast Therapeutics 0.0 $944k 8.6M 0.11
Chimerix (CMRX) 0.0 $638k 115k 5.54
Acceleron Pharma 0.0 $1.0M 29k 36.19
Ophthotech 0.0 $1.6M 36k 46.12
Five Prime Therapeutics 0.0 $1.0M 19k 52.48
Aldeyra Therapeutics (ALDX) 0.0 $1.1M 142k 7.82
Immune Design 0.0 $1.1M 149k 7.58
Tenax Therapeutics 0.0 $970k 420k 2.31
Affimed Therapeutics B V 0.0 $1.1M 400k 2.78
Dynavax Technologies (DVAX) 0.0 $787k 75k 10.49
Aptose Biosciences 0.0 $910k 404k 2.25
Cellectis S A (CLLS) 0.0 $1.2M 50k 24.08
Abeona Therapeutics 0.0 $610k 102k 6.00
Seres Therapeutics (MCRB) 0.0 $1.5M 125k 12.29
Adaptimmune Therapeutics (ADAP) 0.0 $705k 100k 7.05
Colucid Pharmaceuticals 0.0 $1.2M 30k 38.14
Arbutus Biopharma (ABUS) 0.0 $621k 181k 3.44
Ritter Pharmaceuticals 0.0 $672k 400k 1.68
Myokardia 0.0 $1.6M 100k 16.34
Windtree Therapeutics 0.0 $653k 255k 2.56
Madrigal Pharmaceuticals (MDGL) 0.0 $732k 58k 12.67
Fulgent Genetics (FLGT) 0.0 $1.2M 125k 9.22
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $90k 13k 6.79
Chemocentryx 0.0 $296k 49k 6.03
Cytrx 0.0 $389k 660k 0.59
Foundation Medicine 0.0 $488k 21k 23.36
La Jolla Pharmaceuticl Com Par 0.0 $327k 14k 23.79
Achaogen 0.0 $479k 100k 4.79
Biotime Inc wts oct 1 18 0.0 $17k 20k 0.85
Pronai Therapeutics 0.0 $364k 200k 1.82