Siren
Latest statistics and disclosures from Siren's latest quarterly 13F-HR filing:
- Central Index Key (CIK): 0002005245
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Portfolio Holdings for Siren
Siren holds 110 positions in its portfolio as reported in the September 2024 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Kymera Therapeutics (KYMR) | 7.0 | $141M | 3.0M | 47.33 |
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| Beigene Sponsored Adr (BGNE) | 6.3 | $127M | 563k | 224.51 |
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| Scholar Rock Hldg Corp (SRRK) | 4.5 | $90M | 11M | 8.01 |
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| Bicara Therapeutics | 3.9 | $78M | 3.1M | 25.47 |
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| Argenx SE Sponsored Adr (ARGX) | 3.9 | $78M | 144k | 542.08 |
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| Crinetics Pharmaceuticals In (CRNX) | 3.3 | $67M | 1.3M | 51.10 |
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| Avidity Biosciences Ord (RNA) | 3.3 | $66M | 1.4M | 45.93 |
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| Apellis Pharmaceuticals (APLS) | 3.1 | $63M | 2.2M | 28.84 |
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| Lexicon Pharmaceuticals Com New (LXRX) | 3.1 | $61M | 39M | 1.57 |
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| Igm Biosciences (IGMS) | 2.8 | $55M | 3.3M | 16.54 |
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| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 2.6 | $52M | 3.3M | 15.99 |
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| Ascendis Pharma A/S Sponsored Adr (ASND) | 2.6 | $52M | 348k | 149.31 |
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| Silence Therapeutics Ads (SLN) | 2.6 | $52M | 2.8M | 18.18 |
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| Arrowhead Pharmaceuticals (ARWR) | 2.4 | $48M | 2.5M | 19.37 |
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| WAVE Life Sciences SHS (WVE) | 2.3 | $47M | 5.7M | 8.20 |
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| Springworks Therapeutics (SWTX) | 2.2 | $44M | 1.4M | 32.04 |
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| Dyne Therapeutics (DYN) | 2.0 | $41M | 1.1M | 35.92 |
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| Vera Therapeutics Cl A (VERA) | 1.9 | $37M | 838k | 44.20 |
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| Neumora Therapeutics (NMRA) | 1.7 | $34M | 2.6M | 13.21 |
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| Vaxcyte (PCVX) | 1.7 | $34M | 300k | 114.27 |
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| Revolution Medicines (RVMD) | 1.7 | $34M | 754k | 45.35 |
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| Merus N V (MRUS) | 1.7 | $34M | 682k | 49.96 |
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| Taboola.com Ord Shs (TBLA) | 1.7 | $34M | 10M | 3.36 |
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| Longboard Pharmaceuticals In (LBPH) | 1.5 | $30M | 903k | 33.33 |
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| Xenon Pharmaceuticals (XENE) | 1.5 | $29M | 744k | 39.37 |
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| Cytokinetics Com New (CYTK) | 1.4 | $28M | 526k | 52.80 |
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| Kura Oncology (KURA) | 1.3 | $26M | 1.3M | 19.54 |
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| Arcus Biosciences Incorporated (RCUS) | 1.2 | $25M | 1.6M | 15.29 |
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| Denali Therapeutics (DNLI) | 1.2 | $24M | 834k | 29.13 |
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| Erasca (ERAS) | 1.2 | $24M | 8.9M | 2.73 |
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| Cullinan Oncology (CGEM) | 1.0 | $20M | 1.2M | 16.74 |
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| Tango Therapeutics (TNGX) | 1.0 | $20M | 2.6M | 7.70 |
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| Solid Biosciences Com New (SLDB) | 1.0 | $19M | 2.7M | 6.97 |
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| Prothena Corporation SHS (PRTA) | 0.9 | $18M | 1.1M | 16.73 |
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| NewAmsterdam Pharma Company NV Ordinary Shares (NAMS) | 0.8 | $15M | 921k | 16.60 |
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| Biohaven (BHVN) | 0.7 | $14M | 284k | 49.97 |
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| Korro Bio (KRRO) | 0.7 | $14M | 419k | 33.42 |
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| Applied Therapeutics (APLT) | 0.7 | $14M | 1.6M | 8.50 |
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| Gossamer Bio Call Option (GOSS) | 0.7 | $13M | 14M | 0.99 |
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| Instil Bio Com New (TIL) | 0.6 | $13M | 192k | 67.32 |
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| Edgewise Therapeutics (EWTX) | 0.5 | $11M | 404k | 26.69 |
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| Iovance Biotherapeutics (IOVA) | 0.5 | $10M | 1.1M | 9.39 |
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| Oric Pharmaceuticals (ORIC) | 0.5 | $10M | 1.0M | 10.25 |
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| Ionis Pharmaceuticals (IONS) | 0.5 | $10M | 250k | 40.06 |
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| Taysha Gene Therapies Com Shs (TSHA) | 0.5 | $9.8M | 4.9M | 2.01 |
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| Microsoft Corporation (MSFT) | 0.5 | $9.5M | 22k | 430.12 |
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| Cartesian Therapeutics Com New (RNAC) | 0.5 | $9.2M | 572k | 16.12 |
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| Acelyrin (SLRN) | 0.4 | $8.5M | 1.7M | 4.93 |
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| Phathom Pharmaceuticals (PHAT) | 0.4 | $8.3M | 461k | 18.08 |
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| Seer Com Cl A (SEER) | 0.4 | $7.9M | 4.0M | 1.97 |
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| Rapport Therapeutics (RAPP) | 0.4 | $7.9M | 384k | 20.48 |
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| Neurogene (NGNE) | 0.4 | $7.4M | 176k | 41.96 |
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| Generation Bio (GBIO) | 0.4 | $7.4M | 3.0M | 2.47 |
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| IHS Holding Ord Shs (IHS) | 0.4 | $7.0M | 2.4M | 2.99 |
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| CrowdStrike Holdings Cl A (CRWD) | 0.4 | $7.0M | 25k | 280.47 |
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| Vigil Neuroscience (VIGL) | 0.3 | $6.8M | 2.0M | 3.40 |
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| Foghorn Therapeutics (FHTX) | 0.3 | $6.7M | 721k | 9.31 |
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| Servicenow (NOW) | 0.3 | $6.7M | 7.5k | 894.39 |
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| Amazon (AMZN) | 0.3 | $6.5M | 35k | 186.33 |
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| Bioage Labs | 0.3 | $6.2M | 300k | 20.80 |
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| NVIDIA Corporation (NVDA) | 0.3 | $5.9M | 49k | 121.43 |
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| Syros Pharmaceuticals Com New (SYRS) | 0.3 | $5.6M | 2.6M | 2.15 |
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| Novocure Ord Shs (NVCR) | 0.3 | $5.5M | 351k | 15.63 |
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| Lexeo Therapeutics (LXEO) | 0.3 | $5.5M | 603k | 9.04 |
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| PDD Holdings Sponsored Ads (PDD) | 0.3 | $5.4M | 40k | 134.81 |
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| Allovir (ALVR) | 0.3 | $5.3M | 6.6M | 0.81 |
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| Black Diamond Therapeutics (BDTX) | 0.2 | $4.6M | 1.0M | 4.35 |
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| Alto Neuroscience Com Shs (ANRO) | 0.2 | $4.5M | 391k | 11.44 |
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| Dynatrace Com New (DT) | 0.2 | $4.4M | 83k | 53.47 |
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| Ionq Inc Pipe (IONQ) | 0.2 | $4.4M | 500k | 8.74 |
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| Taiwan Semiconductor Manufacturing Sponsored Ads (TSM) | 0.2 | $4.3M | 25k | 173.67 |
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| Agenus Com New (AGEN) | 0.2 | $4.2M | 775k | 5.48 |
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| Datadog Cl A Com (DDOG) | 0.2 | $3.8M | 33k | 115.06 |
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| ADC Therapeutics SA SHS (ADCT) | 0.2 | $3.7M | 1.2M | 3.15 |
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| Sea Sponsored Ads (SE) | 0.2 | $3.5M | 38k | 94.28 |
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| Ovid Therapeutics (OVID) | 0.2 | $3.4M | 2.9M | 1.18 |
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| Paypal Holdings Call Option (PYPL) | 0.2 | $3.2M | 41k | 78.03 |
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| Regenxbio Inc equity us cm (RGNX) | 0.1 | $3.0M | 284k | 10.49 |
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| New Oriental Education & Technology Group Spon Adr (EDU) | 0.1 | $2.9M | 39k | 75.84 |
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| Qualcomm (QCOM) | 0.1 | $2.6M | 15k | 170.05 |
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| HOOKIPA Pharma Com New (HOOK) | 0.1 | $2.4M | 567k | 4.30 |
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| Tourmaline Bio (TRML) | 0.1 | $2.4M | 91k | 25.71 |
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| Sagimet Biosciences Com Ser A (SGMT) | 0.1 | $2.0M | 725k | 2.77 |
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| Procore Technologies (PCOR) | 0.1 | $2.0M | 32k | 61.72 |
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| Ke Holdings Sponsored Ads (BEKE) | 0.1 | $2.0M | 100k | 19.91 |
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| Visa Com Cl A (V) | 0.1 | $1.9M | 7.0k | 274.95 |
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| Gritstone Oncology Ord (GRTS) | 0.1 | $1.9M | 3.3M | 0.58 |
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| Alphabet Cap Stk Cl A (GOOGL) | 0.1 | $1.8M | 11k | 165.83 |
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| Occidental Petroleum Corporation (OXY) | 0.1 | $1.8M | 35k | 51.54 |
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| Jfrog Ord Shs (FROG) | 0.1 | $1.8M | 61k | 29.04 |
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| Omega Therapeutics Common Stock (OMGA) | 0.1 | $1.6M | 1.3M | 1.22 |
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| Natera (NTRA) | 0.1 | $1.6M | 13k | 126.95 |
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| Palo Alto Networks (PANW) | 0.1 | $1.5M | 4.5k | 341.80 |
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| Elastic NV Ord Shs (ESTC) | 0.0 | $998k | 13k | 76.76 |
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| Intel Corporation (INTC) | 0.0 | $938k | 40k | 23.46 |
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| Meta Platforms Cl A (META) | 0.0 | $859k | 1.5k | 572.44 |
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| Kronos Bio (KRON) | 0.0 | $843k | 843k | 1.00 |
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| Terns Pharmaceuticals (TERN) | 0.0 | $834k | 100k | 8.34 |
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| Rubrik Cl A (RBRK) | 0.0 | $804k | 25k | 32.15 |
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| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $771k | 755k | 1.02 |
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| Dollar Tree (DLTR) | 0.0 | $703k | 10k | 70.32 |
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| Nu Holdings Ord Shs Cl A (NU) | 0.0 | $683k | 50k | 13.65 |
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| Adobe Systems Incorporated (ADBE) | 0.0 | $518k | 1.0k | 517.78 |
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| Ironwood Pharmaceuticals Com Cl A (IRWD) | 0.0 | $455k | 111k | 4.12 |
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| Kanzhun Sponsored Ads (BZ) | 0.0 | $434k | 25k | 17.36 |
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| Remitly Global (RELY) | 0.0 | $335k | 25k | 13.39 |
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| Glycomimetics (GLYC) | 0.0 | $332k | 2.0M | 0.17 |
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| Cyclerion Therapeutics (CYCN) | 0.0 | $301k | 116k | 2.59 |
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| Caribou Biosciences (CRBU) | 0.0 | $207k | 105k | 1.96 |
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| Perception Capital Corp III *w Exp 99/99/999 Call Option (PFTAW) | 0.0 | $3.8k | 127k | 0.03 |
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Past Filings by Siren
SEC 13F filings are viewable for Siren going back to 2024
- Siren 2024 Q3 filed Nov. 13, 2024