Baker Bros. Advisors as of Dec. 31, 2017
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 123 positions in its portfolio as reported in the December 2017 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Incyte Corporation (INCY) | 28.1 | $3.2B | 34M | 94.71 | |
| Seattle Genetics | 21.2 | $2.4B | 46M | 53.50 | |
| Alexion Pharmaceuticals | 8.9 | $1.0B | 8.6M | 119.59 | |
| ACADIA Pharmaceuticals (ACAD) | 7.1 | $820M | 27M | 30.11 | |
| BioMarin Pharmaceutical (BMRN) | 5.9 | $676M | 7.6M | 89.17 | |
| Genomic Health | 4.1 | $471M | 14M | 34.20 | |
| Beigene (BGNE) | 3.3 | $376M | 3.8M | 97.72 | |
| Dbv Technologies S A | 1.2 | $136M | 5.5M | 24.60 | |
| Aquinox Pharmaceuticals | 1.1 | $129M | 11M | 11.76 | |
| Ascendis Pharma A S (ASND) | 0.9 | $105M | 2.6M | 40.06 | |
| Ablynx Nv | 0.9 | $104M | 4.2M | 24.99 | |
| Sage Therapeutics (SAGE) | 0.9 | $102M | 617k | 164.71 | |
| Amarin Corporation (AMRN) | 0.8 | $91M | 23M | 4.01 | |
| Avexis | 0.7 | $86M | 775k | 110.67 | |
| Neurocrine Biosciences (NBIX) | 0.7 | $78M | 1.0M | 77.59 | |
| Array BioPharma | 0.6 | $72M | 5.7M | 12.80 | |
| Spark Therapeutics | 0.6 | $71M | 1.4M | 51.42 | |
| BioCryst Pharmaceuticals (BCRX) | 0.6 | $69M | 14M | 4.91 | |
| Erytech Pharma Sa | 0.6 | $68M | 3.1M | 22.02 | |
| Invitae (NVTAQ) | 0.6 | $66M | 7.3M | 9.08 | |
| Argenx Se (ARGX) | 0.5 | $61M | 962k | 63.14 | |
| Rhythm Pharmaceuticals (RYTM) | 0.5 | $60M | 2.0M | 29.06 | |
| Madrigal Pharmaceuticals (MDGL) | 0.5 | $57M | 616k | 91.79 | |
| Heron Therapeutics (HRTX) | 0.5 | $55M | 3.1M | 18.10 | |
| Exelixis (EXEL) | 0.4 | $46M | 1.5M | 30.40 | |
| Mirati Therapeutics | 0.4 | $47M | 2.5M | 18.25 | |
| Bellicum Pharma | 0.4 | $42M | 5.0M | 8.41 | |
| Novavax Inc note 3.750% 2/0 | 0.3 | $41M | 89M | 0.46 | |
| Idera Pharmaceuticals | 0.3 | $39M | 18M | 2.11 | |
| Ignyta | 0.3 | $37M | 1.4M | 26.70 | |
| Bluebird Bio (BLUE) | 0.3 | $36M | 200k | 178.10 | |
| Sangamo Biosciences (SGMO) | 0.3 | $35M | 2.1M | 16.40 | |
| Cerus Corporation (CERS) | 0.3 | $33M | 9.7M | 3.38 | |
| Halozyme Therapeutics (HALO) | 0.3 | $32M | 1.6M | 20.26 | |
| Abeona Therapeutics | 0.3 | $32M | 2.0M | 15.85 | |
| Acorda Therap note 1.75% 6/15 | 0.3 | $30M | 35M | 0.85 | |
| Gw Pharmaceuticals Plc ads | 0.2 | $29M | 222k | 132.01 | |
| Cymabay Therapeutics | 0.2 | $28M | 3.0M | 9.20 | |
| Aimmune Therapeutics | 0.2 | $26M | 674k | 37.82 | |
| Galapagos Nv- (GLPG) | 0.2 | $24M | 260k | 93.76 | |
| Catalyst Pharmaceutical Partners (CPRX) | 0.2 | $23M | 5.9M | 3.91 | |
| Merus N V (MRUS) | 0.2 | $23M | 1.2M | 19.40 | |
| Insmed (INSM) | 0.2 | $22M | 700k | 31.18 | |
| Intellia Therapeutics (NTLA) | 0.2 | $22M | 1.1M | 19.22 | |
| Xencor (XNCR) | 0.2 | $19M | 872k | 21.92 | |
| Progenics Pharmaceuticals | 0.2 | $19M | 3.2M | 5.95 | |
| Aerie Pharmaceuticals | 0.2 | $18M | 299k | 59.75 | |
| Anaptysbio Inc Common (ANAB) | 0.2 | $18M | 181k | 100.72 | |
| ImmunoGen | 0.1 | $16M | 2.6M | 6.41 | |
| Assembly Biosciences | 0.1 | $15M | 323k | 45.25 | |
| Foamix Pharmaceuticals | 0.1 | $15M | 2.5M | 6.01 | |
| Myokardia | 0.1 | $15M | 355k | 42.10 | |
| Biomarin Pharma Inc convertible/ | 0.1 | $15M | 15M | 1.00 | |
| Biomarin Pharmaceutical Inc note 0.750%10/1 | 0.1 | $13M | 12M | 1.08 | |
| Nektar Therapeutics (NKTR) | 0.1 | $10M | 172k | 59.72 | |
| Ligand Pharmaceuticals In (LGND) | 0.1 | $10M | 73k | 136.93 | |
| D Stemline Therapeutics | 0.1 | $9.9M | 634k | 15.60 | |
| Rigel Pharmaceuticals | 0.1 | $9.8M | 2.5M | 3.88 | |
| Glycomimetics (GLYC) | 0.1 | $9.5M | 563k | 16.79 | |
| Uniqure Nv (QURE) | 0.1 | $9.5M | 483k | 19.59 | |
| Intra Cellular Therapies (ITCI) | 0.1 | $8.8M | 609k | 14.48 | |
| Achillion Pharmaceuticals | 0.1 | $8.2M | 2.9M | 2.88 | |
| Alkermes (ALKS) | 0.1 | $8.2M | 150k | 54.73 | |
| Newlink Genetics Corporation | 0.1 | $8.2M | 1.0M | 8.11 | |
| Aegerion Pharmaceuticals 2% Du cvbond | 0.1 | $7.5M | 9.5M | 0.79 | |
| Vanda Pharmaceuticals (VNDA) | 0.1 | $6.4M | 424k | 15.20 | |
| Acceleron Pharma | 0.1 | $7.0M | 164k | 42.44 | |
| Agios Pharmaceuticals (AGIO) | 0.1 | $7.4M | 129k | 57.17 | |
| Macrogenics (MGNX) | 0.1 | $6.9M | 364k | 19.00 | |
| Contrafect | 0.1 | $7.2M | 7.2M | 1.01 | |
| Tetraphase Pharmaceuticals | 0.1 | $5.9M | 935k | 6.30 | |
| Adamas Pharmaceuticals | 0.1 | $5.9M | 173k | 33.89 | |
| Aeglea Biotherapeutics | 0.1 | $6.2M | 1.1M | 5.41 | |
| Syros Pharmaceuticals | 0.1 | $5.6M | 575k | 9.73 | |
| Nabriva Therapeutics | 0.1 | $5.6M | 938k | 5.98 | |
| Acorda Therapeutics | 0.0 | $4.4M | 206k | 21.45 | |
| Endocyte | 0.0 | $4.7M | 1.1M | 4.28 | |
| La Jolla Pharmaceuticl Com Par | 0.0 | $5.0M | 155k | 32.18 | |
| Corbus Pharmaceuticals Hldgs | 0.0 | $4.7M | 661k | 7.10 | |
| Advanced Accelerat spon ads each rep 2 ord | 0.0 | $4.5M | 55k | 81.61 | |
| Spring Bk Pharmaceuticals In | 0.0 | $5.0M | 373k | 13.44 | |
| Albireo Pharma | 0.0 | $5.1M | 200k | 25.60 | |
| Aevi Genomic | 0.0 | $4.9M | 4.1M | 1.20 | |
| Clementia | 0.0 | $4.7M | 250k | 18.98 | |
| Inflarx Nv (IFRX) | 0.0 | $4.2M | 200k | 20.95 | |
| Epizyme | 0.0 | $2.9M | 233k | 12.55 | |
| Versartis | 0.0 | $3.1M | 1.4M | 2.20 | |
| Trillium Therapeutics, Inc. Cmn | 0.0 | $3.0M | 409k | 7.25 | |
| Akari Therapeutics | 0.0 | $3.0M | 697k | 4.33 | |
| Inotek Pharmaceuticals 5.75% Cb 08/01/2021-registe bond | 0.0 | $4.0M | 5.0M | 0.80 | |
| Ovid Therapeutics (OVID) | 0.0 | $3.3M | 333k | 9.87 | |
| Novavax | 0.0 | $2.5M | 2.0M | 1.24 | |
| Karyopharm Therapeutics (KPTI) | 0.0 | $2.1M | 217k | 9.60 | |
| Protalix Biotherapeutics Inc note 4.500% 9/1 | 0.0 | $2.6M | 3.4M | 0.75 | |
| Natera (NTRA) | 0.0 | $2.1M | 229k | 8.99 | |
| Selecta Biosciences | 0.0 | $2.8M | 284k | 9.81 | |
| Sunesis Pharmaceuticals Inc Ne | 0.0 | $2.7M | 742k | 3.69 | |
| Tonix Pharmaceuticals Hldg C | 0.0 | $2.4M | 700k | 3.45 | |
| Krystal Biotech (KRYS) | 0.0 | $2.1M | 200k | 10.52 | |
| Infinity Pharmaceuticals (INFIQ) | 0.0 | $1.2M | 580k | 2.03 | |
| BioDelivery Sciences International | 0.0 | $620k | 210k | 2.95 | |
| Achaogen | 0.0 | $1.3M | 123k | 10.74 | |
| Trevena | 0.0 | $1.5M | 950k | 1.60 | |
| Mediwound Ltd cmn | 0.0 | $1.0M | 226k | 4.45 | |
| Immune Design | 0.0 | $581k | 149k | 3.90 | |
| Dynavax Technologies (DVAX) | 0.0 | $1.4M | 75k | 18.71 | |
| Cellectis S A (CLLS) | 0.0 | $1.5M | 50k | 29.16 | |
| Adaptimmune Therapeutics (ADAP) | 0.0 | $668k | 100k | 6.68 | |
| Arbutus Biopharma (ABUS) | 0.0 | $912k | 181k | 5.05 | |
| Ritter Pharmaceuticals | 0.0 | $924k | 2.8M | 0.33 | |
| Ra Pharmaceuticals | 0.0 | $1.5M | 178k | 8.50 | |
| Jounce Therapeutics | 0.0 | $1.3M | 100k | 12.75 | |
| Molecular Templates | 0.0 | $726k | 72k | 10.03 | |
| Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) | 0.0 | $92k | 13k | 6.94 | |
| Chemocentryx | 0.0 | $292k | 49k | 5.95 | |
| Five Prime Therapeutics | 0.0 | $422k | 19k | 21.93 | |
| T2 Biosystems | 0.0 | $412k | 100k | 4.12 | |
| Tenax Therapeutics | 0.0 | $171k | 348k | 0.49 | |
| Affimed Therapeutics B V | 0.0 | $520k | 400k | 1.30 | |
| Proteon Therapeutics | 0.0 | $567k | 299k | 1.90 | |
| Biotime Inc wts oct 1 18 | 0.0 | $2.0k | 20k | 0.10 | |
| Invivo Therapeutics Hldgs | 0.0 | $255k | 331k | 0.77 | |
| Fulgent Genetics (FLGT) | 0.0 | $548k | 125k | 4.38 |
