Baker Bros. Advisors

Baker Bros. Advisors as of March 31, 2017

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 119 positions in its portfolio as reported in the March 2017 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Incyte Corporation (INCY) 37.3 $4.6B 34M 133.67
Seattle Genetics 23.5 $2.9B 46M 62.86
ACADIA Pharmaceuticals (ACAD) 7.3 $888M 26M 34.38
Alexion Pharmaceuticals 6.5 $793M 6.5M 121.24
Genomic Health 3.5 $434M 14M 31.49
BioMarin Pharmaceutical (BMRN) 3.5 $422M 4.8M 87.78
Dbv Technologies S A 1.6 $194M 5.5M 35.22
Aquinox Pharmaceuticals 1.5 $183M 11M 16.69
Beigene 1.1 $135M 3.7M 36.61
Achaogen 0.9 $116M 4.6M 25.23
BioCryst Pharmaceuticals (BCRX) 0.8 $98M 12M 8.40
Biomarin Pharmaceutical Inc note 1.875% 4/2 0.8 $96M 22M 4.29
Advanced Accelerat spon ads each rep 2 ord 0.7 $89M 2.2M 39.86
Invitae (NVTAQ) 0.7 $81M 7.3M 11.06
Amarin Corporation (AMRN) 0.6 $73M 23M 3.20
Spark Therapeutics 0.6 $70M 1.3M 53.34
Acorda Therapeutics 0.6 $69M 3.3M 21.00
Bellicum Pharma 0.5 $62M 5.0M 12.34
Cerus Corporation (CERS) 0.5 $58M 13M 4.45
Exelixis (EXEL) 0.5 $56M 2.6M 21.67
Novavax Inc note 3.750% 2/0 0.4 $49M 109M 0.45
Heron Therapeutics (HRTX) 0.3 $42M 2.8M 15.00
Neurocrine Biosciences (NBIX) 0.3 $39M 895k 43.30
Ascendis Pharma A S (ASND) 0.3 $38M 1.4M 28.00
Avexis 0.3 $38M 500k 76.03
Versartis 0.3 $36M 1.7M 21.35
Bluebird Bio (BLUE) 0.3 $32M 351k 90.90
Progenics Pharmaceuticals 0.2 $30M 3.2M 9.44
Acorda Therap note 1.75% 6/15 0.2 $30M 35M 0.85
Merus N V (MRUS) 0.2 $28M 1.2M 24.39
Idera Pharmaceuticals 0.2 $25M 10M 2.47
Sangamo Biosciences (SGMO) 0.2 $24M 4.5M 5.20
Galapagos Nv- (GLPG) 0.2 $22M 260k 86.19
Xencor (XNCR) 0.2 $21M 872k 23.92
Halozyme Therapeutics (HALO) 0.1 $18M 1.4M 12.96
Array BioPharma 0.1 $14M 1.6M 8.94
Sage Therapeutics (SAGE) 0.1 $15M 208k 71.07
Neuroderm Ltd F 0.1 $15M 572k 26.55
Dermira 0.1 $14M 415k 34.11
Aimmune Therapeutics 0.1 $15M 674k 21.73
Intellia Therapeutics (NTLA) 0.1 $15M 1.1M 14.09
Aerie Pharmaceuticals 0.1 $14M 299k 45.35
Biomarin Pharmaceutical Inc note 0.750%10/1 0.1 $14M 12M 1.13
Aegerion Pharmaceuticals 2% Du cvbond 0.1 $13M 17M 0.80
ImmunoGen 0.1 $12M 3.0M 3.87
Mirati Therapeutics 0.1 $12M 2.3M 5.20
Foamix Pharmaceuticals 0.1 $12M 2.5M 4.95
La Jolla Pharmaceuticl Com Par 0.1 $11M 379k 29.85
Catalyst Pharmaceutical Partners (CPRX) 0.1 $9.9M 5.1M 1.95
Intra Cellular Therapies (ITCI) 0.1 $9.9M 609k 16.25
Rigel Pharmaceuticals 0.1 $8.3M 2.5M 3.31
Alkermes (ALKS) 0.1 $8.8M 150k 58.50
Abeona Therapeutics 0.1 $8.4M 1.7M 5.00
Achillion Pharmaceuticals 0.1 $7.8M 1.9M 4.21
Ligand Pharmaceuticals In (LGND) 0.1 $7.8M 73k 105.84
Insmed (INSM) 0.1 $7.0M 400k 17.51
Agios Pharmaceuticals (AGIO) 0.1 $7.5M 129k 58.40
Macrogenics (MGNX) 0.1 $6.8M 364k 18.60
Contrafect 0.1 $7.3M 4.0M 1.80
Loxo Oncology 0.1 $5.8M 138k 42.08
Cymabay Therapeutics 0.1 $6.1M 1.4M 4.30
Assembly Biosciences 0.1 $6.4M 250k 25.49
Akari Therapeutics 0.1 $5.5M 497k 11.07
Biogen Idec (BIIB) 0.0 $4.5M 17k 273.39
D Stemline Therapeutics 0.0 $5.4M 634k 8.55
Ignyta 0.0 $4.9M 571k 8.60
Alder Biopharmaceuticals 0.0 $4.5M 217k 20.80
Epizyme 0.0 $4.0M 233k 17.15
Array Biopharma Inc note 3.000% 6/0 0.0 $4.3M 3.0M 1.42
Ultragenyx Pharmaceutical (RARE) 0.0 $3.4M 50k 67.78
Trevena 0.0 $3.1M 857k 3.67
Zogenix 0.0 $4.1M 382k 10.85
Nabriva Therapeutics 0.0 $4.2M 350k 12.00
Syros Pharmaceuticals 0.0 $3.3M 205k 15.93
Ra Pharmaceuticals 0.0 $3.8M 178k 21.29
Anaptysbio Inc Common (ANAB) 0.0 $4.2M 150k 27.75
Infinity Pharmaceuticals (INFIQ) 0.0 $1.9M 580k 3.23
Karyopharm Therapeutics (KPTI) 0.0 $2.8M 217k 12.84
Glycomimetics (GLYC) 0.0 $2.1M 381k 5.43
Adamas Pharmaceuticals 0.0 $3.0M 173k 17.50
Protalix Biotherapeutics Inc note 4.500% 9/1 0.0 $2.5M 3.4M 0.74
Trillium Therapeutics, Inc. Cmn 0.0 $2.5M 414k 6.15
Natera (NTRA) 0.0 $2.0M 229k 8.87
Dimension Therapeutics 0.0 $2.2M 1.3M 1.75
Selecta Biosciences 0.0 $2.5M 176k 14.32
Spring Bk Pharmaceuticals In 0.0 $2.0M 219k 8.90
Sunesis Pharmaceuticals Inc Ne 0.0 $3.0M 742k 4.10
Inotek Pharmaceuticals 5.75% Cb 08/01/2021-registe bond 0.0 $3.0M 5.0M 0.60
Aevi Genomic 0.0 $3.0M 1.6M 1.86
Tonix Pharmaceuticals Hldg C 0.0 $2.1M 450k 4.67
Jounce Therapeutics 0.0 $2.2M 100k 21.99
Palatin Technologies 0.0 $677k 2.1M 0.33
Chimerix (CMRX) 0.0 $735k 115k 6.38
Acceleron Pharma 0.0 $761k 29k 26.46
Five Prime Therapeutics 0.0 $696k 19k 36.16
Mediwound Ltd cmn 0.0 $1.5M 226k 6.60
Immune Design 0.0 $1.0M 149k 6.80
Affimed Therapeutics B V 0.0 $920k 400k 2.30
Juno Therapeutics 0.0 $1.1M 50k 22.20
Cellectis S A (CLLS) 0.0 $1.2M 50k 24.00
Invivo Therapeutics Hldgs 0.0 $1.6M 400k 4.05
Seres Therapeutics (MCRB) 0.0 $1.4M 125k 11.27
Corbus Pharmaceuticals Hldgs 0.0 $1.1M 130k 8.25
Myokardia 0.0 $1.3M 100k 13.15
Aeglea Biotherapeutics 0.0 $1.4M 190k 7.45
Madrigal Pharmaceuticals (MDGL) 0.0 $890k 58k 15.41
Fulgent Genetics (FLGT) 0.0 $1.4M 125k 10.92
BioDelivery Sciences International 0.0 $399k 210k 1.90
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $83k 13k 6.26
Chemocentryx 0.0 $357k 49k 7.28
Dynavax Technologies (DVAX) 0.0 $446k 75k 5.95
Proteon Therapeutics 0.0 $523k 299k 1.75
Biotime Inc wts oct 1 18 0.0 $12k 20k 0.60
Biopharmx 0.0 $192k 377k 0.51
Adaptimmune Therapeutics (ADAP) 0.0 $551k 100k 5.51
Arbutus Biopharma (ABUS) 0.0 $587k 181k 3.25
Ritter Pharmaceuticals 0.0 $568k 400k 1.42
Windtree Therapeutics 0.0 $291k 255k 1.14
Bioverativ Inc Com equity 0.0 $449k 8.2k 54.43