Perceptive Advisors as of Dec. 31, 2025
Portfolio Holdings for Perceptive Advisors
Perceptive Advisors holds 116 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Praxis Precision Medicines I Com New (PRAX) | 10.5 | $588M | 2.0M | 294.74 | |
| Celcuity (CELC) | 5.6 | $315M | 3.2M | 99.74 | |
| Rhythm Pharmaceuticals (RYTM) | 4.9 | $273M | 2.5M | 107.04 | |
| Ascendis Pharma A/s Sponsored Adr (ASND) | 4.1 | $231M | 1.1M | 213.24 | |
| Apogee Therapeutics (APGE) | 3.1 | $176M | 2.3M | 75.48 | |
| Roivant Sciences SHS (ROIV) | 3.1 | $173M | 8.0M | 21.70 | |
| Nuvalent Inc-a (NUVL) | 3.0 | $168M | 1.7M | 100.59 | |
| Travere Therapeutics (TVTX) | 2.9 | $164M | 4.3M | 38.21 | |
| Spdr Series Trust State Street Spd Put Option (XBI) | 2.4 | $134M | 1.1M | 121.93 | |
| EXACT Sciences Corporation | 2.2 | $122M | 1.2M | 101.56 | |
| Protagonist Therapeutics (PTGX) | 2.1 | $118M | 1.4M | 87.34 | |
| Inhibrx Biosciences (INBX) | 2.0 | $115M | 1.5M | 79.00 | |
| Edgewise Therapeutics (EWTX) | 2.0 | $111M | 4.5M | 24.82 | |
| Immatics SHS (IMTX) | 1.9 | $109M | 10M | 10.50 | |
| Spyre Therapeutics Com New (SYRE) | 1.8 | $101M | 3.1M | 32.76 | |
| Amylyx Pharmaceuticals (AMLX) | 1.8 | $100M | 8.3M | 12.08 | |
| Arcellx Common Stock (ACLX) | 1.7 | $96M | 1.5M | 65.20 | |
| Miragen Therapeutics (VRDN) | 1.7 | $95M | 3.0M | 31.12 | |
| Boston Scientific Corporation (BSX) | 1.7 | $93M | 979k | 95.35 | |
| Amicus Therapeutics (FOLD) | 1.6 | $91M | 6.4M | 14.24 | |
| Zymeworks Del (ZYME) | 1.5 | $86M | 3.3M | 26.33 | |
| Astria Therapeutics | 1.5 | $85M | 6.5M | 13.09 | |
| Meiragtx Holdings (MGTX) | 1.5 | $82M | 10M | 7.95 | |
| CryoLife (AORT) | 1.4 | $79M | 1.7M | 45.61 | |
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 1.3 | $73M | 2.9M | 25.01 | |
| Dyne Therapeutics (DYN) | 1.2 | $68M | 3.5M | 19.56 | |
| Nurix Therapeutics (NRIX) | 1.2 | $68M | 3.6M | 18.97 | |
| Solid Biosciences Com New (SLDB) | 1.2 | $67M | 12M | 5.64 | |
| Belite Bio Sponsored Ads (BLTE) | 1.2 | $66M | 414k | 159.96 | |
| Abivax Sa Sponsored Ads (ABVX) | 1.1 | $62M | 458k | 134.85 | |
| Adagio Therapeutics (IVVD) | 1.0 | $54M | 22M | 2.47 | |
| Engene Holdings (ENGN) | 0.9 | $53M | 5.9M | 9.03 | |
| Repligen Corporation (RGEN) | 0.9 | $52M | 316k | 163.86 | |
| Immunovant (IMVT) | 0.9 | $51M | 2.0M | 25.42 | |
| Intuitive Surgical Com New (ISRG) | 0.9 | $50M | 88k | 566.36 | |
| Sionna Therapeutics (SION) | 0.9 | $49M | 1.2M | 41.14 | |
| Neurocrine Biosciences (NBIX) | 0.8 | $47M | 331k | 141.83 | |
| Danaher Corporation (DHR) | 0.8 | $46M | 200k | 228.92 | |
| Oruka Therapeutics (ORKA) | 0.8 | $45M | 1.5M | 30.31 | |
| Cytomx Therapeutics (CTMX) | 0.7 | $41M | 9.7M | 4.26 | |
| Omada Health (OMDA) | 0.7 | $38M | 2.4M | 15.78 | |
| Cidara Therapeutics Com New (CDTX) | 0.7 | $37M | 165k | 220.89 | |
| Disc Medicine (IRON) | 0.6 | $36M | 451k | 79.41 | |
| Bright Minds Biosciences Com New (DRUG) | 0.6 | $35M | 449k | 78.04 | |
| Penumbra (PEN) | 0.6 | $34M | 111k | 310.91 | |
| Alto Neuroscience Com Shs (ANRO) | 0.6 | $32M | 1.8M | 17.80 | |
| Caris Life Sciences (CAI) | 0.5 | $31M | 1.1M | 26.98 | |
| Jazz Pharmaceuticals Shs Usd (JAZZ) | 0.5 | $29M | 170k | 170.00 | |
| Palisade Bio (PALI) | 0.5 | $28M | 12M | 2.35 | |
| Rapt Therapeutics Com New (RAPT) | 0.5 | $28M | 826k | 33.87 | |
| Palvella Therapeutics Inc Ne (PVLA) | 0.5 | $28M | 266k | 104.67 | |
| Axsome Therapeutics (AXSM) | 0.5 | $27M | 149k | 182.64 | |
| Axogen (AXGN) | 0.5 | $26M | 784k | 32.73 | |
| X4 Pharmaceuticals Com New (XFOR) | 0.5 | $25M | 6.3M | 4.00 | |
| BioCryst Pharmaceuticals (BCRX) | 0.4 | $25M | 3.2M | 7.80 | |
| Nautilus Biotechnology (NAUT) | 0.4 | $25M | 13M | 1.95 | |
| Kodiak Sciences (KOD) | 0.4 | $24M | 849k | 27.96 | |
| Biogen Idec (BIIB) | 0.4 | $22M | 124k | 175.99 | |
| Aldeyra Therapeutics (ALDX) | 0.4 | $22M | 4.2M | 5.18 | |
| Health Sciences Acq Corp 2 (OBIO) | 0.4 | $21M | 5.1M | 4.15 | |
| Mirum Pharmaceuticals (MIRM) | 0.4 | $21M | 260k | 78.99 | |
| Rapport Therapeutics (RAPP) | 0.4 | $20M | 674k | 30.34 | |
| Grail (GRAL) | 0.4 | $20M | 237k | 85.59 | |
| Irhythm Technologies (IRTC) | 0.3 | $19M | 108k | 177.44 | |
| Beta Bionics (BBNX) | 0.3 | $18M | 603k | 30.47 | |
| CVS Caremark Corporation (CVS) | 0.3 | $18M | 220k | 79.36 | |
| Contineum Therapeutics Cl A (CTNM) | 0.3 | $17M | 1.5M | 11.43 | |
| Guardant Health (GH) | 0.3 | $16M | 160k | 102.14 | |
| Adma Biologics (ADMA) | 0.3 | $16M | 884k | 18.24 | |
| Relay Therapeutics (RLAY) | 0.3 | $16M | 1.9M | 8.46 | |
| Glaukos (GKOS) | 0.3 | $16M | 140k | 112.91 | |
| Dex (DXCM) | 0.3 | $15M | 226k | 66.37 | |
| Savara (SVRA) | 0.3 | $15M | 2.4M | 6.03 | |
| Celcuity Note 2.750% 8/0 (Principal) | 0.3 | $14M | 6.5M | 2.17 | |
| Athira Pharma (LONA) | 0.3 | $14M | 1.9M | 7.57 | |
| Septerna (SEPN) | 0.2 | $12M | 433k | 27.88 | |
| Inhibikase Therapeutics Com New (IKT) | 0.2 | $11M | 5.4M | 2.05 | |
| Adagio Med Hldgs (ADGM) | 0.2 | $10M | 9.9M | 1.04 | |
| Oculis Holding Ordinary Shares (OCS) | 0.2 | $9.9M | 494k | 19.97 | |
| Gossamer Bio (GOSS) | 0.2 | $9.7M | 3.1M | 3.10 | |
| Maplight Therapeutics (MPLT) | 0.2 | $9.7M | 550k | 17.57 | |
| Xenon Pharmaceuticals (XENE) | 0.2 | $9.0M | 201k | 44.82 | |
| Ocuphire Pharma (IRD) | 0.2 | $8.7M | 4.3M | 2.01 | |
| Anteris Technologies Global (AVR) | 0.1 | $8.4M | 1.7M | 4.99 | |
| Kestra Med Technologies SHS (KMTS) | 0.1 | $7.6M | 285k | 26.52 | |
| Capricor Therapeutics Com New Call Option (CAPR) | 0.1 | $7.0M | 242k | 28.86 | |
| Billiontoone Cl A (BLLN) | 0.1 | $6.0M | 73k | 81.84 | |
| Biohaven Call Option (BHVN) | 0.1 | $5.6M | 500k | 11.29 | |
| Kymera Therapeutics (KYMR) | 0.1 | $5.4M | 70k | 77.81 | |
| Pepgen (PEPG) | 0.1 | $5.4M | 830k | 6.51 | |
| Crescent Biopharma (CBIO) | 0.1 | $5.4M | 454k | 11.86 | |
| Tenax Therapeutics Com New (TENX) | 0.1 | $5.4M | 439k | 12.19 | |
| Corvus Pharmaceuticals (CRVS) | 0.1 | $5.3M | 692k | 7.70 | |
| Tectonic Therapeutic Call Option (TECX) | 0.1 | $5.2M | 250k | 20.86 | |
| Aquestive Therapeutics (AQST) | 0.1 | $4.8M | 747k | 6.46 | |
| Tango Therapeutics (TNGX) | 0.1 | $4.5M | 513k | 8.86 | |
| Krystal Biotech (KRYS) | 0.1 | $4.3M | 18k | 246.54 | |
| Cogent Biosciences (COGT) | 0.1 | $4.3M | 121k | 35.52 | |
| Olema Pharmaceuticals (OLMA) | 0.1 | $4.1M | 166k | 25.00 | |
| Schrodinger (SDGR) | 0.1 | $3.6M | 202k | 17.88 | |
| Outset Med Com New (OM) | 0.1 | $3.1M | 833k | 3.71 | |
| Sab Biotherapeutics Com New (SABS) | 0.1 | $3.0M | 803k | 3.74 | |
| Avalo Therapeutics Com New (AVTX) | 0.0 | $2.5M | 140k | 18.16 | |
| Connect Biopharma Hldgs SHS (CNTB) | 0.0 | $2.2M | 793k | 2.82 | |
| Immix Biopharma (IMMX) | 0.0 | $1.8M | 339k | 5.23 | |
| Lexeo Therapeutics (LXEO) | 0.0 | $1.4M | 140k | 9.93 | |
| Cumberland Pharmaceuticals (CPIX) | 0.0 | $1.4M | 341k | 3.98 | |
| Medline Com Cl A (MDLN) | 0.0 | $1.2M | 28k | 42.00 | |
| Palatin Technologies Com New (PTN) | 0.0 | $1.1M | 70k | 15.38 | |
| Lenz Therapeutics (LENZ) | 0.0 | $800k | 50k | 16.00 | |
| Biodesix (BDSX) | 0.0 | $739k | 109k | 6.80 | |
| Envveno Medical (NVNO) | 0.0 | $564k | 1.8M | 0.32 | |
| Iovance Biotherapeutics (IOVA) | 0.0 | $417k | 153k | 2.73 | |
| Revolution Medicines *w Exp 12/17/202 (RVMDW) | 0.0 | $235k | 250k | 0.94 | |
| Ensysce Biosciences Com New (ENSC) | 0.0 | $80k | 87k | 0.92 | |
| Surrozen *w Exp 08/01/203 (SRZNW) | 0.0 | $3.3k | 167k | 0.02 |
