Vanguard
|
March 31, 2019
|
23.11M
|
$563.35M
|
Fmr
|
June 30, 2019
|
19.21M
|
$889.85M
|
BlackRock
|
June 30, 2019
|
17.79M
|
$824.43M
|
Redmile
|
March 31, 2019
|
10.97M
|
$267.46M
|
Franklin Resources
|
March 31, 2019
|
10.50M
|
$256.05M
|
State Street Corporation
|
March 31, 2019
|
7.28M
|
$177.48M
|
T. Rowe Price Associates
|
June 30, 2019
|
5.42M
|
$251.00M
|
Goldman Sachs
|
June 30, 2019
|
4.03M
|
$186.51M
|
Baker Bros. Advisors
|
March 31, 2019
|
3.84M
|
$93.68M
|
HBK Investments
|
June 30, 2019
|
3.49M
|
$161.53M
|
Bvf
|
March 31, 2019
|
3.42M
|
$83.39M
|
Morgan Stanley
|
March 31, 2019
|
3.37M
|
$82.21M
|
Paulson & Co
|
June 30, 2019
|
3.28M
|
$151.76M
|
Millennium Management
|
June 30, 2019
|
3.02M
|
$140.01M
|
Alpine Associates Management
|
June 30, 2019
|
3.01M
|
$139.53M
|
Fil
|
June 30, 2019
|
2.87M
|
$132.74M
|
Pentwater Capital Management
|
June 30, 2019
|
2.77M
|
$128.10M
|
Geode Capital Management
|
March 31, 2019
|
2.76M
|
$67.31M
|
TIG Advisors
|
June 30, 2019
|
2.74M
|
$126.82M
|
Northern Trust
|
June 30, 2019
|
2.69M
|
$124.54M
|
Marshall Wace North America
|
March 31, 2019
|
2.55M
|
$62.28M
|
Inves
|
March 31, 2019
|
2.48M
|
$60.44M
|
CNH Partners
|
June 30, 2019
|
2.41M
|
$111.52M
|
Susquehanna International
|
June 30, 2019
|
2.34M
|
$108.60M
|
Macquarie
|
June 30, 2019
|
2.24M
|
$103.81M
|
Artal Group S.A.
|
March 31, 2019
|
2.00M
|
$48.76M
|
Dr. Jeffrey R. Jay, M.D.
|
March 31, 2019
|
2.00M
|
$48.76M
|
venBio Select Advisor
|
March 31, 2019
|
2.00M
|
$48.76M
|
Nuveen Asset Management
|
June 30, 2019
|
1.99M
|
$92.34M
|
Citi
|
June 30, 2019
|
1.69M
|
$78.40M
|
Name Goodman & Company, Investment Counsel
|
March 31, 2019
|
1.60M
|
$37.35M
|
Wellington Management Company
|
June 30, 2019
|
1.57M
|
$72.71M
|
Jpmorgan Chase & Co
|
June 30, 2019
|
1.46M
|
$67.61M
|
Brown Advisory Holdings Incorporated
|
June 30, 2019
|
1.41M
|
$65.10M
|
Ubs Global Asset Management Americas
|
June 30, 2019
|
1.39M
|
$64.24M
|
Charles Schwab Investment Management
|
June 30, 2019
|
1.38M
|
$63.90M
|
Renaissance Technologies
|
June 30, 2019
|
1.34M
|
$62.30M
|
Ing Investment Management
|
March 31, 2019
|
1.33M
|
$32.31M
|
Melqart Asset Management
|
June 30, 2019
|
1.28M
|
$59.43M
|
First Light Asset Management
|
June 30, 2019
|
1.21M
|
$56.18M
|
Credit Suisse AG
|
March 31, 2019
|
1.20M
|
$29.71M
|
Two Sigma Investments
|
March 31, 2019
|
1.19M
|
$28.93M
|
Perceptive Advisors
|
June 30, 2019
|
1.04M
|
$48.11M
|
Candriam Luxembourg S.C.A.
|
June 30, 2019
|
992510
|
$45.78M
|
Bank of New York Mellon
|
June 30, 2019
|
975210
|
$45.18M
|
Two Sigma Advisers
|
March 31, 2019
|
965413
|
$23.54M
|
Carlson Capital
|
June 30, 2019
|
947234
|
$43.89M
|
Gabelli Funds
|
June 30, 2019
|
913212
|
$42.31M
|
Sectoral Asset Management
|
March 31, 2019
|
909968
|
$22.19M
|
Lord, Abbett & Co
|
March 31, 2019
|
901813
|
$21.99M
|
Assenagon Asset Management S.A.
|
June 30, 2019
|
888960
|
$41.19M
|
Bank of America Corporation
|
March 31, 2019
|
850637
|
$20.74M
|
Gail Mannix
|
June 30, 2019
|
837563
|
$38.80M
|
Deutsche Bank Aktiengesellschaft
|
March 31, 2019
|
820305
|
$19.89M
|
Water Island Capital
|
June 30, 2019
|
819000
|
$37.94M
|
Handelsbanken Fonder AB
|
June 30, 2019
|
795712
|
$36.87M
|
Ameriprise Financial
|
March 31, 2019
|
785480
|
$19.15M
|
Schonfeld Strategic Advisors
|
March 31, 2019
|
686100
|
$16.73M
|
Man
|
June 30, 2019
|
680000
|
$31.50M
|
Arp Americas
|
June 30, 2019
|
638819
|
$29.60M
|
Canada Pension Plan Investment Board
|
June 30, 2019
|
596114
|
$27.62M
|
Allianz Asset Management AG
|
June 30, 2019
|
592903
|
$27.47M
|
Zweig-DiMenna Associates
|
June 30, 2019
|
590640
|
$27.36M
|
Federated Investors
|
March 31, 2019
|
563031
|
$13.56M
|
Columbus Circle Investors
|
June 30, 2019
|
553980
|
$25.67M
|
Peregrine Capital Management
|
June 30, 2019
|
544364
|
$25.22M
|
Gabelli Securities
|
June 30, 2019
|
543580
|
$25.18M
|
D. E. Shaw & Co
|
June 30, 2019
|
542638
|
$25.14M
|
Cormorant Asset Management
|
March 31, 2019
|
500000
|
$12.19M
|
Fosun International
|
June 30, 2019
|
498733
|
$23.05M
|
Alliancebernstein
|
March 31, 2019
|
433749
|
$10.57M
|
Driehaus Capital Management
|
June 30, 2019
|
432003
|
$20.01M
|
Pictet Asset Management
|
June 30, 2019
|
428974
|
$19.87M
|
Syquant Capital Sas
|
June 30, 2019
|
417100
|
$19.32M
|
Dimensional Fund Advisors
|
June 30, 2019
|
407674
|
$18.89M
|
Swiss National Bank
|
June 30, 2019
|
406100
|
$18.81M
|
Principal Financial
|
June 30, 2019
|
398728
|
$18.47M
|
SG Americas Securities
|
June 30, 2019
|
381771
|
$17.69M
|
Twin Tree Management
|
June 30, 2019
|
370800
|
$17.18M
|
Hambrecht & Quist Capital Management
|
March 31, 2019
|
364166
|
$8.88M
|
Frontier Capital Management
|
March 31, 2019
|
342571
|
$8.35M
|
California State Teachers Retirement System
|
March 31, 2019
|
323419
|
$7.88M
|
Neuberger Berman
|
June 30, 2019
|
306225
|
$14.19M
|
Caption Management
|
June 30, 2019
|
300000
|
$13.90M
|
Glazer Capital
|
June 30, 2019
|
296000
|
$13.71M
|
DekaBank Deutsche Girozentrale
|
June 30, 2019
|
292400
|
$13.51M
|
Rhumbline Advisers
|
March 31, 2019
|
288951
|
$7.04M
|
American Century Companies
|
June 30, 2019
|
276170
|
$12.79M
|
Taconic Capital Advisors
|
June 30, 2019
|
275000
|
$12.74M
|
State of Wisconsin Investment Board
|
March 31, 2019
|
274500
|
$6.69M
|
Russell Investments
|
June 30, 2019
|
268659
|
$12.45M
|
CalPERS
|
June 30, 2019
|
266400
|
$12.34M
|
Blue Mountain Capital Management
|
March 31, 2019
|
265267
|
$6.47M
|
Jefferies
|
June 30, 2019
|
260196
|
$12.05M
|
AQR Capital Management
|
June 30, 2019
|
258533
|
$11.98M
|
Wells Fargo & Company
|
June 30, 2019
|
251110
|
$11.64M
|
New York State Common Retirement Fund
|
June 30, 2019
|
241096
|
$11.17M
|