Baker Bros. Advisors

Baker Bros. Advisors as of Sept. 30, 2017

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 121 positions in its portfolio as reported in the September 2017 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Incyte Corporation (INCY) 32.4 $4.0B 34M 116.74
Seattle Genetics 20.2 $2.5B 46M 54.41
Alexion Pharmaceuticals 9.7 $1.2B 8.6M 140.29
ACADIA Pharmaceuticals (ACAD) 7.9 $973M 26M 37.67
BioMarin Pharmaceutical (BMRN) 4.5 $550M 5.9M 93.07
Genomic Health 3.6 $442M 14M 32.09
Beigene 3.3 $403M 3.9M 103.46
Dbv Technologies S A 1.9 $234M 5.5M 42.44
Aquinox Pharmaceuticals 1.3 $155M 11M 14.19
Advanced Accelerat spon ads each rep 2 ord 1.2 $152M 2.2M 67.62
Spark Therapeutics 1.0 $123M 1.4M 89.16
Ascendis Pharma A S (ASND) 0.7 $85M 2.3M 36.25
Amarin Corporation (AMRN) 0.6 $79M 23M 3.50
Avexis 0.6 $75M 775k 96.73
BioCryst Pharmaceuticals (BCRX) 0.6 $73M 14M 5.24
Invitae (NVTAQ) 0.6 $68M 7.3M 9.37
Array BioPharma 0.5 $64M 5.2M 12.30
Achaogen 0.5 $62M 3.9M 15.95
Bellicum Pharma 0.5 $58M 5.0M 11.55
Exelixis (EXEL) 0.4 $50M 2.1M 24.23
Heron Therapeutics (HRTX) 0.4 $45M 2.8M 16.15
Novavax Inc note 3.750% 2/0 0.3 $40M 89M 0.45
Neurocrine Biosciences (NBIX) 0.3 $38M 617k 61.28
Bluebird Bio (BLUE) 0.3 $33M 241k 137.35
Sangamo Biosciences (SGMO) 0.3 $32M 2.1M 15.00
Acorda Therap note 1.75% 6/15 0.3 $32M 35M 0.90
Abeona Therapeutics 0.2 $29M 1.7M 17.05
Halozyme Therapeutics (HALO) 0.2 $28M 1.6M 17.37
Cerus Corporation (CERS) 0.2 $27M 9.7M 2.73
Mirati Therapeutics 0.2 $27M 2.3M 11.70
Galapagos Nv- (GLPG) 0.2 $26M 260k 101.75
Intellia Therapeutics (NTLA) 0.2 $26M 1.1M 24.85
Sage Therapeutics (SAGE) 0.2 $25M 406k 62.30
Cymabay Therapeutics 0.2 $24M 3.0M 8.06
Progenics Pharmaceuticals 0.2 $23M 3.2M 7.36
Idera Pharmaceuticals 0.2 $23M 10M 2.23
Merus N V (MRUS) 0.2 $23M 1.2M 19.87
Insmed (INSM) 0.2 $22M 700k 31.21
Neuroderm Ltd F 0.2 $22M 572k 38.90
ImmunoGen 0.2 $21M 2.7M 7.65
Xencor (XNCR) 0.2 $20M 872k 22.92
Aimmune Therapeutics 0.1 $17M 674k 24.79
Ignyta 0.1 $16M 1.3M 12.35
Aerie Pharmaceuticals 0.1 $15M 299k 48.60
Myokardia 0.1 $15M 355k 42.85
Biomarin Pharma Inc convertible/ 0.1 $15M 15M 1.01
Biomarin Pharmaceutical Inc note 0.750%10/1 0.1 $14M 12M 1.11
Foamix Pharmaceuticals 0.1 $14M 2.5M 5.55
Acorda Therapeutics 0.1 $12M 520k 23.65
Catalyst Pharmaceutical Partners (CPRX) 0.1 $13M 5.1M 2.52
Ligand Pharmaceuticals In (LGND) 0.1 $10M 73k 136.16
Newlink Genetics Corporation 0.1 $10M 1.0M 10.18
Intra Cellular Therapies (ITCI) 0.1 $9.6M 609k 15.78
Achillion Pharmaceuticals 0.1 $8.3M 1.9M 4.49
Agios Pharmaceuticals (AGIO) 0.1 $8.6M 129k 66.75
Loxo Oncology 0.1 $8.8M 96k 92.12
Assembly Biosciences 0.1 $8.7M 250k 34.92
Syros Pharmaceuticals 0.1 $8.5M 575k 14.72
Vanda Pharmaceuticals (VNDA) 0.1 $7.6M 424k 17.90
Alkermes (ALKS) 0.1 $7.6M 150k 50.84
D Stemline Therapeutics 0.1 $7.0M 634k 11.10
Gw Pharmaceuticals Plc ads 0.1 $7.6M 75k 101.49
Glycomimetics (GLYC) 0.1 $7.9M 563k 13.99
Contrafect 0.1 $7.9M 7.2M 1.11
Aegerion Pharmaceuticals 2% Du cvbond 0.1 $7.6M 9.5M 0.80
Dimension Therapeutics 0.1 $7.5M 1.3M 6.00
Nabriva Therapeutics 0.1 $7.7M 938k 8.19
Rigel Pharmaceuticals 0.1 $6.4M 2.5M 2.54
Tetraphase Pharmaceuticals 0.1 $6.4M 935k 6.84
Acceleron Pharma 0.1 $6.1M 164k 37.32
Macrogenics (MGNX) 0.1 $6.7M 364k 18.48
Aeglea Biotherapeutics 0.1 $5.6M 1.1M 4.93
Spring Bk Pharmaceuticals In 0.1 $6.3M 373k 16.84
Aevi Genomic 0.1 $5.7M 4.5M 1.26
Epizyme 0.0 $4.4M 233k 19.05
Array Biopharma Inc note 3.000% 6/0 0.0 $5.4M 3.0M 1.80
La Jolla Pharmaceuticl Com Par 0.0 $5.4M 155k 34.78
Voyager Therapeutics (VYGR) 0.0 $4.9M 237k 20.59
Selecta Biosciences 0.0 $5.3M 290k 18.25
Versartis 0.0 $3.5M 1.4M 2.45
Adamas Pharmaceuticals 0.0 $3.7M 173k 21.17
Inotek Pharmaceuticals 5.75% Cb 08/01/2021-registe bond 0.0 $3.9M 5.0M 0.78
Albireo Pharma 0.0 $4.2M 200k 20.95
Tonix Pharmaceuticals Hldg C 0.0 $3.2M 700k 4.56
Anaptysbio Inc Common (ANAB) 0.0 $3.9M 111k 34.95
Clementia 0.0 $4.2M 250k 16.89
Novavax 0.0 $2.3M 2.0M 1.14
Karyopharm Therapeutics (KPTI) 0.0 $2.4M 217k 10.98
Trevena 0.0 $2.4M 950k 2.55
Protalix Biotherapeutics Inc note 4.500% 9/1 0.0 $2.6M 3.4M 0.75
Trillium Therapeutics, Inc. Cmn 0.0 $2.1M 414k 5.15
Natera (NTRA) 0.0 $2.9M 229k 12.89
Akari Therapeutics 0.0 $3.1M 497k 6.14
Madrigal Pharmaceuticals (MDGL) 0.0 $2.6M 58k 44.98
Ra Pharmaceuticals 0.0 $2.6M 178k 14.60
Argenx Se (ARGX) 0.0 $2.3M 100k 22.61
Ovid Therapeutics (OVID) 0.0 $2.9M 333k 8.57
Krystal Biotech (KRYS) 0.0 $2.0M 200k 9.97
Infinity Pharmaceuticals (INFIQ) 0.0 $772k 580k 1.33
BioDelivery Sciences International 0.0 $620k 210k 2.95
Five Prime Therapeutics 0.0 $787k 19k 40.89
Mediwound Ltd cmn 0.0 $1.2M 226k 5.35
Immune Design 0.0 $1.5M 149k 10.35
Affimed Therapeutics B V 0.0 $900k 400k 2.25
Dynavax Technologies (DVAX) 0.0 $1.6M 75k 21.51
Cellectis S A (CLLS) 0.0 $1.4M 50k 28.46
Adaptimmune Therapeutics (ADAP) 0.0 $819k 100k 8.19
Arbutus Biopharma (ABUS) 0.0 $1.1M 181k 6.20
Ritter Pharmaceuticals 0.0 $980k 2.8M 0.35
Sunesis Pharmaceuticals Inc Ne 0.0 $1.4M 742k 1.94
Jounce Therapeutics 0.0 $1.6M 100k 15.58
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $98k 13k 7.39
Chemocentryx 0.0 $364k 49k 7.42
T2 Biosystems 0.0 $420k 100k 4.20
Tenax Therapeutics 0.0 $125k 348k 0.36
Proteon Therapeutics 0.0 $597k 299k 2.00
Biotime Inc wts oct 1 18 0.0 $4.0k 20k 0.20
Biopharmx 0.0 $174k 599k 0.29
Invivo Therapeutics Hldgs 0.0 $580k 400k 1.45
Fulgent Genetics (FLGT) 0.0 $599k 125k 4.79
Molecular Templates 0.0 $505k 72k 6.97